Breast lumps/spiro

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I have two thoughts on discussion: 1.) Having had breast cancer, I'd get a mammogram & probably biopsy ASAP. I had three spots of cancer in one breast, two intra-ductal and one 1.7 mm invasive which did not show on the mammogram. On the other breast, nothing showed but they found a 1.3 cm intra-ductal lesion. Intra-ductal (DCIS) is thought to have not spread. In fact, only slightly more than 50% of DCIS spread but since they don't know which DCIS is going to spread, aggressive treatment is necessary. 2.) Quite honestly, if I was in your predicament, I'd get AVS (at a competent center) and go for surgery if one side could be localized. Let them see if AVS and surgery are cheaper than Inspra. 3.) About not being able to get proper treatment through the government program you're in, it figures, and it boggles my mind to think people want government doling that mediocrity out to everyone. Whatever happened to doctors treating patients? Val From: hyperaldosteronism [mailto:hyperaldosteronism ] On Behalf Of Val, you raise a couple very good points. I want to mention that it took me 10 months to get ALL SX of Conn's under control after BP resolution, this documented by resolution of frequent urinating and pain. We have attributed that to 10 months to get NA under control but I personally am not sure our body is all that simple! I agree that it appears something else is involved and as you uncover and resolve one issue often it allows something else to raise its ugly head.It's hard for me to talk in abstract so let me switch to my case. I feel quite strongly that while Spironlactone (25mg bid) has done wonders for my Conn's it has raised havoc with other systems. I've spoken recently about hormonal issues as I research Gynecomastia and breast masses. What I haven't spent a lot of time on is the lack of libido or the physical changes, it appears the increase in size upstairs is directly proportional to the reduction in size downstairs! (This is only a problem when I go to pee since libido is zero!) As I wrote this I decided to review potential side effects at:http://www.drugs.com/sfx/spironolactone-side-effects.htmlAs I reviewed that I immediately realized there were other symptoms: Digestive, Endocrine and probably Nervous System/Psychiatric. I realize Dr. Grim will say I should have been switched to Eplerenone and I will agree and point out I attempted over a year ago when Gynecomasteia started to appear. Unfortunately politics, ins. regs., doctor apprehension and costs prevented that. (Now that I have scared the doctor with breast nodules she is on board! Maybe I get to learn how to treat cancer now that HTN is under control!) The switch has been actively pursued for over 2 weeks, refused once and we are at the VA Director's level now - he's zero for one with one outstanding so far! BTW Dr. Grim, I also found this stmt. At drugs.com: OncologicOncologic side effects have included isolated case reports of tumorigenesis but this has not been substantiated in large studies.Animal studies have suggested an association between spironolactone with benign adenomas of the thyroid and testes, malignant breast tumors, proliferative changes in the liver, including hepatocellular carcinoma, and leukemia. Dosages used in these studies were 25 to 250 times the maximum recommended human dosage (on a per kg basis).There is certainly plenty of room to discount it. It is hard or impossible to do a large study if the chances of a positive is only one or two in a million, besides why bother with those large odds (unless you are one of those one or two!) I'm also sure I will hear that those are extremely high doses, what if you are extremely sensitive?As for ita, I don't know how long ago she made the switch but it does appear she is on a huge dose of the meds, IMHO! What effect does the hormonal changes do to the female body system? When she switched and suddenly released the flow of testosterone what does it do? Is she experiencing Male Pattern Baldness? I'm not really qualified to even guess so I won't offer any more but I have never heard (or at least remember hearing) the proper way to switch meds, especially when on such large doses.In the interest of keeping this short (that's rhetoric if you missed it) I will close for now. I do hope I have piqued interest and this will generate some discussion. - 65 yo super ob. male - 12mm X 13mm rt. a.adnoma with previous rt. flank pain. Treating with Meds. And DASH. . Current BP(last week ave): 131/76 HR 60Other Issues/Opportunities: OSA w Bi-Pap settings 13/19, DM2, and PTSD.Meds: Duloxetine hcl 80 MG, Metoprolol Tartrate 200 MG, 81mg asprin, Metformin 2000MG and Spironolactone 50 MG. _._,_.___Reply to sender | Reply to group | Reply via web post | Start a New Topic Messages in this topic (64) Recent Activity: · New Members 1 · New Links 2 Visit Your Group MARKETPLACEStay on top of your group activity without leaving the page you're on - Get the Yahoo! Toolbar now.Switch to: Text-Only, Daily Digest • Unsubscribe • Terms of Use.