New studies on prevalence of thyroid problems in PA and HTN. At least if you are Italian.

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Am J Hypertens. 2011 Aug 18. doi: 10.1038/ajh.2011.144. [Epub ahead of print]Blood Pressure, Thyroid-Stimulating Hormone, and Thyroid Disease Prevalence in Primary Aldosteronism and Essential Hypertension.Turchi F, Ronconi V, di Tizio V, Boscaro M, Giacchetti G.SourceDepartment of Internal Medicine, Division of Endocrinology, Università Politecnica delle Marche, Ospedali Riuniti "Umberto I-G.M. Lancisi-G. Salesi", Ancona, Italy.AbstractBackgroundA positive correlation between thyroid-stimulating hormone (TSH) and blood pressure (BP) has been identified in normotensives and in patients with essential hypertension (EH). This study was designed to evaluate, in primary aldosteronism(PA) and in EH, potential association of BP, TSH, and ultrasonographic changes of the thyroid.MethodsWe studied 188 patients: 92 with PA and 96 matched essential hypertensives. Clinical and ambulatory BP (ABP), and thyroid function were evaluated in all patients. In PA and in a subgroup of EH patients (n = 65) thyroid ultrasonography was performed.ResultsIn PA patients, diastolic office and diastolic ABP increased across TSH quartiles and multivariate analysis confirmed a positive significant correlation between TSH and diastolic BP, independently of aldosterone levels, body mass index (BMI), duration of hypertension, and age. In EH patients, we found a significant linear increase in systolic and diastolic ABP with increasing TSH. The prevalence of thyroid dysfunctions was similar in PA and EH (15% and 19%, respectively). In PA patients, we found a higher prevalence of ultrasonographic alterations than in EH (66% vs. 46%, P < 0.05). PA patients presenting morphological abnormalities had higher homeostasis model assessment-insulin resistance levels than patients with normal gland at ultrasonography (4.2 ± 1.8 vs. 3.1 ± 0.8 P < 0.05).ConclusionsWe found a positive correlation between TSH and BP both in PA and EH patients. Moreover, in PA patients we observed a high prevalence of thyroid morphological alterations.American Journal of Hypertension (2011). doi:10.1038/ajh.2011.144.

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I had hyperthyroid with PA. I suspect I have had it a few times come and go - I knew about a 0.01 TSH in 2008 while in the hospital and then late 2009/2010 I had it again. Each time after a bad bout of confirmed flu. Since Summer of 2010 no return that I can feel. But I had a mother who had it, and 2 sisters who do. No history of hypo, only hyper with all of us. I guess they had to shut one sisters down. I just learned about this with my sisters. As far as I know and checked I am the one who has HTN and low K. But I told them to watch their BP's closely. My dad is 62 and he doesn't have HTN. I thought he did, but nope. 2 brothers and one has Paget's disease, but no HTN or thyroid issues (were all full blood related). Grandpa died of a massive stroke, as did all of my great uncles and greatgrandfather, and all had HTN, but no record of

low K.

I will say this....hyperthyroidism could ONLY be invented by the devil. I would not wish it on any of my enemies (Ok, maybe those who blew it off or treated me like crap). It is really a living hell. Now, I had the low K issue, which I now credit to alot of my issues at the same time, but the heart pouding through the chest feels like a sledgehammer from the inside and NEVER stops, the feeling hot all the time, the eyes, the headaches, and on and on....it was like living in hell.....well I never lived with my mother-in-law..... but I can only imagine.............

Subject: New studies on prevalence of thyroid problems in PA and HTN. At least if you are Italian.To: hyperaldosteronism Date: Saturday, October 29, 2011, 2:34 AM

Am J Hypertens. 2011 Aug 18. doi: 10.1038/ajh.2011.144. [Epub ahead of print]

Blood Pressure, Thyroid-Stimulating Hormone, and Thyroid Disease Prevalence in Primary Aldosteronism and Essential Hypertension.

Turchi F, Ronconi V, di Tizio V, Boscaro M, Giacchetti G.

Source

Department of Internal Medicine, Division of Endocrinology, Università Politecnica delle Marche, Ospedali Riuniti "Umberto I-G.M. Lancisi-G. Salesi", Ancona, Italy.

Abstract

BackgroundA positive correlation between thyroid-stimulating hormone (TSH) and blood pressure (BP) has been identified in normotensives and in patients with essential hypertension (EH). This study was designed to evaluate, in primary aldosteronism(PA) and in EH, potential association of BP, TSH, and ultrasonographic changes of the thyroid.MethodsWe studied 188 patients: 92 with PA and 96 matched essential hypertensives. Clinical and ambulatory BP (ABP), and thyroid function were evaluated in all patients. In PA and in a subgroup of EH patients (n = 65) thyroid ultrasonography was performed.ResultsIn PA patients, diastolic office and diastolic ABP increased across TSH quartiles and multivariate analysis confirmed a positive significant correlation between TSH and diastolic BP, independently of aldosterone levels, body mass index (BMI), duration of hypertension, and age. In EH patients, we found a significant linear increase in systolic

and diastolic ABP with increasing TSH. The prevalence of thyroid dysfunctions was similar in PA and EH (15% and 19%, respectively). In PA patients, we found a higher prevalence of ultrasonographic alterations than in EH (66% vs. 46%, P < 0.05). PA patients presenting morphological abnormalities had higher homeostasis model assessment-insulin resistance levels than patients with normal gland at ultrasonography (4.2 ± 1.8 vs. 3.1 ± 0.8 P < 0.05).ConclusionsWe found a positive correlation between TSH and BP both in PA and EH patients. Moreover, in PA patients we observed a high prevalence of thyroid morphological alterations.American Journal of Hypertension (2011). doi:10.1038/ajh.2011.144.