Guest guest Posted April 2, 2005 Report Share Posted April 2, 2005 Mycoplasma: Its hidden role in rheumatoid arthritis and other clinical syndromes - Quantum Medicine Update by Jr. Yanick, Townsend Letter for Doctors and Patients Mycoplasma may serve as a cofactor that along with biological and/or chemical stressors can induce cytokines and other immune abnormalities found in rheumatoid arthritis (RA). The overuse of antibiotics has caused widespread bacterial resistance to antibiotics and has contributed to the development of new strains of disease that are not treatable with current antibiotics. These stealth infections pose a continuing threat to human health and may be implicated as cofactors in a number of clinical syndromes. Research has implicated certain mycoplasma species as a causative factor in chronic fatigue syndrome (CFS), RA and gulf war syndrome (GWS) (1-4) In one study, forty-nine of sixty RA subjects had evidence of mycoplasma infections that were documented by multiplex polymerase chain reaction (PCR). Unlike other lab tests which fail to detect mycoplasma, multiplex PCR assays allow for unmatched clinical accuracy in the identification and differentiation of mycoplasma species. Because RA, CFS, and GWS are characterized by overlapping symptoms, researchers are gathering more and more evidence that points to stealth infections as the missing link to effective treatment in these disorders. Rather than treating RA and other forms of arthritis with anti-inflammatory drugs that are poorly researched and not safe for long-term use, more clinical efforts need to be made in identifying stealth infections using multiplex PCR and quantum meridian stress measurement (QMSM) techniques. Since mycoplasma infections are found at significantly higher rates in RA, effective treatment should be aimed at immunomodulation therapies that help the body uncover and destroy stealth infections. Members of the genus mycoplasma lack cell walls, and like viruses, are capable of self-replication. Microplasma fermentans colonizes human mucosal tissues and under certain conditions can invade the host cells or fuse with CD4 cells, inducing the production of proinflammatory cytokines such as IL-6 and tumor necrosis factor alpha. (6-7) Indeed, the occurrence of mycoplasma and ureaplasma species in joint tissues of RA and other forms of arthritis provides convincing evidence that mycoplasma is a significant cofactor, among other stressors, that precipitates the symptomatology of RA. (8-12) Yet, just as it took decades for medicine to realize that helicobacter pylori caused peptic ulcers, there continues to be a lag time in the acceptable treatment of mycoplasma and stealth infections in clinical cases of arthritis. (13) If infection is a causative agent in arthritis, what constitutes effective treatment? In two independent, randomized trials, RA patients were treated with lOOmg of oral doxycycine or a placebo twice daily for 26 weeks. The results demonstrated a greater than 75% improvement in arthritic symptoms in patients taking the drug versus a placebo. (14,15) While doxycycline or minocycline may be life-saving in advanced cases of mycoplasma, solving the problem of infection requires more than the use of antibiotics. Furthermore, many microbes now defy antibiotics that once killed them. And, the use of antibiotics causes resistant microbes, viruses, or fungal infections to replicate, grow and multiply. In many cases, the overuse of antibiotics has resulted in the spread of hepatitis, cytomegalovirus, herpes viruses, parasites, and many other dreadful microbes. The lifestyles of patients with mycoplasma infection lay the foundation for opportunistic infections to flourish and conquer the body. Irradiated foods, genetically-modified foods, radiation, and chemical stressors trigger clusters of mutations that interfere with DNA stability and reduce the function and regeneratory capacity of lymphocytes. QMSA techniques provide a window into the body to quickly assess each individual's unique stress patterns between toxins, parasites, parasitic toxins, bacteria, mycoses, viruses and metabolism. Therefore, when stress is reduced, one may expect the immune system to function with greater efficiency. In RA patients, it is common for impregnated toxins and mutated proteins to congest and damage the body's lymph nodes causing a functional impairment in the immune system. This deposition of toxins extends itself into the joints and allows opportunistic infections to grow and flourish while continually damaging the immune system and extracellular matrix interface to the energetic system of healing. As such, cold photon scalar therapies, advanced detoxification protocols and immunomodulation therapies are necessary to reduce toxin and microbial stressors and to help the body regain a greater range of immunological functions. Reestablishing the Superhighway in Our Genes Genes send light/electrical signals to one another through a DNA information " superhighway. " Biochemists are amazed at the distance over which these signals can travel. (16,17) Toxin deposits seem to limit the distance these signals can travel and/or stops these signals from reaching their destination, thereby causing a deficit in biocommunication. Many physicists feel that these toxins are " light scramblers " in that they cause chaos in the DNA's signaling system which includes the extracellular matrix and its interface with the human energy system. In RA patients, enhancing the immune system's ability to patrol, enforce, and attack invading microbes with greater operational complexity requires understanding the sub-molecular dynamics of DNA in the orchestration of the body's defense and repair routines. In other words, while we understand the negative repercussions of oxidative stress at the molecular level, it's equally important to understand how it reduces the repair capacity of DNA at the quantum level. Therefore, re-establishing quantum coherence -- a state of immune competence with adequate DNA repair enzymes -- may provide the best treatment in infectious disease. The best way to understand quantum coherence and DNA is to look at how it works in the salamander and pondworm. When a salamander loses a leg torn off by a predator, it simply regrows a new one. When a pondworm is chopped in half, each half regrows into a whole, complete worm. How does the worm's body know where to reassemble new organs when half of them are missing? These miraculous powers of healing are inherent in DNA. For humans, these genetic cascades of DNA-generated biophoton energies are the most powerful when we are embryos. Yet, as we grow older and enter the world our immune systems immediately engage in warfare against pathogens, chemicals, and other stressors. For some reason, over engaging our immune systems, has the effect of repressing healing networks within our DNA. Plausible evidence exists to support the idea that defining and eliminating these stressors may be the first step in uncovering the missing links to feats of regeneration found in species like the salamander or pondworm. These DNA-guided signals flow throughout the body with awe-inspiring speed. Stately simply, the magnitude of DNA's coherence, determines the course of our health. For example, when there is quantum coherence, the magnitude of inner healing is so gigantic that it renders even the best of minds helpless for exploring the endless boundaries of its power. Can we " click on " the genetic switches that power up our capacity to heal and regenerate? Unfortunately, more research is needed to answer this question. The problem is that most current scientific study of the human body delves deeply into the chemistry and molecular nature of cells with very little emphasis on how healing functions can be nourished, how they can be expanded, or how its faculties can be used more efficiently. During the past 80 years of our existence these healing powers have been shrouded behind ignorance and myths, or principles held sacred by modern medicine or assumed trivial by the medical branches of science. Yet a wide spectrum of non- pharmaceutical/medical scientific research coupled with ancient wisdom, documents profound insights into our nature and ability to evoke self-healing and regeneration. From time to time modern medicine and science express opinions about the nature of healing. None of these theories account for the true essence of healing. Behind the philosophical pronouncements on the essence of healing lies a chaotic jumble of fragmented and unexplored half-guesses about how the greatest healing power within our bodies works or doesn't work. And, when medical experts observe healing from natural methods, they typically dismiss it as the " placebo effect. " Yet when this healing is observed on the very same patients who failed to respond to their best efforts, one has to question: where was the placebo effect in all their patient- doctor interactions? Obviously, when a patient who has consulted unsuccessfully with six or more doctors for the same condition over a period of ten years, suddenly experiences healing after visiting an alternative practitioner, there's more than a placebo effect involved. Buffeted by the whims of political and industrial economics, these researchers hesitate to probe the natural healing dimension of the body. This has been an unfortunate barrier to understanding how to nurture, strengthen, and fulfill the body's optimal potential for healing. The complete eradication of mycoplasmas from the body requires an intact, functional immune system working in concert with a DNA repair system and the human energy system. In these cases, it is of utmost importance to support Phase 1,11 and III liver detoxification systems and the kidneys using immunomodulation techniques to augment the body's army of immune cells that identify, tag, poison, blast, and consume microbes that invade the body's biological turf. Indeed, the augmentation of lymphocytes with herbal medicine is well known. (18) Clinical Research with Mycoplasma Infections Our preliminary observations with mycoplasma reveals that it usually underlies sensory nerve root inflammations and allied conditions caused by herpes-type viruses. It appears to be the deepest infection in the nervous system in chronically ill patients and the underlying cause or stressor in recurrent herpes-type viral infections. Yet, despite its wide prevalence, clinicians have ignored a possible role for mycoplasma in a wide spectrum of clinical syndromes. It seems that the thread that ties mycoplasma to RA and other degenerative diseases is stressed body defenses caused by a reduction in DNA-guided repair mechanisms and immunological defenses. Moreover, hidden parasite infections and parasitic toxins may be able to switch off the host's immune system, allowing mycoplasma to spread rapidly throughout the body. It appears that mycoplasma, like the herpes virus, harbors itself in the tube-like fibers of the nervous system which serves as a hidden tunnel for this infection to spread throughout the body without being detected by immune surveillance. With QMSM methods of electrodermal biofeedback, a practitioner can quickly identify and observe how these microbes stress the body and where they are predominantly located. Moreover, the sequence or layering of these immune-stressing microbes can be observed with a reasonable degree of accuracy (depending on the test system and practitioner) and confirmed by lab tests. In an overwhelming majority of clinical cases, we can trace these stressors back to old, unresolved dental foci such as septic root canals or ostitis in old tooth extraction sites. Our clinical efforts against mycoplasma have included the use of a blend of hyssop (whole herb concentrate; not extract) containing the full spectrum of naturally- occurring caravacrol, thymol, and other phytochemicals in synergistic combinations with other herbs and nutrients. The antimicrobial, anti-viral and nervine properties and cleansing effect of hyssop are extraordinary when combined with appropriate cofactors and transporters. (19-21) Most importantly, the oral use of the essential oils of oregano, rosemary, clove, DL limonene, and fermented adaptogenic herbs and citrus seed extracts may provide powerful phytomedicines against stealth infections, like mycoplasma. However, since mycoplasma commonly underlies viral infections, immunomodulation strategies against viral pathogens or hidden parasites may need to be employed for best results. These immunomodulation therapies are designed to capitalize on the immune system's vastly superior qualities to fight viral infections and account for the web-like int eraction and interpenetration of the immune system with the human energy system. In previous columns, I have discussed the components of such an immune enhancement program in detail. (22- 23) Reestablishing the extraordinary complexity of the immune system at the quantum level of biophoton light communication is of primary importance in helping to alleviate the suffering of RA patients. While the anecdotal and scientific evidence discussed in this article are astute and insightful, detailed, carefully-controlled studies that uncover the clinical manifestations of mycoplasma and its interaction with parasites and other emerging microbes are warranted. (24) Since these studies reveal that mycoplasma is a cofactor, it should be assessed and treated before anti- inflammatory and immunosuppressive drugs are employed. Clearly, eliminating the pain and inflammation of arthritis requires a better understanding of how multiple biological and chemical stressors interact with mycoplasma and with the immune system to induce inflammation. The major therapeutic advances will be with phytonutrients and mycelial mushrooms that augment immune functions in a multidirectional manner while chemical stressors that indu ce DNA instability are properly detoxified from the body. Finally, The Brucellosis Triangle documents how biological warfare research between 1942 to the present time has resulted in more deadly and infectious forms of mycoplasma. (25-27) Because of its affinity with the nervous system, detecting and properly treating mycoplasma will require clinical approaches that target and cleanse the nervous system. Toxicity of the nervous system, especially with heavy metals, serves as an impetus for mycoplasma to withdraw energy from the neurons and paralyze the immune system. Since ordinary blood and tissue tests do not reveal the presence of mycoplasma infection, physicians should employ multiplex PCR to detect this infectious agent and make some attempt to categorize the strata of microbial stressors that interfere with immunological functions in chronically ill patients. (29) References (1.) Vojdani A et al Detection of Mycoplasma genus and Mycoplasma fermentans by PCR in patients with chronic fatigue syndrome. FEMS Immunology & Medical Microbiology 1998 22355-65. (2.) Schaeverbeke T et al Systematic detection of mycoplasma by culture and PCR in 209 synovial fluid samples. British J Rheumat 1997; 36:310-14. (3.) Nicholson GL at al Diagnosis and treatment of Mycoplasmal infections in Persian Gulf war Illness-CHIDS Patients. Int; J Occupational Medicine, Immunology, and Toxicology 1996;5(1):69-78. (4.) Vojdani A Franco AR Multiplex PCR for the detection of Mycoplasma fermentans, M. hominis, and M. penetrans in Patients with Chronic Fatigue Syndrome, Fibromyalgia, Rheumatoid Arthritis, and Gulf Syndrome. Microbiology 199; 187-99. (5.) Gerard HC et al Frequency of apolipoprotien E allele types in patients with Chlamydia-associated arthritis and other arthritides, 1998; Microbial Pathogenesis 26: 35-43. (6.) Dimitrov DS et al Mycoplasma fermentans cells are able to fuse with T- lymphocytes. Clin Inf Dis 1993: 17(1):305-08. (7.) Mulhradt PF et al Mycoplasma fermentans leads to in vitro IL-1, IL-6, tumor necrosis factor and prostaglandin product and is pyrogenic in rabbits. Inf Immun 1991 59:3969-74. (8.) MH Recovery of mycoplasma from rheumatoid synovial fluid. In Third Pfizer Symposium on Rheumotic Diseases, 1966: Edinburgh University Press, 161- 89. (9.) Washburn, LR et al Chronic arthritis of rabbits induced by mycoplasma. Clinical, microbiologic, and histological features. Arthritis Rheum 1960 23:825-36. (10.) Burdge DR et al Septic arthritis due to dual infections with Mycoplasma hominis and Ureaplasma urealyticym. J of Rheu 1988 15: 366-71. (11.) Posnett DN et al Interaction of Mycoplasma arthritidis superantigen with human T-cells. Clin Inf Dis 1993 17:170-75. (12.) Behar SM et al Mechanisms of autoimmune disease induction: the role of the immune response to microbial pathogens. Arth & Rheu 1995 38:458-76. (13.) Ewald, PW Plaque Time 2000; The Free Press, NY. (14.) - D Mycoplasma in rheumatoid arthritis and other human arthritides. J Clin Path 1996: 49:762-82. (15.) Cohen MA et al In vitro susceptibilities of Mycoplasma pneumoniae, bominis and ureaplasma urealyticum to clinafloxacin, PD 131628, ciprofloxacin and comparator drugs. J Antimicrob Chemother 1997: 40:308-9. (16.) Barton J et al Chem & Biolol 1999, 2:85. (17.) Coghlan A Electric DNA. New Scientist 1999: 2: 19. (18.) Greunwald J et al PDR for Herbal Medicines, 1998, Medical Economics Company, New Jersey. (19.) Yanick P. Meridian/Organ Nutraceutic Resonant Complexes: New Hope for Chronically-Sick Individuals. 2000, May Townsend Letter for-Doctors & Patients; 136-39. (20.) Yanick, P. Boosting Nutrient Uptake in Chronic Illness, Dec 2000, Townsend Letter for Doctors & Patients. (21.) Yanick, P. Food Supplement Benefits and Risks in Carcinogenesis: Part I, Oct 2001. Townsend Letter for Doctors & Patients. (22.) Yanick, P Immune System Protection against Bioterrorism. Dec 2001. Townsend Letter for Doctors & Patients. (23.) Yanick, P Novel Antiviral Strategies against Biotorrorist Attacks. Feb-March 2002. Townsend Letter for Doctors & Patients. (24.) Ewald W Guarding against the most dangerous emerging pathegens: Insights from evolutionary biology. 1996. Emerging Infectious Diseases 2:245-57. (25.) DW & WLC The Brucellasis Triangle 1998: The Chelmsford Publishers, Canada. (26.) Pathogenic Mycoplasma. US Patent No. 5, 242,820 issued September 7, 1993. (27.) Howell at al Acute Brucellosis among laboratory workers. 1948 New England Journal of Medicine 236:741. (28.) Colmonero et al Complications associated with brucellosis melitensis infection: A study of 530 cases, 1996; Medicine 75:4. (29.) Vojdani, A. Immunosciences Lab Manual, 2000. Quote Link to comment Share on other sites More sharing options...
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