Re: RE: selenomethionine

[Guest guest]

Hi ,

I've been taking selenium for many years, along with vitamin E. I read somewhere that selenium slows down the progression of HIV disease, and works well with vitamin E. I certainly think it has helped my KS stay in remission. I had the coxsackie virus A and B when I was in hospital in March. I had periocarditus and costocondritus, inflamation in the periocardiem and floating ribs caused by these virus. I certainly think selenium helped. I had a friend that was in hospital in 2004 with periocarditus, and she had to have her pericardiem area pumped because of fluid build up. Mine was bad enough, but the docs used IV anti-inflamatories and IV dieretics (sp?) to clear my inflamatory fluids up. So, I firmly think selenium help alot.

Mooney wrote:

Selenium, in any usable form, also has merit for its potential to reduce cancer, its effect on improving glutathione peroxidase production activity, and its effect on reducing activities of a number of viruses, including HIV and sackie virus B5 replication. Dr. Will of the University of Alabama has a lot to say about selenium's role in reducing replication of HIV. He told me he thought HIV+ people should safely supplement with 600 mcg per day.

Note that selenomethione is frequently claimed to be significantly better than its less expensive competitor selenite, but the studies generally confirm little difference, with selenite having more long-term studies and some indication that it is, in fact, superior, with less potential for toxicity at higher doses. See: http://www.supernutritionusa.com/selenium.pdf

Mooney

www.michaelmooney.net

www.medibolic.com

www.powerusa.org

From: Al Benson Sent: Thursday, September 29, 2005 7:10 AMTo: powertx@...; ' Mooney'; Subject: selenomethionine

Selenomethionine aka SeMet

Any thoughts on taking this stuff? Read to the bottom

Effects of 5 HIV Protease Inhibitors on Vasomotor Function and Superoxide Anion Production in Porcine Coronary Arteries.Chai H, Yang H, Yan

S, Li M, Lin PH, Lumsden AB, Yao Q, Chen C.From the Molecular Surgeon Research Center, Division of Vascular Surgery and Endovascular Therapy, E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX.HIV protease inhibitors (PIs) have been implicated to cause cardiovascular complications. Previous studies demonstrated that the PI ritonavir (RTV) caused endothelial dysfunction in porcine arteries. This study investigated and compared the effects of 5 commonly used PIs on vasomotor function, endothelial nitric oxide synthase (eNOS) expression, and oxidative stress in porcine coronary arteries. Vessel rings were incubated with 15 muM of RTV, amprenavir (APV), saquinavir (SQV), indinavir (IDV), or nelfinavir (NFV) for 24 hours. Vasomotor

function was studied using a myograph system. The contractility of the rings was significantly reduced for RTV and SQV. In response to bradykinin at 10 M, the endothelium-dependent relaxation was significantly reduced for RTV, APV, and SQV. The eNOS mRNA levels were significantly reduced for RTV, APV, and SQV. Furthermore, the superoxide anion (O2) levels of the vessels were significantly increased for RTV and APV. It was found that nitric oxide production was decreased, whereas the level of nitrotyrosine proteins was increased in RTV-treated vessels. Furthermore, antioxidant seleno-L-methionine (SeMet) reversed RTV-induced O2 production and vasomotor dysfunction. Thus, the HIV PIs RTV, APV, and SQV at 15 muM have more potent in vitro effects on vasomotor dysfunction, eNOS downregulation, and O2 production than IDV and NFV. The antioxidant SeMet can block these adverse effects of RTV. The results

suggest that antioxidant therapy may have applications for controlling PI-associated cardiovascular complications.

SEIZE THE DAY! ENJOY TODAY, SMELL THE ROSES AND HUG YOURSELF

Yahoo! for Good Click here to donate to the Hurricane Katrina relief effort.