Re: How soon do SSRI negatives begin?

[Guest guest]

For us, it was after increased to 1/4 of 10mg.

Jin

> When a child demonstrates negative behaviors from an SSRI, when do

they typically begin? I know the positives can take weeks to appear,

but do the negatives show up within a day or so?

> Garrett (2 years, 8 months) started Paxil (1/8 of a 10mg tablet

every day) a week ago. Tomorrow, we go up to 1/4 of a pill.

> We've seen none of the negatives (hyperness, sleep problems, etc.)

I've so commonly read about on this list. We also think we may be

starting to see some improvements in eye contact and overall

happiness.

> Is it safe to assume he's out of the woods as to negatives on

Paxil, at least with respect to the dose he's presently on?

> Thanks for the input --

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[Guest guest]

Hi I found paxil had an immediate effect - it wasn't too bad but not for us -

but my guy became just soooo happy he just wanted to walk and hype around all

day - he also stopped eating this went on for 5 days he lost about 5 pounds - we

stopped right there - this was on 5mg and then within a day or two down to

2.5mg. We are now on Zoloft and its been amazing lovely slow improvements over

time - happy but normal and eating. Like most things trial and error you just

have to try these things.

Regards

Terri NZ

Re: How soon do SSRI negatives begin?

For us, it was after increased to 1/4 of 10mg.

Jin

> When a child demonstrates negative behaviors from an SSRI, when do

they typically begin? I know the positives can take weeks to appear,

but do the negatives show up within a day or so?

> Garrett (2 years, 8 months) started Paxil (1/8 of a 10mg tablet

every day) a week ago. Tomorrow, we go up to 1/4 of a pill.

> We've seen none of the negatives (hyperness, sleep problems, etc.)

I've so commonly read about on this list. We also think we may be

starting to see some improvements in eye contact and overall

happiness.

> Is it safe to assume he's out of the woods as to negatives on

Paxil, at least with respect to the dose he's presently on?

> Thanks for the input --

______________________________

``````````````````````````````

Responsibility for the content of this message lies strictly with

the original author, and is not necessarily endorsed by or the

opinion of the Research Institute.

```````````````````````````````````````

[Guest guest]

My son is also on Zoloft and he is getting 12. 5 mg does that seem a like a

high dose?

La Toya

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[Guest guest]

The only negatives we had were spaciness and diarrhea (tho I don't know

for sure if the Paxil was causing the diarrhea). Spaciness started

immediately, was gone by the end of week 1 and the diarrhea started with the

higher dose and also lasted a week. I think I've heard others say it takes

about a month for everything to settle down with SSRIs. Becky

How soon do SSRI negatives begin?

> When a child demonstrates negative behaviors from an SSRI, when do they

typically begin? I know the positives can take weeks to appear, but do the

negatives show up within a day or so?

>

> Garrett (2 years, 8 months) started Paxil (1/8 of a 10mg tablet every day)

a week ago. Tomorrow, we go up to 1/4 of a pill.

>

> We've seen none of the negatives (hyperness, sleep problems, etc.) I've so

commonly read about on this list. We also think we may be starting to see

some improvements in eye contact and overall happiness.

>

> Is it safe to assume he's out of the woods as to negatives on Paxil, at

least with respect to the dose he's presently on?

>

> Thanks for the input --

>

>

>

>

>

> Responsibility for the content of this message lies strictly with

> the original author, and is not necessarily endorsed by or the

> opinion of the Research Institute.

>

>

>

[Guest guest]

Does anyone know physiologically what is going on with

our kids when they have these symptoms with the

ssri's? And why do these symptoms then sometimes pass

and lead to a brighter child? Why does it seem to

have to get worse before it gets better? Barb

--- & Becky <beckeric@...> wrote:

> The only negatives we had were spaciness and

> diarrhea (tho I don't know

> for sure if the Paxil was causing the diarrhea).

> Spaciness started

> immediately, was gone by the end of week 1 and the

> diarrhea started with the

> higher dose and also lasted a week. I think I've

> heard others say it takes

> about a month for everything to settle down with

> SSRIs. Becky

How soon do SSRI negatives begin?

> > When a child demonstrates negative behaviors from

> an SSRI, when do they

> typically begin? >>>>

//thread truncated//

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[Guest guest]

Dear ,

Sounds like a great start on the SSRI!! We noticed hyperness right away

with , but after lowering the dose he settled out. Hope all continues to go

well with Garrett.

By the way , how is Garrett doing on the IMGG ? Have you noticed any effects yet

or is it still to soon to tell ? Take care,

How soon do SSRI negatives begin?

When a child demonstrates negative behaviors from an SSRI, when do they

typically begin? I know the positives can take weeks to appear, but do the

negatives show up within a day or so?

=== message truncated ===

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[Guest guest]

Not that I'll know the answer, but how old is he and how much does he weigh?

Caroline

> On 8/22/03 3:38 PM, " THELION90@... " <THELION90@...> wrote:

> My son is also on Zoloft and he is getting 12. 5 mg does that seem a like a

> high dose?

>

> La Toya

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[Guest guest]

My son is six years old and weighs about 39 pounds on 12.5 mg of Zoloft.

La Toya

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[Guest guest]

La Toya,

My son at age 8 (and at 78 pounds) was at his highest dose at...

1 50 mg pill alternating with 3/4 of a 50mg pill every other morning

we tried to up it to 1 50 mg pill per day but he could not tolerate that

dose.

Unfortunately, I don't know how to compare the doses as our kids weights are

so different.

Caroline

> On 8/23/03 7:58 AM, " THELION90@... " <THELION90@...> wrote:

> My son is six years old and weighs about 39 pounds on 12.5 mg of Zoloft.

>

> La Toya

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[Guest guest]

Hi ,

We just gave Garrett his 2nd shot of BayGam (IMGG) yesterday. (We

had to go to our hospital pharmacy to find it.... Longs doesn't

carry it.) I think it is too early to tell anything. It often

takes 3 shots for the children it helps, but as you know it doesn't

help all kids.

We doubled the Paxil to 2.5 mg on Friday. It is now 8:30 a.m. in

California, and he is still sleeping. Strange. I know SSRI's can

help with a person's sleep cycle (or destroy it totally!) so I hope

it is the former. We did hear him talking/crying out in his sleep

last night at one point, which is unusual for him. He stopped right

away, though. Hmmm... Does sleep talking occur in deep sleep? I

think I'll do a quick Internet search...

Best,

--- In , " Anagnostakos " <lsa588522@m...>

wrote:

> Dear ,

>

> Sounds like a great start on the SSRI!! We noticed hyperness

right away with , but after lowering the dose he settled out.

Hope all continues to go well with Garrett.

> By the way , how is Garrett doing on the IMGG ? Have you noticed

any effects yet or is it still to soon to tell ? Take care,

>

>

>

>

> ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

> Responsibility for the content of this message lies strictly with

> the original author, and is not necessarily endorsed by or the

> opinion of the Research Institute.

> ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

[Guest guest]

This is pretty scarey!

Rose

How soon do SSRI negatives begin?

Here's a recent article on this subject. Wanda

Children Taking Selective Serotonin Re-Uptake Inhibitors At Risk Of

Treatment-Emergent Psychiatric Adverse Events

J Child Adolescent Psychopharmacol 2003;13:2:143-152. " A systematic chart

review of the nature of psychiatric adverse events in children and

adolescents treated with selective serotonin reuptake inhibitors "

08/20/2003 10:27:56 AM

By Guy Furness

Children taking selective serotonin re-uptake inhibitors (SSRIs) are at risk

for developing psychiatric adverse events (PAEs), which emerge within a few

months of beginning treatment and resolve on discontinuation , according to

a US study. The systematic review of unselected medical records, led by

Wilens, MD, of Massachusetts General Hospital, Boston, United States

involved 82 children and adolescents (aged 3 to 18 years) with depression

or obsessive compulsive disorder (OCD), who had been treated

naturalistically with citalopram, fluoxetine, fluvoxamine, paroxetine or

sertraline. They were identified from a sample of all children consecutively

referred to the hospital's paediatric psychopharmacology clinic between 1993

and 2000. Of the 82 subjects, 18 (22%) experienced an SSRI

treatment-emergent PAE, with mood disturbance being the most common. The

researchers noted that their data, combined with the existing scientific

literature suggested that sleep disturbance and agitation were among the

most common. Behavioural activation was less common but tended to be more

serious, they said. The median time to onset of treatment-emergent PAEs was

91 days, and in 25% of children with PAEs, they emerged within 35 days. In

the study, SSRIs were discontinued when PAEs emerged. Half of PAEs had

resolved within 28 days of discontinuing SSRIs, and 75% had resolved within

49 days. The researchers commented: " The complete and rapid remission of the

PAEs upon SSRI discontinuation further supports the notion that the PAEs

were probably related to the SSRI. " It was also shown that patients whose

PAEs arose more rapidly had a more rapid resolution of the event after SSRI

discontinuation. Re-exposure to an SSRI following resolution of a PAE

resulted in another PAE occurring in 8 of 18 subjects. Noting that the study

had limitations, the researchers said that a better understanding of the

onset of PAEs relative to SSRIs was required but, until then, children

should be monitored for the onset of PAEs for the first few months of

treatment. There were no associations found between the development of a PAE

and either the child's sex; whether the child had OCD or depression;

presence of concurrent medication; or the type of SSRI being taken. The

researchers suggested that discussing with the families the potential for

adverse events when using SSRIs in children and adolescents was warranted

and, furthermore, might " enhance recognition and dampen the deleterious

impact of this idiosyncratic reaction. "

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=R

Retrieve & db=PubMed & dopt=Abstract & list_uids=1288690

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