Guest guest Posted December 1, 2011 Report Share Posted December 1, 2011 If you are referencing gyno, there is a lot of similarities if you do a pubmed search and specifically " Male Breast Cancer " ! And BTW, Spironlactone can have a major impact on that 3rd leg, IMHE! Have you ever personally experienced the long term effects of a low dose regiment of the drug? - 65 yo super ob. male - 12mm X 13mm rt. a.adnoma with previous rt. flank pain. Treating with Meds. And DASH. . Current BP(last week ave): 131/76 HR 60 Other Issues/Opportunities: OSA w Bi-Pap settings 13/19, DM2, and PTSD. Meds: Duloxetine hcl 80 MG, Metoprolol Tartrate 200 MG, 81mg asprin, Metformin 2000MG and Spironolactone 50 MG. > > > > > > > > > > > > > > > > > Dr. Grim > > > > > > > > > > > > > > > > > > Do you have any experience treating PTNs w/spironlactone > > > > who develop gynocomastia and breast tumors? I am specifically > > > > interested in the effect on Estrogen and Testosterone in males and > > > > preparing for a CTJ (Come To Jesus) meeting with the VA in the > > > > morning. > > > > > > > > > > > > > > > > > > - 65 yo super ob. male - 12mm X 13mm rt. a.adnoma > > > > with previous rt. flank pain. Treating with Meds. And DASH. . > > > > Current BP(last week ave): 131/76 HR 60 > > > > > > > > > Other Issues/Opportunities: OSA w Bi-Pap settings 13/19, > > > > DM2, and PTSD. > > > > > > > > > Meds: Duloxetine hcl 80 MG, Metoprolol Tartrate 200 MG, > > > > 81mg asprin, Metformin 2000MG and Spironolactone 50 MG. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 1, 2011 Report Share Posted December 1, 2011 Most likely same receptor that you have on breast tissue that is affecting the other areas. Likely some have it and some don't. CE Grim MD If you are referencing gyno, there is a lot of similarities if you do a pubmed search and specifically "Male Breast Cancer"! And BTW, Spironlactone can have a major impact on that 3rd leg, IMHE! Have you ever personally experienced the long term effects of a low dose regiment of the drug? - 65 yo super ob. male - 12mm X 13mm rt. a.adnoma with previous rt. flank pain. Treating with Meds. And DASH. . Current BP(last week ave): 131/76 HR 60 Other Issues/Opportunities: OSA w Bi-Pap settings 13/19, DM2, and PTSD. Meds: Duloxetine hcl 80 MG, Metoprolol Tartrate 200 MG, 81mg asprin, Metformin 2000MG and Spironolactone 50 MG. > > > > > > > > > > > > > > > > > Dr. Grim > > > > > > > > > > > > > > > > > > Do you have any experience treating PTNs w/spironlactone > > > > who develop gynocomastia and breast tumors? I am specifically > > > > interested in the effect on Estrogen and Testosterone in males and > > > > preparing for a CTJ (Come To Jesus) meeting with the VA in the > > > > morning. > > > > > > > > > > > > > > > > > > - 65 yo super ob. male - 12mm X 13mm rt. a.adnoma > > > > with previous rt. flank pain. Treating with Meds. And DASH. . > > > > Current BP(last week ave): 131/76 HR 60 > > > > > > > > > Other Issues/Opportunities: OSA w Bi-Pap settings 13/19, > > > > DM2, and PTSD. > > > > > > > > > Meds: Duloxetine hcl 80 MG, Metoprolol Tartrate 200 MG, > > > > 81mg asprin, Metformin 2000MG and Spironolactone 50 MG. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 2, 2011 Report Share Posted December 2, 2011 Do you have any more info what that " receptor " may be or where I might look to find more about it? I'm thinking of following up some more and see if I can identify a condition where Spironlactone might not be the idea solution. (May also identify good canidates for M2F transgender therapy!) I checked with Chaz , but he went the wrong way-he my be a resource if I decide to undo everything! ;>) I'm doing some of this follow on because I fully intend to make some changes that affected my treatment. (Atleast people will know how I feel!) I really think spironlactone is the wrong first line drug to treat PA. I know there were a few fathers that would have liked to reduce my testosterone back in the 60's but that has been less of a problem since I turned 60! I'm unsure how the women feel about it and if they appreciate the extra available estrogen but opinions are welcome! (I thought of testing my theory on my wife but I'd be in deep shit if my theory is correct!) I'm also following the direction of my PCP to the letter regarding the treatment of the gynocomastia since that is part of the overall cost of treatment. I have already contacted Sen. Bernie ' office regarding the sexual descrimination issue. (Female vets are guaranteed a Mammogram in <50 miles and I have to travel over 400 miles and probably loose 2 days!) If he can't resolve this issue, I bet I can find someone to file class action suit! - 65 yo super ob. male - 12mm X 13mm rt. a.adnoma with previous rt. flank pain. Treating with Meds. And DASH. . Current BP(last week ave): 131/76 HR 60 Other Issues/Opportunities: OSA w Bi-Pap settings 13/19, DM2, and PTSD. Meds: Duloxetine hcl 80 MG, Metoprolol Tartrate 200 MG, 81mg asprin, Metformin 2000MG and Spironolactone 50 MG. > > > > > > > > > > > > > > > > > > > > > Dr. Grim > > > > > > > > > > > > > > > > > > > > > > Do you have any experience treating PTNs w/ > > spironlactone > > > > > > who develop gynocomastia and breast tumors? I am specifically > > > > > > interested in the effect on Estrogen and Testosterone in > > males and > > > > > > preparing for a CTJ (Come To Jesus) meeting with the VA in the > > > > > > morning. > > > > > > > > > > > > > > > > > > > > > > - 65 yo super ob. male - 12mm X 13mm rt. > > a.adnoma > > > > > > with previous rt. flank pain. Treating with Meds. And DASH. . > > > > > > Current BP(last week ave): 131/76 HR 60 > > > > > > > > > > > Other Issues/Opportunities: OSA w Bi-Pap settings > > 13/19, > > > > > > DM2, and PTSD. > > > > > > > > > > > Meds: Duloxetine hcl 80 MG, Metoprolol Tartrate > > 200 MG, > > > > > > 81mg asprin, Metformin 2000MG and Spironolactone 50 MG. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 2, 2011 Report Share Posted December 2, 2011 Do a pubmed on mechanisms of gynecomastia with spiro if you have not. That may give some info. There has been no study to test the benefit of doing mammograms routinely in men. But with gyneco it should not be a problem to get OKed but I would recommend switching to eplerenone first to see if it goes away. I have seen men who underwent breast Bx and surgery on spiro to learn it all went away when sprio was stopped.CE Grim MD Do you have any more info what that "receptor" may be or where I might look to find more about it? I'm thinking of following up some more and see if I can identify a condition where Spironlactone might not be the idea solution. (May also identify good canidates for M2F transgender therapy!) I checked with Chaz , but he went the wrong way-he my be a resource if I decide to undo everything! ;>) I'm doing some of this follow on because I fully intend to make some changes that affected my treatment. (Atleast people will know how I feel!) I really think spironlactone is the wrong first line drug to treat PA. I know there were a few fathers that would have liked to reduce my testosterone back in the 60's but that has been less of a problem since I turned 60! I'm unsure how the women feel about it and if they appreciate the extra available estrogen but opinions are welcome! (I thought of testing my theory on my wife but I'd be in deep shit if my theory is correct!) I'm also following the direction of my PCP to the letter regarding the treatment of the gynocomastia since that is part of the overall cost of treatment. I have already contacted Sen. Bernie ' office regarding the sexual descrimination issue. (Female vets are guaranteed a Mammogram in <50 miles and I have to travel over 400 miles and probably loose 2 days!) If he can't resolve this issue, I bet I can find someone to file class action suit! - 65 yo super ob. male - 12mm X 13mm rt. a.adnoma with previous rt. flank pain. Treating with Meds. And DASH. . Current BP(last week ave): 131/76 HR 60 Other Issues/Opportunities: OSA w Bi-Pap settings 13/19, DM2, and PTSD. Meds: Duloxetine hcl 80 MG, Metoprolol Tartrate 200 MG, 81mg asprin, Metformin 2000MG and Spironolactone 50 MG. > > > > > > > > > > > > > > > > > > > > > Dr. Grim > > > > > > > > > > > > > > > > > > > > > > Do you have any experience treating PTNs w/ > > spironlactone > > > > > > who develop gynocomastia and breast tumors? I am specifically > > > > > > interested in the effect on Estrogen and Testosterone in > > males and > > > > > > preparing for a CTJ (Come To Jesus) meeting with the VA in the > > > > > > morning. > > > > > > > > > > > > > > > > > > > > > > - 65 yo super ob. male - 12mm X 13mm rt. > > a.adnoma > > > > > > with previous rt. flank pain. Treating with Meds. And DASH. . > > > > > > Current BP(last week ave): 131/76 HR 60 > > > > > > > > > > > Other Issues/Opportunities: OSA w Bi-Pap settings > > 13/19, > > > > > > DM2, and PTSD. > > > > > > > > > > > Meds: Duloxetine hcl 80 MG, Metoprolol Tartrate > > 200 MG, > > > > > > 81mg asprin, Metformin 2000MG and Spironolactone 50 MG. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 2, 2011 Report Share Posted December 2, 2011 I wasn't too sucessful finding info that I understood. (I suspect there might be some info there but a better medical knowledge would be required to understand it. I did find this statement, " Breast cancer in men, although rare, can lead to similar breast growth as is common with other Gynecomastia causes. Other cysts, growths, and clotted blood can all be cause of Gynecomastia since such occurrences in the breast area would lead to the appearance of woman like breasts. Generally these are more common where the symptoms are apparent in only one breast. " That is one area that concerns me since rt. breast = 5 bumps and rt lymph node = atleast one while nothing on the left side or breast. In fact I'm beginning to wonder if there is anything to the fact that everything is on my right side, ie: Adrenal adnoma, previous pain to rt flank and testis and now breast bumps. Any ideas? - 65 yo super ob. male - 12mm X 13mm rt. a.adnoma with previous rt. flank pain. Treating with Meds. And DASH. . Current BP(last week ave): 131/76 HR 60 Other Issues/Opportunities: OSA w Bi-Pap settings 13/19, DM2, and PTSD. Meds: Duloxetine hcl 80 MG, Metoprolol Tartrate 200 MG, 81mg asprin, Metformin 2000MG and Spironolactone 50 MG. > > > > > > > > > > > > > > > > > > > > > > > > > Dr. Grim > > > > > > > > > > > > > > > > > > > > > > > > > > Do you have any experience treating PTNs w/ > > > > spironlactone > > > > > > > > who develop gynocomastia and breast tumors? I am > > specifically > > > > > > > > interested in the effect on Estrogen and Testosterone in > > > > males and > > > > > > > > preparing for a CTJ (Come To Jesus) meeting with the VA > > in the > > > > > > > > morning. > > > > > > > > > > > > > > > > > > > > > > > > > > - 65 yo super ob. male - 12mm X 13mm rt. > > > > a.adnoma > > > > > > > > with previous rt. flank pain. Treating with Meds. And > > DASH. . > > > > > > > > Current BP(last week ave): 131/76 HR 60 > > > > > > > > > > > > > Other Issues/Opportunities: OSA w Bi-Pap > > settings > > > > 13/19, > > > > > > > > DM2, and PTSD. > > > > > > > > > > > > > Meds: Duloxetine hcl 80 MG, Metoprolol Tartrate > > > > 200 MG, > > > > > > > > 81mg asprin, Metformin 2000MG and Spironolactone 50 MG. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 2, 2011 Report Share Posted December 2, 2011 I would say chance. So chances of having L adrenal problem is say 1/2 and chances of having L breast problem is 1/2. Say pain on L side risk is 1/2 the chance of all three on same side would be 1/2 x 1/2 x 1/2 = 1/8 or 1 in 12.5 so pretty likely due to chance IMHO. May your pressure be low!CE Grim MS, MDSpecializing in DifficultHypertension I wasn't too sucessful finding info that I understood. (I suspect there might be some info there but a better medical knowledge would be required to understand it. I did find this statement, "Breast cancer in men, although rare, can lead to similar breast growth as is common with other Gynecomastia causes. Other cysts, growths, and clotted blood can all be cause of Gynecomastia since such occurrences in the breast area would lead to the appearance of woman like breasts. Generally these are more common where the symptoms are apparent in only one breast." That is one area that concerns me since rt. breast = 5 bumps and rt lymph node = atleast one while nothing on the left side or breast. In fact I'm beginning to wonder if there is anything to the fact that everything is on my right side, ie: Adrenal adnoma, previous pain to rt flank and testis and now breast bumps. Any ideas? - 65 yo super ob. male - 12mm X 13mm rt. a.adnoma with previous rt. flank pain. Treating with Meds. And DASH. . Current BP(last week ave): 131/76 HR 60 Other Issues/Opportunities: OSA w Bi-Pap settings 13/19, DM2, and PTSD. Meds: Duloxetine hcl 80 MG, Metoprolol Tartrate 200 MG, 81mg asprin, Metformin 2000MG and Spironolactone 50 MG. > > > > > > > > > > > > > > > > > > > > > > > > > Dr. Grim > > > > > > > > > > > > > > > > > > > > > > > > > > Do you have any experience treating PTNs w/ > > > > spironlactone > > > > > > > > who develop gynocomastia and breast tumors? I am > > specifically > > > > > > > > interested in the effect on Estrogen and Testosterone in > > > > males and > > > > > > > > preparing for a CTJ (Come To Jesus) meeting with the VA > > in the > > > > > > > > morning. > > > > > > > > > > > > > > > > > > > > > > > > > > - 65 yo super ob. male - 12mm X 13mm rt. > > > > a.adnoma > > > > > > > > with previous rt. flank pain. Treating with Meds. And > > DASH. . > > > > > > > > Current BP(last week ave): 131/76 HR 60 > > > > > > > > > > > > > Other Issues/Opportunities: OSA w Bi-Pap > > settings > > > > 13/19, > > > > > > > > DM2, and PTSD. > > > > > > > > > > > > > Meds: Duloxetine hcl 80 MG, Metoprolol Tartrate > > > > 200 MG, > > > > > > > > 81mg asprin, Metformin 2000MG and Spironolactone 50 MG. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
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