Super high estrogen

[Guest guest]

I am working with 2 ladies who are in their early 40's.  They appear to have some ovulatory and some non-ovulatory cycles.  I figure this is typical at this time of life.In the last apparently non-ovulatory cycle of one woman her peak + 7 estradiol level was over 700!  We had started some progesterone on her just prior to that and her progesterone level was a mere 7.  I doubled her progesterone at that point to finish out the cycle and hopefully balance some of the estrogen effect.  The estrogen swings seem to give her horrible migraines and crippling mood symptoms.  Any suggestions on what to do?  She is not seeking pregnancy, but I have thought about trying metformin (since she does have some acne) or clomid to induce (hopefully healthy) ovulations.

Amy Hogan, MD

[Guest guest]

But what to do with the estrogen load..... just progesterone- as high as I can get it?

 

AH

 

Really not medically justified in using clomid  if pt is not interested in fertility; Just cycle with progesterone post peakSent from my iPhone

 

I am working with 2 ladies who are in their early 40's.  They appear to have some ovulatory and some non-ovulatory cycles.  I figure this is typical at this time of life.In the last apparently non-ovulatory cycle of one woman her peak + 7 estradiol level was over 700!  We had started some progesterone on her just prior to that and her progesterone level was a mere 7.  I doubled her progesterone at that point to finish out the cycle and hopefully balance some of the estrogen effect.  The estrogen swings seem to give her horrible migraines and crippling mood symptoms.  Any suggestions on what to do?  She is not seeking pregnancy, but I have thought about trying metformin (since she does have some acne) or clomid to induce (hopefully healthy) ovulations.

Amy Hogan, MD

[Guest guest]

Have you checked whether there may be an estrogen secreting

tumor of the ovary, such as a granulosa cell tumor or thecoma?

Hanna Klaus

From:

nfpprofessionals [mailto:nfpprofessionals ] On

Behalf Of Amy Hogan

Sent: Wednesday, December 30, 2009 11:05 AM

To: nfpprofessionals

Subject: Re: Super high estrogen

But what to do with the estrogen load..... just

progesterone- as high as I can get it?

AH

On Wed, Dec 30, 2009 at 7:30 AM, lruppersberger

wrote:

Really not medically justified in

using clomid if pt is not interested in fertility;

Just cycle with progesterone post peak

Sent from my iPhone

I am working with 2 ladies who are in their early

40's. They appear to have some ovulatory and some non-ovulatory

cycles. I figure this is typical at this time of life.

In the last apparently non-ovulatory cycle of one woman her peak + 7 estradiol

level was over 700! We had started some progesterone on her just prior to

that and her progesterone level was a mere 7. I doubled her progesterone

at that point to finish out the cycle and hopefully balance some of the

estrogen effect. The estrogen swings seem to give her horrible migraines

and crippling mood symptoms. Any suggestions on what to do? She is

not seeking pregnancy, but I have thought about trying metformin (since she

does have some acne) or clomid to induce (hopefully healthy) ovulations.

Amy Hogan, MD