Re: Olanzapine?

[Guest guest]

It's pretty stupid to drug someone when there isn't a problem. Also, it's dangerous to do, and should never be taken lightly.

[Guest guest]

Only one drug has been approved by the US Food and Drug Administration

for use specifically for autism, and that is Risperdone.

Separate studies indicate that because the nervous systems and brain

structures in autistics may be different than those of non-autistics,

drugs that may work for non-autistics may actually be harmful to

autistics or they may not work at all.

Why is this medication being prescribed?

Administrator

Hello all. My brother, Rob, diagnosed Asperger's in '81, has been

" medicated " (read: drugged) with a very powerful neuroleptic,

Olanzapine, for at least the past decade. Always suspicious of

" prescribed " solutions by " professionals " , I'd like to hear others'

views on pharmaceutical interventions for Aspies & others w/ autistic

spectrum disorders. Thanks.

Wondering aloud,

Anadæ

[Guest guest]

Yeesh, Professor Zoologist, that's just plain nuts! The very

pharmaceutical compound that you mention here WAS prescribed to my

Aspie brother. He was taken off of it due to its wonderful influence

of conveying to him a severe case of tardive dyskinesia, which is,

for the uninitiated in pharmaceuticalese jargon, an involuntary extra-

pyramidal contraindication wherein the " consumer " goes through every

conceiveable facial expression in rapid succession. Not the kind of

ability one would want to have to contend with on a daily basis, I

daresay!

So, my shrink, after disclosing his sentiment to me on that

particular FDA approved compound, and I quote, " Risperdal?! I can't

even BELIEVE that they're still prescribing people that! Tell him to

go on this instead. " Well, the 'instead' prescription was the

neuroleptic clozapine, which you must know has yet another adverse

attribute of cutting the individual's lymphocyte production to far

below the safety zone. I'm tellin' ya! If it ain't one thing, it's

another!

Eventually, Rob was pulled off of that despite the fact that he

suffered no negative percussions of having his immune system

dangerously suppressed. And THAT, my friend, is how he ended up on

Zyprexa. The only drawback that THAT has had is endowing him with

extreme drowsiness & prolonging his sleep cycle.

Hey, at least he's a most excellent drummer in a rock band once

again. They even just put their first CD out. Thanks for your

comments, . I really needed the support.

Happy to be here,

Anadæ

>

> Hello all. My brother, Rob, diagnosed Asperger's in '81, has been

> " medicated " (read: drugged) with a very powerful neuroleptic,

> Olanzapine, for at least the past decade. Always suspicious of

> " prescribed " solutions by " professionals " , I'd like to hear others'

> views on pharmaceutical interventions for Aspies & others w/

autistic

> spectrum disorders. Thanks.

>

> Wondering aloud,

> Anadæ

>

[Guest guest]

>

>

>

Olanzapine

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Olanzapine

Systematic (IUPAC) name

2-methyl-4-(4-methyl-1-piperazinyl)-

10H-thieno[2,3-b][1,5]benzodiazepine

Identifiers

CAS number 132539-06-1

ATC code N05AH03

PubChem 4585

DrugBank APRD00138

Chemical data

Formula C17H20N4S

Mol. mass 312.439

SMILES eMolecules & PubChem

Pharmacokinetic data

Bioavailability ?

Metabolism Hepatic

Half life 21–54 hours

Excretion ?

Therapeutic considerations

Pregnancy cat. C

Legal status Prescription only

Routes oral, intramuscular

Olanzapine (Zyprexa, Zyprexa Zydis, Zalasta, Zolafren, Olzapin, or in

combination with fluoxetine Symbyax) is an atypical antipsychotic,

approved by the FDA for the treatment of: schizophrenia on 1996-09-30;

[1] depressive episodes associated with bipolar disorder, as part of

the Symbyax formulation, on 2003-12-24;[2] acute manic episodes and

maintenance treatment in bipolar disorder on 2004-01-14.[3] Off-label

uses are listed below.

The olanzapine formulations are manufactured and marketed by the

pharmaceutical company Eli Lilly and Company, whose patent for

olanzapine proper expires in 2011.

> Eventually, Rob was pulled off of that despite the fact that he

> suffered no negative percussions of having his immune system

> dangerously suppressed. And THAT, my friend, is how he ended up on

> Zyprexa. The only drawback that THAT has had is endowing him with

> extreme drowsiness & prolonging his sleep cycle.

>

> Hey, at least he's a most excellent drummer in a rock band once

> again. They even just put their first CD out. Thanks for your

> comments, . I really needed the support.

>

> Happy to be here,

> Anadæ

>

It seems Zeprexa is exacly the same drug. Hmmmmm Messing with you

guys they are. I look up everything that gets perscribed these days,

look up muliple references too.

[Guest guest]

I was told Prozac was a short term med' when I was initially put on it

(am not on it now btw) and yet they left me on it for years and kept

upping the dose - I finally got off it with doctors permission and even

doing such slowly had a lot of nasty side affects just coming off it.

Also years later someone mentioned a connection between Prozac and

bones been weaker. Before I went on Prozac I never broke any bones to

my knowledge, but I have broken bones in my feet quite a few times

since.

The doctor did once try putting me on Prozac, or something in the

Prozac family since and I had a very bad re-action to it, in fact most

of the anti-depressant and anti anxiety med's they have tried on me

seem to have bad side affects.

Still saying all of the above I have been getting increasingly stressed

recently, which I think I have had ongoing stress for sometime which

inevitably leads to depression, so unless things improve in this area

soon I may consider taking med's again, but I really hope I don't have

to.

>

> I was on Paxil for many years because of my anxiety issues. It turns

out you

> were only supposed to be on it for short periods of time. One of the

> potential side effects was eye damage and I think it might have

damaged one of my

> eyes, if not both. No way to prove it though.

>

>

[Guest guest]

the reaction you have had to most of the meds you have been on is in

keeping with that experiences by many (but not all) people on the

spectrum. I am a member of a parents's forum that seems pretty med

happy. It usually takes about 6 months after putting their autistic

kids on meds and then they start reporting increased depression, angry

and violent outbursts, suicidal behavior, and general side effects

commonly associated with the drugs.

Given that many autistics are hyoer and hypo sensitive, and gene

mapping has determined enough structural variations to render the use

of some of these drugs harmful, one wonders why physicans would even

consider medication for autistics unless absolutely necessary.

The parents, who are of course overly eager to squash the souls of

their autistic children, enthusiastically ask for different drugs

whilst never stopping to think that it may be their own bad parenting

which is causing their autistic children to act out in the first place.

Administrator

I was told Prozac was a short term med' when I was initially put on it

(am not on it now btw) and yet they left me on it for years and kept

upping the dose - I finally got off it with doctors permission and even

doing such slowly had a lot of nasty side affects just coming off it.

Also years later someone mentioned a connection between Prozac and

bones been weaker. Before I went on Prozac I never broke any bones to

my knowledge, but I have broken bones in my feet quite a few times

since.

The doctor did once try putting me on Prozac, or something in the

Prozac family since and I had a very bad re-action to it, in fact most

of the anti-depressant and anti anxiety med's they have tried on me

seem to have bad side affects.

[Guest guest]

This happened with Paxil too. If I was late on a dose, my head would really start to ache and I'd get as wired as if I had drunk a gallon of Espresso. Eventually it got to the point where the Paxil was CAUSING anxiety and panic attacks rather than preventing them. It took me a while to figure that bit out, but I eventually realized that it the attacks weren't starting before I took the pills, but happened afterwards. The doctor said that couldn't happen and want to change the dosage or put me on something else. I didn't do either and went off meds altogether. It hasn't been easy and depression is still an issue, but I just put up with it.

Whatever you do, do not let your doctor put you on Effexor for the depression and stress. I am currently taking Effexor and it not only was hard to start taking, but every time that a dose is accidentally skipped I have withdrawal symptoms, and not to mention that I try to take it at the same time every day, but even going 24 hours will lead to minor withdrawal (like headaches and nausea). Psssst...Have you heard the news? There's a new fashion blog, plus the latest fall trends and hair styles at StyleList.com.

[Guest guest]

Hi , "Still saying all of the above I have been getting increasingly stressed

recently, which I think I have had ongoing stress for sometime which

inevitably leads to depression, so unless things improve in this area

soon I may consider taking med's again, but I really hope I don't have

to."Whatever you do, do not let your doctor put you on Effexor for the depression and stress. I am currently taking Effexor and it not only was hard to start taking, but every time that a dose is accidentally skipped I have withdrawal symptoms, and not to mention that I try to take it at the same time every day, but even going 24 hours will lead to minor withdrawal (like headaches and nausea). I read all the warnings ahead of time and even people's blogs about whatever the doctor prescribes before I start taking it, but I never would have imagined that it was this bad. Unless it is your last resort stay away from this. (On a side not I have used Zoloft and Lexapro previously which although they did not help me, I know others who think that those prescriptions are a God-send).Hope things get better so the stress does not get to you.Sincerely,

[Guest guest]

> Whatever you do, do not let your doctor put you on Effexor for the

depression and stress. 

I took Effexor also for a time but it caused me manic episodes. I too

had odd side effects when I began taking it and coming off it as

well. Visual disturbances were very unnerving.

Kim

[Guest guest]

" (On a side note I have used Zoloft and Lexapro previously which

although they did not help me, I know others who think that those

prescriptions are a God-send). "

Zoloft made my sister (diagnosed AS) suicidal and more depressed. She

is on Paxil now and is less suicidal, and slightly less depressed than

she was to start with.

Administrator

[Guest guest]

" Eventually it got to the point where the Paxil was CAUSING anxiety and

panic attacks rather than preventing them. "

Personally, I think this is happening with my sister also, although she

claims the Paxil is making her slightly less depressed.

Administrator

[Guest guest]

I was on Zoloft for a short time. Like your sister, it made me really depressed and manic. Stopped taking it after about a week.

Its amazing how all these drugs that are supposed to help may work for one thing but can hurt you in so many other ways. I'm surprised drug sales aren't being clobbered by the ads the companies spend so much more money on than actual research. The long list of warnings at the end would scare me off most of them.

In a message dated 9/9/2008 2:15:15 A.M. Eastern Daylight Time, no_reply writes:

Zoloft made my sister (diagnosed AS) suicidal and more depressed. She is on Paxil now and is less suicidal, and slightly less depressed than she was to start with.AdministratorPsssst...Have you heard the news? There's a new fashion blog, plus the latest fall trends and hair styles at StyleList.com.