Guest guest Posted November 9, 2007 Report Share Posted November 9, 2007 Hi, I attended a meeting of the Sarc Education and Research Foundation 2 weeks ago. The speaker was a Sarc researcher from Drexel Medical University and Hahneman Critical Care Hospital in Philadelphia. He is looking at a possible new trigger substance for Sarcoidosis, inorganic materials like Silicon, Talc, Metals (including aluminum, titanium, magnesium, etc.), and other similar substances. These materials can be located within the central macrocell of the granuloma by performing a test of the biopsy using polarized light under a microscope. If there is a material that will fluoresce under the polarized light, it is an inorganic material. It is beginning to be understood that you can determine what is causing the macrophages to respond by locating materials within the macrocell of the granuloma. This works if you are looking for things that are not normal body chemicals of substances. It falls apart if the trigger is something like an environmental item like temperature or humidity. It also makes it impossible to detect normal organic compounds that may be the trigger. But, it does help minimize the number of substances that could be considered ideopathic. While this may not be an earth shattering finding, if it is correct, many patients with ideopathic symptoms may have one more tool to understand the trigger to their EN or Sarc. While the Dr. is researching only the trigger substances, he readily admitted that Sarcoidosis is a complex response and requires several things to occur. These include: 1) A genetic tendency to the disease or disorder that allows it to express itself within certain persons and not others. 2) A trigger substance. For Sarcoidosis, this trigger must not be capable of being determined as infection, known immune disorder, neurologic, or pathologic. 3) A dose rate of the trigger substance. Since no researcher currently can define any of the above conditions, we have no good diagnostic tools to better allow the medical field to determine the best treatment for any patient. Because of this, every treatment is an experiment and the patient is the WHITE RAT! While the research is no where close to complete, it is progressing. Some times, it is just good to know that there is progress being made. Wayne Quote Link to comment Share on other sites More sharing options...
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