Guest guest Posted December 20, 2004 Report Share Posted December 20, 2004 Thank you Marilyn for this notice! This is actually one of the drugs my RD wanted to try with my pregnancy! Which really doesn't make sense - considering my OB said I couldn't have anything like Aspirin or Aleve! Thank God for this group! > U.S. government halts naproxen Alzheimer trials > > Associated Press > > WASHINGTON — A U.S. government study testing whether Celebrex or > naproxen would reduce the risk of Alzheimer's disease was halted > Monday after researchers noted an increase in heart attack and stroke > among participants who were taking naproxen, an over-the-counter pain > reliever on the market for nearly 30 years. > > Officials at the National Institutes of Health said the study was > stopped after three years when it was noticed patients taking > naproxen, sold under the brand name Aleve, had a 50-per-cent greater > incidence of cardiovascular events -- heart attack or stroke -- than > patients taking placebo. > > Another factor, officials said, was the announcement last week that > advertising for Celebrex was being halted after a study found high > doses of the drug were associated with an increase in heart attack > risk. Data from the Alzheimer's study, however, did not indicate an > increased risk for heart attack or stroke. > > Celebrex and naproxen are both pain relievers commonly used to treat > arthritis. Naproxen has been approved for sale in the United States, > first as a prescription and then as an over-the-counter drug, since > 1976. > > Efforts to obtain reaction Monday night produced no answers at phone > numbers for Bayer Healthcare, the maker of Aleve, a popular version of > naproxen. > > Dr. Kweder of the U.S. Food and Drug Administration said the > NIH study is the first to show naproxen might increase the risk of > heart attack or stroke. > > " We agree that this is confusing,'' she said. > > The FDA will closely evaluate the findings from the NIH study, said > Kweder, but that no new regulatory action with naproxen is expected > within the next few days. > > She said patients who routinely take naproxen should follow the drug > directions carefully, including the instruction not to take it for > more than 10 days and to consult a doctor if there continues to be > pain. > > The Alzheimer's disease study was being conducted by the National > Institute on Aging, an arm of the NIH. It called for 2,500 patients, > aged 70 or older and who had a family history of Alzheimer's, to take > either Celebrex, naproxen or placebo. > > The group was divided and each division, or arm, was assigned to > receive one of the drugs or placebo. The drugs were blinded, which > means the patients did not know which medication they were taking. > > The goal was to determine if the pain-relieving drugs lowered the risk > of developing Alzheimer's disease. The study started three years ago > and was to continue for a few more years. Officials said the patients > in the study will be monitored for developing Alzheimer's but will not > be given the test drugs. > > Dr. Elias Zerhouni, director of the National Institutes of Health, > said the study linking heart attack to Celebrex last week was a major > factor in deciding to suspend the Alzheimer's study. > > He said there was a question whether patients in the study would > continue to take their medicine since they knew they might be taking > Celebrex. > > Suspending the study, Zerhouni said, " is the prudent thing to do.'' > > Breitner of the Veterans Affairs medical facility in Seattle and > the University of Washington, an investigator in the trial, said only > preliminary data is available. But it suggests about 70 patients of > the 2,500 suffered stroke or heart attack, including 23 deaths and > there were about 50 per cent more such events in the naproxen arm of > the study than in the placebo division. > > > Visit the Still's Disease Message Board > http://disc.server.com/Indices/148599.html > > The materials and information contained in this message are not > intended to replace the services of a trained health professional or > to be a substitute for medical advice of physicians and/or other > health care professionals. The International Still's Disease > Foundation is not engaged in rendering medical or professional medical > services. You should consult your physician on specific medical > questions, particularly in matters requiring diagnosis or medical > attention. The International Still's Disease Foundation makes no > representations or warranties with respect to any treatment, action, > application, medication or preparation by any person following the > information offered or provided within this support form. > > ion by any person following the information offered or provided > within this support form. > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 21, 2004 Report Share Posted December 21, 2004 Hi gang, I just wanted to make a note on the Aleve and naproxen warning. I am a 24/7 CNN watcher and the study they did and announced. The study was done on people 70 and over and that were using celebrex .So it was a study of persons being 70+and they were also on celebrex and they took at least 2 Aleve twice a day for three years. A very silly study if they were going to use a study group they should have used a group that would reflect on the average person.I"m sure they will do much more soon. But I wouldn't panic about Aleve.They are saying don/t use for more then 10 days without talking to your doc. Aloha Dottie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 21, 2004 Report Share Posted December 21, 2004 Yes, I was watching the news last night when they broke with this story. I am a person who takes Aleve sometimes when I am in between times for my Lortab and MSContin. It works for me. The newscaster also announced that there maybe a possibility that Ibuprofen maybe a target next too. I think we are living in a world that has become completely silly with regards to pharmaceuticals. This drug will do this to you and that drug will do that to you. Before long, we may hear that aspirin is bad too. All of these episodes remind me of several years ago, when grilling was considered bad due to carcinogens. If I remember correctly, we were all supposed to stop flipping hamburgers on the grill. LOL. Bottom line for this woman, I'm not stopping the use of Aleve. Like you said Dottie, no longer than 10 days at a time. I don't take it that often, but it is nice to have around for those days where you need that extra push to get you through. I wonder what they will come up with next. LOL. Take care. Much love, Terry Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 21, 2004 Report Share Posted December 21, 2004 Hi Marilyn, I saw that on the news last night and I couldn't believe it! The Naproxen (Aleve) was what I had switched to from Celebrex. Now what? My husband says I should try herbal, but I just don't know. I don't think he really understands the pain. What does everyone else think? Post your free ad now! Yahoo! Canada Personals Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 21, 2004 Report Share Posted December 21, 2004 The Celebrex study was on people taking HIGH doses in the neighborhood of 800mg a day. I was taking two of the 200mg Celebrex a day and am now just taking the one 200mg Celebrex capsul a day. I am planning to continue taking the one 200mg Celebrex for a while. I do not understand how come they would be giving such a high dose anyway of the 800mg a day or more. I think I read that these dose's were given to cancer patients. My Rheumy told me anyway that the Celebrex just treats the symptoms and not the disease. But has been a pretty darn good low grade pain pill for me anyway. When the real pain hits nothing works except the narcotics anyway. Re: Naproxen Warning Hi Marilyn, I saw that on the news last night and I couldn't believe it! The Naproxen (Aleve) was what I had switched to from Celebrex. Now what? My husband says I should try herbal, but I just don't know. I don't think he really understands the pain. What does everyone else think? Post your free ad now! Yahoo! Canada PersonalsVisit the Still's Disease Message Boardhttp://disc.server.com/Indices/148599.htmlThe materials and information contained in this message are not intended to replace the services of a trained health professional or to be a substitute for medical advice of physicians and/or other health care professionals. The International Still's Disease Foundation is not engaged in rendering medical or professional medical services. You should consult your physician on specific medical questions, particularly in matters requiring diagnosis or medical attention. The International Still's Disease Foundation makes no representations or warranties with respect to any treatment, action, application, medication or preparation by any person following the information offered or provided within this support form. ion by any person following the information offered or provided within this support form. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 21, 2004 Report Share Posted December 21, 2004 I saw this on the news this morning and I was on Naproxen for about a year. Oh this is scary. I took Vioxx and it made me sick and stopped then the same with celebrex. How they don't do studies on these I will never understand. I even took alive and it made me very sick too so I stopped that too. Hugs; GingerMarilyn Hogg wrote: U.S. government halts naproxen Alzheimer trials Associated Press WASHINGTON — A U.S. government study testing whether Celebrex or naproxen would reduce the risk of Alzheimer's disease was halted Monday after researchers noted an increase in heart attack and stroke among participants who were taking naproxen, an over-the-counter pain reliever on the market for nearly 30 years. Officials at the National Institutes of Health said the study was stopped after three years when it was noticed patients taking naproxen, sold under the brand name Aleve, had a 50-per-cent greater incidence of cardiovascular events -- heart attack or stroke -- than patients taking placebo. Another factor, officials said, was the announcement last week that advertising for Celebrex was being halted after a study found high doses of the drug were associated with an increase in heart attack risk. Data from the Alzheimer's study, however, did not indicate an increased risk for heart attack or stroke. Celebrex and naproxen are both pain relievers commonly used to treat arthritis. Naproxen has been approved for sale in the United States, first as a prescription and then as an over-the-counter drug, since 1976. Efforts to obtain reaction Monday night produced no answers at phone numbers for Bayer Healthcare, the maker of Aleve, a popular version of naproxen. Dr. Kweder of the U.S. Food and Drug Administration said the NIH study is the first to show naproxen might increase the risk of heart attack or stroke. "We agree that this is confusing,'' she said. The FDA will closely evaluate the findings from the NIH study, said Kweder, but that no new regulatory action with naproxen is expected within the next few days. She said patients who routinely take naproxen should follow the drug directions carefully, including the instruction not to take it for more than 10 days and to consult a doctor if there continues to be pain. The Alzheimer's disease study was being conducted by the National Institute on Aging, an arm of the NIH. It called for 2,500 patients, aged 70 or older and who had a family history of Alzheimer's, to take either Celebrex, naproxen or placebo. The group was divided and each division, or arm, was assigned to receive one of the drugs or placebo. The drugs were blinded, which means the patients did not know which medication they were taking. The goal was to determine if the pain-relieving drugs lowered the risk of developing Alzheimer's disease. The study started three years ago and was to continue for a few more years. Officials said the patients in the study will be monitored for developing Alzheimer's but will not be given the test drugs. Dr. Elias Zerhouni, director of the National Institutes of Health, said the study linking heart attack to Celebrex last week was a major factor in deciding to suspend the Alzheimer's study. He said there was a question whether patients in the study would continue to take their medicine since they knew they might be taking Celebrex. Suspending the study, Zerhouni said, "is the prudent thing to do.'' Breitner of the Veterans Affairs medical facility in Seattle and the University of Washington, an investigator in the trial, said only preliminary data is available. But it suggests about 70 patients of the 2,500 suffered stroke or heart attack, including 23 deaths and there were about 50 per cent more such events in the naproxen arm of the study than in the placebo division. Visit the Still's Disease Message Boardhttp://disc.server.com/Indices/148599.htmlThe materials and information contained in this message are not intended to replace the services of a trained health professional or to be a substitute for medical advice of physicians and/or other health care professionals. The International Still's Disease Foundation is not engaged in rendering medical or professional medical services. You should consult your physician on specific medical questions, particularly in matters requiring diagnosis or medical attention. The International Still's Disease Foundation makes no representations or warranties with respect to any treatment, action, application, medication or preparation by any person following the information offered or provided within this support form. ion by any person following the information offered or provided within this support form. But God demonstrates His own love toward us, in that while we were yet sinners, Christ died for us. .. ette Follow Jesus! <))>< Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 23, 2004 Report Share Posted December 23, 2004 I just wanted to add my two cents in.. On al the drugs being recalled. When the first started to medicate me they had tried Vioxx but it didn't work for me, same with Celebrex. The one the did put me on is Voltaren, 75mgs twice a day. I have to say that seems to be helping a lot. I stopped taking it and felt the pain more. I since have started back on it per my Rhuemy and I have to say I feel somewhat better. With being on this and the MTX I cant take advil or aleve. Just thought I would let you know there is something else out there that helps someone. Love Kelley in Colorado -- Re: Naproxen Warning Hi Marilyn, I saw that on the news last night and I couldn't believe it! The Naproxen (Aleve) was what I had switched to from Celebrex. Now what? My husband says I should try herbal, but I just don't know. I don't think he really understands the pain. What does everyone else think? Post your free ad now! Yahoo! Canada Personals Visit the Still's Disease Message Board http://disc.server.com/Indices/148599.html The materials and information contained in this message are not intended to replace the services of a trained health professional or to be a substitute for medical advice of physicians and/or other health care professionals. The International Still's Disease Foundation is not engaged in rendering medical or professional medical services. You should consult your physician on specific medical questions, particularly in matters requiring diagnosis or medical attention. The International Still's Disease Foundation makes no representations or warranties with respect to any treatment, action, application, medication or preparation by any person following the information offered or provided within this support form. ion by any person following the information offered or provided within this support form. Quote Link to comment Share on other sites More sharing options...
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