RE: Cerebal Folate receptor antibodies in autism spectrum disorder

[Guest guest]

Thanks for forward !They say:Compared with controls, significantly higher improvement ratings were observed in treated

children over a mean period of 4 months in verbal communication, receptive and expressive

language, attention and stereotypical behavior. Approximately one-third of treated children

demonstrated moderate to much improvement. The incidence of adverse effects was low.I've been following reports from many parents whose kids are on (or have tried) leucovorin – judging by those reports yes true that many see big improvements with it, but there are also quite a few negative reports, where kids don't tolerate it at all, no even after tweaking doses, protocols, adjustment periods. Most of those negatives return to baseline after stopping.But when it works it mostly brings BIG improvements. Reply-To: "Autism-Biomedical-Europe " <Autism-Biomedical-Europe >Date: Tue, 10 Jan 2012 15:30:33 +0000To: "Autism-Biomedical-Europe " <Autism-Biomedical-Europe >Subject: Cerebal Folate receptor antibodies in autism spectrum disorder

http://www.nature.com/mp/journal/vaop/ncurrent/pdf/mp2011175a.pdf

x

[Guest guest]

Thanks for forward !They say:Compared with controls, significantly higher improvement ratings were observed in treated

children over a mean period of 4 months in verbal communication, receptive and expressive

language, attention and stereotypical behavior. Approximately one-third of treated children

demonstrated moderate to much improvement. The incidence of adverse effects was low.I've been following reports from many parents whose kids are on (or have tried) leucovorin – judging by those reports yes true that many see big improvements with it, but there are also quite a few negative reports, where kids don't tolerate it at all, no even after tweaking doses, protocols, adjustment periods. Most of those negatives return to baseline after stopping.But when it works it mostly brings BIG improvements. Reply-To: "Autism-Biomedical-Europe " <Autism-Biomedical-Europe >Date: Tue, 10 Jan 2012 15:30:33 +0000To: "Autism-Biomedical-Europe " <Autism-Biomedical-Europe >Subject: Cerebal Folate receptor antibodies in autism spectrum disorder

http://www.nature.com/mp/journal/vaop/ncurrent/pdf/mp2011175a.pdf

x

[Guest guest]

Thanks for forward !They say:Compared with controls, significantly higher improvement ratings were observed in treated

children over a mean period of 4 months in verbal communication, receptive and expressive

language, attention and stereotypical behavior. Approximately one-third of treated children

demonstrated moderate to much improvement. The incidence of adverse effects was low.I've been following reports from many parents whose kids are on (or have tried) leucovorin – judging by those reports yes true that many see big improvements with it, but there are also quite a few negative reports, where kids don't tolerate it at all, no even after tweaking doses, protocols, adjustment periods. Most of those negatives return to baseline after stopping.But when it works it mostly brings BIG improvements. Reply-To: "Autism-Biomedical-Europe " <Autism-Biomedical-Europe >Date: Tue, 10 Jan 2012 15:30:33 +0000To: "Autism-Biomedical-Europe " <Autism-Biomedical-Europe >Subject: Cerebal Folate receptor antibodies in autism spectrum disorder

http://www.nature.com/mp/journal/vaop/ncurrent/pdf/mp2011175a.pdf

x

[Guest guest]

Thanks for this, . I know on the B6 children list (which is mainly for

families with a child with an inborn error of metabolism known as pyridoxine

dependency) some are also using Leucorovin. I don't understand quite what's

going on - may raise it with Heny's neuro when we get the results from the

analysis of his CSF neurotransmitters.

Margaret

>

>

> http://www.nature.com/mp/journal/vaop/ncurrent/pdf/mp2011175a.pdf

>

> x

>

[Guest guest]

Thanks for this, . I know on the B6 children list (which is mainly for

families with a child with an inborn error of metabolism known as pyridoxine

dependency) some are also using Leucorovin. I don't understand quite what's

going on - may raise it with Heny's neuro when we get the results from the

analysis of his CSF neurotransmitters.

Margaret

>

>

> http://www.nature.com/mp/journal/vaop/ncurrent/pdf/mp2011175a.pdf

>

> x

>

[Guest guest]

Thanks for this, . I know on the B6 children list (which is mainly for

families with a child with an inborn error of metabolism known as pyridoxine

dependency) some are also using Leucorovin. I don't understand quite what's

going on - may raise it with Heny's neuro when we get the results from the

analysis of his CSF neurotransmitters.

Margaret

>

>

> http://www.nature.com/mp/journal/vaop/ncurrent/pdf/mp2011175a.pdf

>

> x

>

[Guest guest]

Isn't it a problem to get hold of a large enough dose unless you have a

prescription?

MArgaret

>

> Thanks for forward !

>

> They say:

>

> Compared with controls, significantly higher improvement ratings were

> observed in treated

>

> children over a mean period of 4 months in verbal communication, receptive

> and expressive

>

> language, attention and stereotypical behavior. Approximately one-third of

> treated children

>

> demonstrated moderate to much improvement. The incidence of adverse effects

> was low.

>

>

>

> I've been following reports from many parents whose kids are on (or have

> tried) leucovorin ­ judging by those reports yes true that many see big

> improvements with it, but there are also quite a few negative reports, where

> kids don't tolerate it at all, no even after tweaking doses, protocols,

> adjustment periods. Most of those negatives return to baseline after

> stopping.

>

>

>

> But when it works it mostly brings BIG improvements.

>

>

>

>

>

>

>

>

>

>

>

>

> Reply-To: " Autism-Biomedical-Europe "

> <Autism-Biomedical-Europe >

> Date: Tue, 10 Jan 2012 15:30:33 +0000

> To: " Autism-Biomedical-Europe "

> <Autism-Biomedical-Europe >

> Subject: Cerebal Folate receptor antibodies in

> autism spectrum disorder

>

>

>

>

>

>

> http://www.nature.com/mp/journal/vaop/ncurrent/pdf/mp2011175a.pdf

>

> x

>

[Guest guest]

Isn't it a problem to get hold of a large enough dose unless you have a

prescription?

MArgaret

>

> Thanks for forward !

>

> They say:

>

> Compared with controls, significantly higher improvement ratings were

> observed in treated

>

> children over a mean period of 4 months in verbal communication, receptive

> and expressive

>

> language, attention and stereotypical behavior. Approximately one-third of

> treated children

>

> demonstrated moderate to much improvement. The incidence of adverse effects

> was low.

>

>

>

> I've been following reports from many parents whose kids are on (or have

> tried) leucovorin ­ judging by those reports yes true that many see big

> improvements with it, but there are also quite a few negative reports, where

> kids don't tolerate it at all, no even after tweaking doses, protocols,

> adjustment periods. Most of those negatives return to baseline after

> stopping.

>

>

>

> But when it works it mostly brings BIG improvements.

>

>

>

>

>

>

>

>

>

>

>

>

> Reply-To: " Autism-Biomedical-Europe "

> <Autism-Biomedical-Europe >

> Date: Tue, 10 Jan 2012 15:30:33 +0000

> To: " Autism-Biomedical-Europe "

> <Autism-Biomedical-Europe >

> Subject: Cerebal Folate receptor antibodies in

> autism spectrum disorder

>

>

>

>

>

>

> http://www.nature.com/mp/journal/vaop/ncurrent/pdf/mp2011175a.pdf

>

> x

>

[Guest guest]

Isn't it a problem to get hold of a large enough dose unless you have a

prescription?

MArgaret

>

> Thanks for forward !

>

> They say:

>

> Compared with controls, significantly higher improvement ratings were

> observed in treated

>

> children over a mean period of 4 months in verbal communication, receptive

> and expressive

>

> language, attention and stereotypical behavior. Approximately one-third of

> treated children

>

> demonstrated moderate to much improvement. The incidence of adverse effects

> was low.

>

>

>

> I've been following reports from many parents whose kids are on (or have

> tried) leucovorin ­ judging by those reports yes true that many see big

> improvements with it, but there are also quite a few negative reports, where

> kids don't tolerate it at all, no even after tweaking doses, protocols,

> adjustment periods. Most of those negatives return to baseline after

> stopping.

>

>

>

> But when it works it mostly brings BIG improvements.

>

>

>

>

>

>

>

>

>

>

>

>

> Reply-To: " Autism-Biomedical-Europe "

> <Autism-Biomedical-Europe >

> Date: Tue, 10 Jan 2012 15:30:33 +0000

> To: " Autism-Biomedical-Europe "

> <Autism-Biomedical-Europe >

> Subject: Cerebal Folate receptor antibodies in

> autism spectrum disorder

>

>

>

>

>

>

> http://www.nature.com/mp/journal/vaop/ncurrent/pdf/mp2011175a.pdf

>

> x

>

[Guest guest]

Hi Natasa

When we were at NAA conference in November Dr Rosingol did his presentation about this, i had a whole light bulb moment, as one of Harry's test (not sure which one) said that he required folinic acid and i have been giving it too him since July, it's hard to tell what is working as i am doing so much but his speech is coming, all be it slowly but it seems with Harry i am just having steedy progress no big Wow but im as long as he keeps making progress in any shape or form then happy.

x

To: Autism-Biomedical-Europe From: neno@...Date: Tue, 10 Jan 2012 16:11:12 +0000Subject: Re: Cerebal Folate receptor antibodies in autism spectrum disorder

Thanks for forward !

They say:

Compared with controls, significantly higher improvement ratings were observed in treated

children over a mean period of 4 months in verbal communication, receptive and expressive

language, attention and stereotypical behavior. Approximately one-third of treated children

demonstrated moderate to much improvement. The incidence of adverse effects was low.

I've been following reports from many parents whose kids are on (or have tried) leucovorin – judging by those reports yes true that many see big improvements with it, but there are also quite a few negative reports, where kids don't tolerate it at all, no even after tweaking doses, protocols, adjustment periods. Most of those negatives return to baseline after stopping.

But when it works it mostly brings BIG improvements.

Reply-To: "Autism-Biomedical-Europe " <Autism-Biomedical-Europe >Date: Tue, 10 Jan 2012 15:30:33 +0000To: "Autism-Biomedical-Europe " <Autism-Biomedical-Europe >Subject: Cerebal Folate receptor antibodies in autism spectrum disorder

http://www.nature.com/mp/journal/vaop/ncurrent/pdf/mp2011175a.pdf x