Re: Links between Spironolactone and gastric problems

[Guest guest]

Thanks for this article. Is this another good reason for an andrelectomy over

long term medicines? Is this part of the med. control the same in Elperenone so

the effect would be the same?

- 65 yo super ob. male - 12mm X 13mm rt. a.adnoma with previous rt. flank

pain. Treating with Meds. And DASH. . Current BP(last week ave): 131/76 HR 60

Other Issues/Opportunities: OSA w Bi-Pap settings 13/19, DM2, and PTSD.

Meds: Duloxetine hcl 80 MG, Metoprolol Tartrate 200 MG, 81mg asprin, Metformin

2000MG and Spironolactone 50 MG.

>

> I have had an endoscopy today which indicates some erosion of the first part

of the duodenun, gastritis and a small hiatus hernia.

>

> I have done some research on possible links to taking spiro (now 150mg

daily)which I have done since diagnosed with conn's in 2004. My conn's is stable

and I am currently discharged from King's College Hospital (London) endo dept.

BP is fine (115/78 today at hospital). The stomach stuff has been going on since

January.

>

> Found this online:

> http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1539051/?tool=pmcentrez - main

point:

>

> Conclusion The risk of gastroduodenal ulcers or upper gastrointestinal

bleeding is significantly increased in patients using spironolactone.

>

>

> Has anyone else experienced stomach problems from taking spiro long term?

>

[Guest guest]

Much more likely related to K tablets or caps ICU are taking the May your pressure be low!CE Grim MS, MDSpecializing in DifficultHypertension

I have had an endoscopy today which indicates some erosion of the first part of the duodenun, gastritis and a small hiatus hernia.

I have done some research on possible links to taking spiro (now 150mg daily)which I have done since diagnosed with conn's in 2004. My conn's is stable and I am currently discharged from King's College Hospital (London) endo dept. BP is fine (115/78 today at hospital). The stomach stuff has been going on since January.

Found this online:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1539051/?tool=pmcentrez - main point:

Conclusion The risk of gastroduodenal ulcers or upper gastrointestinal bleeding is significantly increased in patients using spironolactone.

Has anyone else experienced stomach problems from taking spiro long term?

[Guest guest]

Thanks for the comment, be reassured my world is perfectly in perspective... I

just wanted to see if this is something anyone else has had happen that has been

linked to Spiro use.

> >

> > I have had an endoscopy today which indicates some erosion of the first part

of the duodenun, gastritis and a small hiatus hernia.

> >

> > I have done some research on possible links to taking spiro (now 150mg

daily)which I have done since diagnosed with conn's in 2004. My conn's is stable

and I am currently discharged from King's College Hospital (London) endo dept.

BP is fine (115/78 today at hospital). The stomach stuff has been going on since

January.

> >

> > Found this online:

> > http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1539051/?tool=pmcentrez - main

point:

> >

> > Conclusion The risk of gastroduodenal ulcers or upper gastrointestinal

bleeding is significantly increased in patients using spironolactone.

> >

> >

> > Has anyone else experienced stomach problems from taking spiro long term?

> >

>

>

>

>

> ------------------------------------

>

>

[Guest guest]

No idea what ASA is!!! I don't take anything except spiro.

> > >

> > > I have had an endoscopy today which indicates some erosion of the

> > first part of the duodenun, gastritis and a small hiatus hernia.

> > >

> > > I have done some research on possible links to taking spiro (now

> > 150mg daily)which I have done since diagnosed with conn's in 2004.

> > My conn's is stable and I am currently discharged from King's

> > College Hospital (London) endo dept. BP is fine (115/78 today at

> > hospital). The stomach stuff has been going on since January.

> > >

> > > Found this online:

> > > http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1539051/?

> > tool=pmcentrez - main point:

> > >

> > > Conclusion The risk of gastroduodenal ulcers or upper

> > gastrointestinal bleeding is significantly increased in patients

> > using spironolactone.

> > >

> > >

> > > Has anyone else experienced stomach problems from taking spiro

> > long term?

> > >

> >

> >

> >

> >

> > ------------------------------------

> >

> >

[Guest guest]

Aspirin (Acetylsalicylic Acid; ASA)

> > > >

> > > > I have had an endoscopy today which indicates some erosion of the

> > > first part of the duodenun, gastritis and a small hiatus hernia.

> > > >

> > > > I have done some research on possible links to taking spiro (now

> > > 150mg daily)which I have done since diagnosed with conn's in 2004.

> > > My conn's is stable and I am currently discharged from King's

> > > College Hospital (London) endo dept. BP is fine (115/78 today at

> > > hospital). The stomach stuff has been going on since January.

> > > >

> > > > Found this online:

> > > > http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1539051/?

> > > tool=pmcentrez - main point:

> > > >

> > > > Conclusion The risk of gastroduodenal ulcers or upper

> > > gastrointestinal bleeding is significantly increased in patients

> > > using spironolactone.

> > > >

> > > >

> > > > Has anyone else experienced stomach problems from taking spiro

> > > long term?

> > > >

> > >

> > >

> > >

> > >

> > > ------------------------------------

> > >

> > >

[Guest guest]

Font Size

A

A

ASA (drug caution code): Abbreviation on a medication that indicates it contains

acetylsalicylic acid (aspirin).

- 65 yo super ob. male - 12mm X 13mm rt. a.adnoma with previous rt. flank

pain. Treating with Meds. And DASH. . Current BP(last week ave): 131/76 HR 60

Other Issues/Opportunities: OSA w Bi-Pap settings 13/19, DM2, and PTSD.

Meds: Duloxetine hcl 80 MG, Metoprolol Tartrate 200 MG, 81mg asprin, Metformin

2000MG and Spironolactone 50 MG.

> > > >

> > > > I have had an endoscopy today which indicates some erosion of the

> > > first part of the duodenun, gastritis and a small hiatus hernia.

> > > >

> > > > I have done some research on possible links to taking spiro (now

> > > 150mg daily)which I have done since diagnosed with conn's in 2004.

> > > My conn's is stable and I am currently discharged from King's

> > > College Hospital (London) endo dept. BP is fine (115/78 today at

> > > hospital). The stomach stuff has been going on since January.

> > > >

> > > > Found this online:

> > > > http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1539051/?

> > > tool=pmcentrez - main point:

> > > >

> > > > Conclusion The risk of gastroduodenal ulcers or upper

> > > gastrointestinal bleeding is significantly increased in patients

> > > using spironolactone.

> > > >

> > > >

> > > > Has anyone else experienced stomach problems from taking spiro

> > > long term?

> > > >

> > >

> > >

> > >

> > >

> > > ------------------------------------

> > >

> > >

[Guest guest]

Interestingly the NHS drug info pages give gastrointestinal problems as a

possible side effect of aking Spiro long term.

http://www.nhs.uk/medicine-guides/pages/MedicineSideEffects.aspx?condition=Blood\

%20pressure & medicine=spironolactone & preparation=Spironolactone%20100mg%20tablets

I also now have a very irregular if at all menstrual cycle for the past 2 years

although hormones fine after blood tests.

Which makes me wonder re a possible common causal factor. 7 years of taking a

drug is a long time.

> > >

> > > I have had an endoscopy today which indicates some erosion of the first

part of the duodenun, gastritis and a small hiatus hernia.

> > >

> > > I have done some research on possible links to taking spiro (now 150mg

daily)which I have done since diagnosed with conn's in 2004. My conn's is stable

and I am currently discharged from King's College Hospital (London) endo dept.

BP is fine (115/78 today at hospital). The stomach stuff has been going on since

January.

> > >

> > > Found this online:

> > > http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1539051/?tool=pmcentrez - main

point:

> > >

> > > Conclusion The risk of gastroduodenal ulcers or upper gastrointestinal

bleeding is significantly increased in patients using spironolactone.

> > >

> > >

> > > Has anyone else experienced stomach problems from taking spiro long term?

> > >

> >

> >

> >

> >

> > ------------------------------------

> >

> >

[Guest guest]

Thanks. Will talk to my GP.

> > > > >

> > > > > I have had an endoscopy today which indicates some erosion of the

first part of the duodenun, gastritis and a small hiatus hernia.

> > > > >

> > > > > I have done some research on possible links to taking spiro (now 150mg

daily)which I have done since diagnosed with conn's in 2004. My conn's is stable

and I am currently discharged from King's College Hospital (London) endo dept.

BP is fine (115/78 today at hospital). The stomach stuff has been going on since

January.

> > > > >

> > > > > Found this online:

> > > > > http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1539051/?tool=pmcentrez -

main point:

> > > > >

> > > > > Conclusion The risk of gastroduodenal ulcers or upper gastrointestinal

bleeding is significantly increased in patients using spironolactone.

> > > > >

> > > > >

> > > > > Has anyone else experienced stomach problems from taking spiro long

term?

> > > > >

> > > >

> > > >

> > > >

> > > >

> > > > ------------------------------------

> > > >

> > > >