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Additional info for a phamplet/Grahic Artist Needed to help make our Phamplet

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Dear Group,This link had good general info about EN which could be incorporated into an EN phamplet.http://www.aafp.org/afp/20000815/804.html Nodular Eruptions FIGURE 8.

Erythema nodosum. Erythema NodosumErythema nodosum is an acute inflammatory

and immunologic process involving the panniculus adiposus (the fatty tissue

layer underlying the skin).1 A number of

etiologies have been identified (Table 4).1,4 This condition is more common in women than in

men. Presenting features often include fever, malaise and arthralgias. The

characteristic nodules are painful and tender. The lesions most often develop

on the lower legs, knees and arms (Figure 9). The course of erythema

nodosum depends on the specific cause, but spontaneous resolution can be

expected within six weeks.1,2 Other CausesIn immunocompromised patients, disseminated

fungal infections may produce nodular lesions. Disseminated candidiasis may

present with diffuse nonerythematous nodules in an immunocompromised patient

who has fever and myalgias. Other fungal infections to consider include

cryptococcosis, blastomycosis, histoplasmosis, coccidioidomycosis and

sporotrichosis.2 Rarely, bacteria such as Nocardia, Pseudomonas and Mycobacterium

species may produce nodular lesions.1,4 TABLE 4Etiologies

of Erythema Nodosum Idiopathic

(40 percent of cases)Infectious causes Beta-hemolytic

streptococci Yersinia

species Hepatitis C

virus Mycobacterium

species Chlamydia

trachomatis Coccidioides

immitisNoninfectious

causes Medications Sulfonamides Oral

contraceptivesSystemic lupus erythematosusSarcoidosisInflammatory Bowel Disease [ulcerative Colitis and Crohn's Disease]Behçet's syndromePregnancy Information from Fitzpatrick

TB, et al. Color atlas and synopsis of clinical dermatology: common and serious

diseases. 3d ed. New York: McGraw-Hill, Health Professions Division, 1997, and

Weber DI, Cohen MS, Fine JD. The acutely ill patient with fever and rash. In:

Mandell GL, JE, Dolin R, eds. Mandell, , and 's

Principles and practice of infectious diseases. 5th ed. Philadelphia: Churchill

Livingstone, 1999:633-50.

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