Re: Treatment interruption results in lipid reduction; IL-2 has no effect on lipids

[Guest guest]

Would a cd4 count of 109 at diagnosis be too low to consider a treatment

interruption?

Viral load was @100,000. Thanks guys.

[Guest guest]

I'm sorry. That was my cd4 count and viral load 6 years ago when I was

diagnosed. I've

been undetectable ever since then and my cd4 count is in the 600-700s. I was

just

wondering about a treatment interruption based off the new info posted here.

[Guest guest]

,

Nobody can predict what will happen to you. When

treatment interruptions have been studied, there is a

general pattern of CD4 and viral load returning to

baseline, often quite quickly. This suggests that most

likely your counts would trend toward your

pre-treatment levels. This would tend to argue againts

a treatment interruption in your case.

However, it isn't entirely predictable. What happens

most often in a large group of people isn't guarenteed

to happen to you. For example, my pre-treament CD4

count was 24 and my viral load 250,000- a bad

candidate for treatment interruption. After much back

and forth with my doc, she and I agreed to try one,

but to be careful with it. We set firm paramaters for

restarting treatment- viral load going over 75K, CD

count dipping below 350. I expected to get maybe a few

months off treament at best. I was off meds for almost

3 years before my CD4 count went low enough for me to

restart.

So, I would suggest you do a cost/benefit analysis for

yourself. What are your reasons for wanting an

interruption? Can you and your doc monitor your

numbers extra closely for a while after you stop meds?

Did you have any OIs prior to starting on meds? How

high is your CD4 count now? These are just some of the

questions to go over with your doc, to make a good

decision.

I think the bottom line here is that many wouldn't

consider you a good candidate for a treatment

interruption- based on the research. However you could

make an entirely reasonable decision to take break.

paul

--- wetcity68 wrote:

>

> Would a cd4 count of 109 at diagnosis be too low to

> consider a treatment interruption?

> Viral load was @100,000. Thanks guys.

>

>

>

>

>

>

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[Guest guest]

I was at the Lipodystrophy Workshop & heard the presentation & spoke with conference attendees. The use of IL-2 in a situation like this in real life is questionable. In general interruptions can be risky.

Jules Levin

I'm sorry. That was my cd4 count and viral load 6 years ago when I was diagnosed. I've

been undetectable ever since then and my cd4 count is in the 600-700s. I was just

wondering about a treatment interruption based off the new info posted here.