Why do CD4 cell counts fail to rise in some patients with undetectable viral loa

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Why do CD4 cell counts fail to rise in some patients with undetectable viralloads?http://www.aidsmap.com/en/news/B1BCF83C-6FA3-4876-9E81-C7C0FC381AD6.asp?wk=1

Low-level regeneration of CD4 cell counts in patients with prolongedundetectable viral loads may occur due to a combination of increased celldeath and reduced production of new cells in the thymus, according to aprospective case-control study published in the on-line edition of TheJournal of Infectious Diseases. Despite this, the study suggested thatresponses to some disease-causing organisms are not impaired in thesepatients.

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