Guest guest Posted September 15, 2004 Report Share Posted September 15, 2004 Hello all, My name is Jenn and I live in Lubbock. I have been diagnoised with having hypothyroidism with in the past couple of years. I joined an infertility group and one of the girls in there asked if I was part of a thyroid disorder group...she said her's was really helpful. Hints why I'm here. I have a question about meds. My doc (Lum) started me on Synthroid with no success so after changing the dosage several times he switched me to Cytomel. I don't seem to come accross many people who are on it especially at my dosage. I take 5mcg 3 times a day and my doc wants to up it to 4 times a day. It seems to be doing okay but I'm not sure that I would be able to tell the difference either way. It's been a long time since I have really felt good. I'm going to go and get a copy of my last labs so that maybe someone can help me sort through them. Any help would be great. Also as far as getting meds I started going to Sams. You don't have to be a member to go to their pharmacy and my Cytomel was actually cheaper to get it there than to use my insurance...I think they take insurance too but I'm not sure. Just a thought...it's could never hurt to call and ask. Talk to you all soon. Jenn Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 15, 2004 Report Share Posted September 15, 2004 I'm glad to hear that there is nothing unusual about the dosage...my mom of course thought it sounded like a lot so I figured any one that had first hand experience or knowledge would be able to help. All he has prescribed me is Cytomel, I don't feel like it's helping very much at all but he said that it has changed my levels. I don't know for sure. I'll send my labs when I get them. Thanks for the help and the welcome. Jenn Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 15, 2004 Report Share Posted September 15, 2004 There could be a few things happening. first Synthroid is only one ot the 7 thyroid hormones that the healthy thryoid makes. It is the thyroid hormone T4. T4 is relatively inactive and must be converted by the body to the other thyroid hormones. T3 and T2 are the most metabolically active thyroid hormones that do the most to regulate energy in the body. Many people have a problem converting T4 to these other hormones and therefore do not get much benifit from Synthroid. The other thryoid hormones are important in estrogen function and hormone status of the other hormones, such as progesterone and testosterone. T3, and T2 work to regulate how estrogen works in the body and estrogen receptor density. Armour thyroid, a natural thryoid, contains all the thryoid hormones that the thyroid makes and is in close to the proper proportions for humans. This might work better for you to get your hormone status right. If hypothyroidism is not properly treated, estrogen goes way too high and progesterone is depleted. The effect of this is to prevent the retaining of the fetus in the uterus. Progesterone in high levels is needed to keep the pregnancy and for the fetus to get sufficient oxygen. The other thing that might be happening is that I suspect your replacement doses have been way too low. Today, thryoid replacment doses are 1/3 of what they were before about 1975. this is due to heavy reliance on the TSH test, which can be useless in people with pituitary dysfunction (about 40% of thyroid patients) and auto- immune thryoid disease. In both cases, measuring TSH very often will not give an accurate reflection of true thyroid status. It would be much better to measure Free T3 and Free T4. 5 mcg of cytomel 4 times a day is not very much. I was on all T3 replacement (Cytomel)and I used 90 mcg a day. It took this much to get my metabolic rate and body temperatures up to the proper level. This is actually a common dose for those for all T3 replacement and is at the low end of average. All T3 can also interfere with fertility in my opinion. This is because it pushes the body toward more androgen production. Finally, The other thing that could be interfering with fertility is that your adrenal output is too low. Adrenal fatigue or hypofunction is very common in hypothryoidism and if you are undertreated for your thyroid condition, then adrenal outpout will be low. The adrenals are affected by thyroid status. If thyroid is low, adrenal output is also low. I would really recommend that you read McK Jefferies book " Safe Uses of Cortisol " . In it he discusses many case histories of infertility and thyroid and adrenal deficiency. You might greatly benifit from low dose cortisol treatment. Cortisol and the other adrenal hormones are crucial to proper reproductive cycling and hormone balance needed for pregnancy. When adrenal ouput is low, cycles can be nonexistant or very irratic, DHEA, progesterone, estradiol, testosterone, blood sugar and many other hormonal conditions are affected. Blood sugar can go too low for a good pregnancy. Have you ever tried using your temperature to adjust your thryoid dose? This is an excellent way to get a dose that gets your metabolic rate up to the proper level. I would suggest that you switch to Armour thyroid and slowly adjust your dose up every two weeks to a month untill your body temperatures average 98.6. Body temperature is a measure of metabolic rate, which is controlled by thryoid and adrenal output. To read how to do this go to Dr. Rind's page at: http://www.drrind.com/tempgraph.asp If it were me, I would also add 20 mg of cortisol a day, taken 4 times a day in even doses. The body makes 35 to 40 mg a day, so you cannot overdose on 20. Anything that you take less than 40 your own adrenals will drop by that amount if needed to keep blood levels proper. Read Jeffries book to see how to do this and his discussion on pregnancy and low dose cortisol. The average final dose of Armour medication for most people to get relief from symptoms is 3-5 grains. The healthy thryoid makes 4-1/2 to 5 grains Armour equivlelent a day or 333 mcg to 370 mcg of Synthroid equivlelent and day. In the older studies done with Synthroid, which was new at the time, they found that it took 300 to 400 mcg of Synthroid for patients to get relief from hypothryoid symptoms. This totally supressed TSH. This is because synthroid results in high levels of T4 in the blood to get proper levels of T3. T4 is very suppressive of TSH. Later is was decided that patient feelings about their status was not right and that the TSH test reflected the real truth. Then doses dropped to 1/3 of what they are today. You can get cortisol in IsoCort, an over the counter medication, that contains 2.5mg of cortisol per pellet, or you can order Nutri+Meds adrenal. I do not know the dose. You could also go to http://thyroid.about.com/ and look through the list of top docs to find one that prescribes Armour or go to the Armour site and find a doc. http://www.armourthyroid.com/. You might also consider using a D.O. instead of an endocrinologist. These are doctors that tend to use natural hormone replacements and to test hormone levels mor thoroughly. You can also treat yourself for you thyroid condition using temperature and symptoms by ordering Armour from pharmacies outside the country. Many of the top docs use low dose cortisol replacement if neccessary. Other older studies looking at pregnancy and low thryoid have found that it is better for the mother to be a little hyperthryoid than hyothryoid. Hypothyroidism is bad for the development of the fetus and greatly increases risk of miscarriage. Whereas mild hyperthryoidism does not seem to be harmful. Tish Quote Link to comment Share on other sites More sharing options...
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