[PROVE] Damage from toxins can pass to offspring

[Guest guest]

[PROVE Note: Veterinarians for years have been talking about the horrible

effects from multiple generations of vaccinations on animals. Now research

shows that genetic damage from toxins you have been exposed to can indeed be

passed down. It makes you wonder with all the toxic ingredients in vaccines what

we are doing to our children, grandchildren, ...etc.]

Damage from toxins can pass to offspring

By Weise, USA TODAY

6/2/2005

http://www.usatoday.com/news/health/2005-06-02-toxin-offspring_x.htm

Scientists have shown for the first time that exposure to environmental toxins

can cause permanent genetic changes that are passed down through generations.

The research on rats by a team of scientists led by Skinner at

Washington State University in Pullman, Wash., may hold the key to the mystery

of male infertility, which some researchers say has been increasing for unknown

reasons for 20 years.

According to a report in today's edition of the journal Science, Skinner's team

was working with two commonly used chemicals, an insecticide called methoxychlor

and a fungicide called vinclozolin. Both are known to cause infertility in the

male offspring of pregnant animals.

The scientists were looking at the rats and their offspring. But when the

offspring had offspring, the researchers were shocked by what they found in this

second generation. And they were even more surprised by subsequent generations

of the lab rats.

" Lo and behold they had the same " infertility problems, says Skinner, director

of the university's Center for Reproductive Biology.

Not only the grandsons but also the great-grandsons and great-great grandsons of

the exposed mother were similarly affected. The scientists had discovered a

mechanism that permanently changed the reproductive cells.

" That (the changes are) carried down through the generations is what's new and

novel here, " says Turek, a male infertility specialist at the University of

California at San Francisco. " Everyone agrees that exposure of the fetus at a

certain critical time can cause malformed organs and birth defects. But no one

ever imagined this might persist at some level for three more generations. "

Skinner notes that rat studies cannot necessarily be applied to humans, but he

said the findings warrant a close look at the potential health hazards of

environmental chemicals.

The exposure appears to produce what's called an epigenetic effect, in which a

chemical modification of the DNA in the animal's reproductive cells causes an

alteration with potentially disastrous results — in this case, infertility.

Epigenetic effects are generally erased with each new generation when the cells

that form the sperm or eggs are created in the embryo. But in this case, the

affected genes maintained the alteration and escaped the reprogramming process.

Skinner cautions that the doses used in his research are higher than those

normally found in the environment. He plans to begin testing at lower doses to

see whether the same changes appear.

Human exposure to methoxychlor, which is being phased out in the USA, and

vinclozolin is mostly restricted to agricultural workers, though there's not

much data to go on, Skinner says. He expects that other researchers will now

begin looking for similar effects in people.

But " to the extent that it's been studied, the epigenetic effects seen in

rodents are similar to those seen in humans, " says McCarrey, an expert on

epigenetics at the University of Texas at San .

The findings may one day facilitate new diagnostic approaches and therapies,

Skinner says. For example, doctors would be on the lookout much earlier for

certain diseases if they knew that their patients' ancestors had been exposed to

certain toxins, he says.

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Dawn

PROVE(Parents Requesting Open Vaccine Education)

prove@... (email)

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