Guest guest Posted February 4, 2006 Report Share Posted February 4, 2006 The problem is that you don't have one, single virus in your body, but a "cloud," which is composed of viruses with different mutations.Once you have a resistance mutation, you have it. Likewise, even if "wild type" virus emerges as a dominant strain, the resistant strains are still there, and if drug treatment favors them, they will quickly emerge as dominant species.On Feb 4, 2006, at 11:28 AM, PozHealth wrote:Within months after infection, the virus mutates into that virus which is best adapted to life within your body, regardless of the original viral type. Barrowpozbod@... Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 4, 2006 Report Share Posted February 4, 2006 This does seem to be the current thinking, and it does seem to stand on some very solid theoretical assumptions. However, I don't belive all the underlying premises have actually been demonstrated to be fact. Of course, there have been other well-founded beliefs about the viral behavior of HIV that made sense in their time but as our understanding of the virus changes, it forced us to reevaluate our theoretical assumptions. I think that this whole area of study, individuals seroconverting with resistant strains of the virus, is really new and up for grabs. Wild type The problem is that you don't have one, single virus in your body, but a "cloud," which is composed of viruses with different mutations. Once you have a resistance mutation, you have it. Likewise, even if "wild type" virus emerges as a dominant strain, the resistant strains are still there, and if drug treatment favors them, they will quickly emerge as dominant species. On Feb 4, 2006, at 11:28 AM, PozHealth wrote: Within months after infection, the virus mutates into that virus which is best adapted to life within your body, regardless of the original viral type. Barrow pozbod@... Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 4, 2006 Report Share Posted February 4, 2006 This does seem to be the current thinking, and it does seem to stand on some very solid theoretical assumptions. However, I don't belive all the underlying premises have actually been demonstrated to be fact. Of course, there have been other well-founded beliefs about the viral behavior of HIV that made sense in their time but as our understanding of the virus changes, it forced us to reevaluate our theoretical assumptions. I think that this whole area of study, individuals seroconverting with resistant strains of the virus, is really new and up for grabs. Wild type The problem is that you don't have one, single virus in your body, but a "cloud," which is composed of viruses with different mutations. Once you have a resistance mutation, you have it. Likewise, even if "wild type" virus emerges as a dominant strain, the resistant strains are still there, and if drug treatment favors them, they will quickly emerge as dominant species. On Feb 4, 2006, at 11:28 AM, PozHealth wrote: Within months after infection, the virus mutates into that virus which is best adapted to life within your body, regardless of the original viral type. Barrow pozbod@... Quote Link to comment Share on other sites More sharing options...
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