Guest guest Posted December 6, 2011 Report Share Posted December 6, 2011 But all anti-androgens are far from a panacea. One should realize that the bulk of these preparations used in transgender medicine are comprised of drugs that produce an anti-androgenic effect incidental to their designed purpose. The anti-androgens that some transgender patients are taking, are being taken by many others for a variety of very different medical conditions that include anti-hypertensive treatment (reducing high blood pressure), treating prostactic cancer, prostatic enlargement, and fungal conditions, amongst others. And as common sense would dictate, these drugs with their wide scope of uses may also produce a wide variety of potentially serious side effects. For example, a particular drug when used in treating cancer may work within acceptable limits of overall risk, even though it produces a certain stain on the liver. But when the same drug is used to add a mild anti-androgenic (de-masculinizing) effect to an otherwise healthy individual, are the mild feminizing effects of this mediation worth the potentially serious health risks associated with its use? This is the question the transgender patient should consider, and naturally, the physician entrusted with the care of that individual is also considering. Looks like at the minimum we should decide if we want to go the transgender route. I know at one point it was asked if spironolactone was used for sex changes and the answer was " Not that I am aware of " if memory serves me right. I can now say it is the medicine of choice dosed at 100 to 200 mg along with a supplemental estrogen medicine according to atleast one support site! ..... Quote Link to comment Share on other sites More sharing options...
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