Guest guest Posted February 15, 2007 Report Share Posted February 15, 2007 Dear Group,This link had good general info about EN which could be incorporated into an EN phamplet.http://www.aafp.org/afp/20000815/804.html Nodular Eruptions FIGURE 8. Erythema nodosum. Erythema NodosumErythema nodosum is an acute inflammatory and immunologic process involving the panniculus adiposus (the fatty tissue layer underlying the skin).1 A number of etiologies have been identified (Table 4).1,4 This condition is more common in women than in men. Presenting features often include fever, malaise and arthralgias. The characteristic nodules are painful and tender. The lesions most often develop on the lower legs, knees and arms (Figure 9). The course of erythema nodosum depends on the specific cause, but spontaneous resolution can be expected within six weeks.1,2 Other CausesIn immunocompromised patients, disseminated fungal infections may produce nodular lesions. Disseminated candidiasis may present with diffuse nonerythematous nodules in an immunocompromised patient who has fever and myalgias. Other fungal infections to consider include cryptococcosis, blastomycosis, histoplasmosis, coccidioidomycosis and sporotrichosis.2 Rarely, bacteria such as Nocardia, Pseudomonas and Mycobacterium species may produce nodular lesions.1,4 TABLE 4Etiologies of Erythema Nodosum Idiopathic (40 percent of cases)Infectious causes Beta-hemolytic streptococci Yersinia species Hepatitis C virus Mycobacterium species Chlamydia trachomatis Coccidioides immitisNoninfectious causes Medications Sulfonamides Oral contraceptivesSystemic lupus erythematosusSarcoidosisInflammatory Bowel Disease [ulcerative Colitis and Crohn's Disease]Behçet's syndromePregnancy Information from Fitzpatrick TB, et al. Color atlas and synopsis of clinical dermatology: common and serious diseases. 3d ed. New York: McGraw-Hill, Health Professions Division, 1997, and Weber DI, Cohen MS, Fine JD. The acutely ill patient with fever and rash. In: Mandell GL, JE, Dolin R, eds. Mandell, , and 's Principles and practice of infectious diseases. 5th ed. Philadelphia: Churchill Livingstone, 1999:633-50. Quote Link to comment Share on other sites More sharing options...
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