RE: Re: Conservation management of OCD

[Guest guest]

Thanks for all of the info. thus far. My understanding is that $$ is the

limiting factor, as they cannot afford the surgery.

>

>Reply-To: VetRehab

>To: VetRehab

>Subject: Re: Conservation management of OCD

>Date: Wed, 11 Apr 2007 01:12:42 -0000

>

>Hey guys,

>

>I am a bit confused on the use of Adequan for the treatment of OCD?

>I can see how Adequan may mask the pain/clinical signs associated

>with the lesion due to the anti-inflammatory effects of the

>chondroitin sulfate, however, how does it treat the lesion. Since an

>OCD lesion is due to a failure of endochondral ossification I do not

>see how this product allows for " reattachment " of the flap, or

>resorption of the lesion? My concern for dogs not treated with OCD

>lesions would be the secondary progression of OA and the potential

>for the flap to break free and migrate into the bicipital groove

>causing secondary conditions (such as bicipital tenosynovitis).

>Sorry, I have not had time to read this entire e-mail trail but why

>not take this patient to surgery…..arthroscopically it will take 15

>minutes and the dog will make a full recovery in 6 to 8 weeks?

>

>Sherman

>

>

>Sherman O. Canapp, Jr., DVM, MS

>

>Diplomate ACVS

>

>Veterinary Orthopedic & Sports Medicine Group

>

>10270 Baltimore National Pike

>

>Ellicott City, MD 21042

>

>

>

> (fax)

>

>www.vosm.org

>

>

>

>

>

_________________________________________________________________

Need a break? Find your escape route with Live Search Maps.

http://maps.live.com/?icid=hmtag3

[Guest guest]

Hi all,

I hope no one gave the impression that we thought Adequan would cure or fix

and OCD lesion, especially not me. I simply think that it will help.

There is no Chondroitin sulfate in Adequan, there is only Polysulfated

glycosaminoglycans.

My understanding is that Adequan inhibits many of the catabolic enzymes,

while having positive anabolic effects such as synthesis of proteins,

collagen, proteoglycans and hylauronic acid within the joint. I am pretty

sure that Adequan has a predilection for diseased cartilage sites, so it

makes sense to me that it would help the area of the OCD defect. I

understand and agree with Sherman that surgery is the best option, but also

know the reality of $$$ challenged clients.

Good luck,

Pam Nichols

Re: Conservation management of OCD

>Date: Wed, 11 Apr 2007 01:12:42 -0000

>

>Hey guys,

>

>I am a bit confused on the use of Adequan for the treatment of OCD?

>I can see how Adequan may mask the pain/clinical signs associated

>with the lesion due to the anti-inflammatory effects of the

>chondroitin sulfate, however, how does it treat the lesion. Since an

>OCD lesion is due to a failure of endochondral ossification I do not

>see how this product allows for " reattachment " of the flap, or

>resorption of the lesion? My concern for dogs not treated with OCD

>lesions would be the secondary progression of OA and the potential

>for the flap to break free and migrate into the bicipital groove

>causing secondary conditions (such as bicipital tenosynovitis).

>Sorry, I have not had time to read this entire e-mail trail but why

>not take this patient to surgery...arthroscopically it will take 15

>minutes and the dog will make a full recovery in 6 to 8 weeks?

>

>Sherman

>

>

>Sherman O. Canapp, Jr., DVM, MS

>

>Diplomate ACVS

>

>Veterinary Orthopedic & Sports Medicine Group

>

>10270 Baltimore National Pike

>

>Ellicott City, MD 21042

>

>

>

> (fax)

>

>www.vosm.org

>

>

>

>

>

_________________________________________________________________

Need a break? Find your escape route with Live Search Maps.

http://maps.live.com/?icid=hmtag3

[Guest guest]

Very cool, I should have said “to my

knowledge” there is no chondroitin sulfate in Adequan! Whatever the

molecule, I think Adequan will make a difference! Do you think it will or do

you think the only route is surgery? Thanks for the clarification!

Pam

From: VetRehab [mailto:VetRehab ] On Behalf Of shermancanapp

Sent: Wednesday, April 11, 2007

8:39 AM

To: VetRehab

Subject: Re:

Conservation management of OCD

Pam,

Actually a PSGAG is a chondroitin sulfate molecule.....my masters

research was in osteoarthritis and I had to memorize these

molecules. Specifically, Polysulfated glycosaminoglycans is a semi-

synthetic glycosaminoglycan prepared by extracting GAGs from bovine

tracheal cartilage. GAGs are polysaccharides composed or repeating

disaccharide units. The GAG present in PSGAG (Adequan) is

principally Chondroitin Sulfate containing 3 to 4 sulfate esters per

disaccharide unit. Therefore, the active ingredient in Adequan is

actually Chondroitin Sulfate.

You can find this same information on the Adequan insert.

Cheers,

Sherman

>

> Hi all,

> I hope no one gave the impression that we thought Adequan would

cure or fix

> and OCD lesion, especially not me. I simply think that it will

help.

>

> There is no Chondroitin sulfate in Adequan, there is only

Polysulfated

> glycosaminoglycans.

>

> My understanding is that Adequan inhibits many of the catabolic

enzymes,

> while having positive anabolic effects such as synthesis of

proteins,

> collagen, proteoglycans and hylauronic acid within the joint. I am

pretty

> sure that Adequan has a predilection for diseased cartilage sites,

so it

> makes sense to me that it would help the area of the OCD defect. I

> understand and agree with Sherman

that surgery is the best option,

but also

> know the reality of $$$ challenged clients.

> Good luck,

> Pam Nichols

>

> Re: Conservation management of OCD

> >Date: Wed, 11 Apr 2007 01:12:42 -0000

> >

> >Hey guys,

> >

> >I am a bit confused on the use of Adequan for the treatment of OCD?

> >I can see how Adequan may mask the pain/clinical signs associated

> >with the lesion due to the anti-inflammatory effects of the

> >chondroitin sulfate, however, how does it treat the lesion. Since

an

> >OCD lesion is due to a failure of endochondral ossification I do

not

> >see how this product allows for " reattachment " of the flap,

or

> >resorption of the lesion? My concern for dogs not treated with OCD

> >lesions would be the secondary progression of OA and the potential

> >for the flap to break free and migrate into the bicipital groove

> >causing secondary conditions (such as bicipital tenosynovitis).

> >Sorry, I have not had time to read this entire e-mail trail but why

> >not take this patient to surgery...arthroscopically it will take

15

> >minutes and the dog will make a full recovery in 6 to 8 weeks?

> >

> >Sherman

> >

> >

> >Sherman O. Canapp, Jr., DVM, MS

> >

> >Diplomate ACVS

> >

> >Veterinary Orthopedic & Sports Medicine Group

> >

> >10270 Baltimore National Pike

> >

> >Ellicott City, MD 21042

> >

> >

> >

> > (fax)

> >

> >www.vosm.org

> >

> >

> >

> >

> >

>

> __________________________________________________________

> Need a break? Find your escape route with Live Search Maps.

> http://maps.live.com/?icid=hmtag3

>

>

>

>

>

[Guest guest]

One more thing! Sherman, do you use an oral Glucosamine

and chondroitin supplement? I have no great experience using them but would

love to hear!

Pam

From: VetRehab [mailto:VetRehab ] On Behalf Of shermancanapp

Sent: Wednesday, April 11, 2007

8:39 AM

To: VetRehab

Subject: Re:

Conservation management of OCD

Pam,

Actually a PSGAG is a chondroitin sulfate molecule.....my masters

research was in osteoarthritis and I had to memorize these

molecules. Specifically, Polysulfated glycosaminoglycans is a semi-

synthetic glycosaminoglycan prepared by extracting GAGs from bovine

tracheal cartilage. GAGs are polysaccharides composed or repeating

disaccharide units. The GAG present in PSGAG (Adequan) is

principally Chondroitin Sulfate containing 3 to 4 sulfate esters per

disaccharide unit. Therefore, the active ingredient in Adequan is

actually Chondroitin Sulfate.

You can find this same information on the Adequan insert.

Cheers,

Sherman

>

> Hi all,

> I hope no one gave the impression that we thought Adequan would

cure or fix

> and OCD lesion, especially not me. I simply think that it will

help.

>

> There is no Chondroitin sulfate in Adequan, there is only

Polysulfated

> glycosaminoglycans.

>

> My understanding is that Adequan inhibits many of the catabolic

enzymes,

> while having positive anabolic effects such as synthesis of

proteins,

> collagen, proteoglycans and hylauronic acid within the joint. I am

pretty

> sure that Adequan has a predilection for diseased cartilage sites,

so it

> makes sense to me that it would help the area of the OCD defect. I

> understand and agree with Sherman

that surgery is the best option,

but also

> know the reality of $$$ challenged clients.

> Good luck,

> Pam Nichols

>

> Re: Conservation management of OCD

> >Date: Wed, 11 Apr 2007 01:12:42 -0000

> >

> >Hey guys,

> >

> >I am a bit confused on the use of Adequan for the treatment of OCD?

> >I can see how Adequan may mask the pain/clinical signs associated

> >with the lesion due to the anti-inflammatory effects of the

> >chondroitin sulfate, however, how does it treat the lesion. Since

an

> >OCD lesion is due to a failure of endochondral ossification I do

not

> >see how this product allows for " reattachment " of the flap,

or

> >resorption of the lesion? My concern for dogs not treated with OCD

> >lesions would be the secondary progression of OA and the potential

> >for the flap to break free and migrate into the bicipital groove

> >causing secondary conditions (such as bicipital tenosynovitis).

> >Sorry, I have not had time to read this entire e-mail trail but why

> >not take this patient to surgery...arthroscopically it will take

15

> >minutes and the dog will make a full recovery in 6 to 8 weeks?

> >

> >Sherman

> >

> >

> >Sherman O. Canapp, Jr., DVM, MS

> >

> >Diplomate ACVS

> >

> >Veterinary Orthopedic & Sports Medicine Group

> >

> >10270 Baltimore National Pike

> >

> >Ellicott City, MD 21042

> >

> >

> >

> > (fax)

> >

> >www.vosm.org

> >

> >

> >

> >

> >

>

> __________________________________________________________

> Need a break? Find your escape route with Live Search Maps.

> http://maps.live.com/?icid=hmtag3

>

>

>

>

>

[Guest guest]

Sherman,

Do you ever use legend IV in dogs?

What kinds of cases are you using IA Legend?

I am doing IA injections of orthokine (Courtesy of Chad Devitt at VRCC in Denver) in the elbows of two Bernese Mountain

dogs post surgically. Would that be a case for Legend?

Thanks for the info!

Pam

From: VetRehab [mailto:VetRehab ] On Behalf Of shermancanapp

Sent: Wednesday, April 11, 2007

10:09 AM

To: VetRehab

Subject: Re:

Conservation management of OCD

Pam,

I am huge believer in oral supplements, in particular glucosamine and

chondroitin sulfate. Specifically, Cosequin has worked very well for

our patients; however, with the new Dasuquin product I have been even

more impressed. Like Marti, I frequently reach for IA products

(HA). Because there are no HA products labeled for the canine you

will have to use the product extra label, however, to date, we have

had zero adverse reactions. We use the Legend product (Bayer Animal

Health) with the protocol being 1 injection weekly for 3 weeks.

Unfortunately, unlike in humans and horses, dogs require a heavy

sedation or brief anesthetic episode for the injections (it stings

and dogs will not tolerate intra-articular injections). With that

being said, a series of IA HA injections with anesthesia and oral

supplements have you almost to the price of arthroscopy.

Sherman

Sherman O. Canapp, Jr., DVM, MS

Diplomate ACVS

Veterinary Orthopedic & Sports Medicine Group

10270 Baltimore National Pike

Ellicott City, MD 21042

(fax)

www.vosm.org

________________________________________

> >

> > Hi all,

> > I hope no one gave the impression that we thought Adequan would

> cure or fix

> > and OCD lesion, especially not me. I simply think that it will

> help.

> >

> > There is no Chondroitin sulfate in Adequan, there is only

> Polysulfated

> > glycosaminoglycans.

> >

> > My understanding is that Adequan inhibits many of the catabolic

> enzymes,

> > while having positive anabolic effects such as synthesis of

> proteins,

> > collagen, proteoglycans and hylauronic acid within the joint. I

am

> pretty

> > sure that Adequan has a predilection for diseased cartilage

sites,

> so it

> > makes sense to me that it would help the area of the OCD defect. I

> > understand and agree with Sherman

that surgery is the best

option,

> but also

> > know the reality of $$$ challenged clients.

> > Good luck,

> > Pam Nichols

> >

> > Re: Conservation management of OCD

> > >Date: Wed, 11 Apr 2007 01:12:42 -0000

> > >

> > >Hey guys,

> > >

> > >I am a bit confused on the use of Adequan for the treatment of

OCD?

> > >I can see how Adequan may mask the pain/clinical signs associated

> > >with the lesion due to the anti-inflammatory effects of the

> > >chondroitin sulfate, however, how does it treat the lesion.

Since

> an

> > >OCD lesion is due to a failure of endochondral ossification I do

> not

> > >see how this product allows for " reattachment " of the

flap, or

> > >resorption of the lesion? My concern for dogs not treated with

OCD

> > >lesions would be the secondary progression of OA and the

potential

> > >for the flap to break free and migrate into the bicipital groove

> > >causing secondary conditions (such as bicipital tenosynovitis).

> > >Sorry, I have not had time to read this entire e-mail trail but

why

> > >not take this patient to surgery...arthroscopically it will

take

15

> > >minutes and the dog will make a full recovery in 6 to 8 weeks?

> > >

> > >Sherman

> > >

> > >

> > >Sherman O. Canapp, Jr., DVM, MS

> > >

> > >Diplomate ACVS

> > >

> > >Veterinary Orthopedic & Sports Medicine Group

> > >

> > >10270 Baltimore National Pike

> > >

> > >Ellicott City,

MD 21042

> > >

> > >

> > >

> > > (fax)

> > >

> > >www.vosm.org

> > >

> > >

> > >

> > >

> > >

> >

> > __________________________________________________________

> > Need a break? Find your escape route with Live Search Maps.

> > http://maps. <http://maps.live.com/?icid=hmtag3>

live.com/?

icid=hmtag3

> >

> >

> >

> >

> >

[Guest guest]

Hi, I have been using TrixSyn (they have a web site), new oral form for canine/feline of hyaluronate. I have been using this product for about a year now with excellent results. Prior to this being out, I was injecting also. I am in agreement with Sherman onthe OCD arthroscopy then follow up with rehab. Sherman DVMmancanapp wrote: Pam,I am huge believer in oral

supplements, in particular glucosamine and chondroitin sulfate. Specifically, Cosequin has worked very well for our patients; however, with the new Dasuquin product I have been even more impressed. Like Marti, I frequently reach for IA products (HA). Because there are no HA products labeled for the canine you will have to use the product extra label, however, to date, we have had zero adverse reactions. We use the Legend product (Bayer Animal Health) with the protocol being 1 injection weekly for 3 weeks. Unfortunately, unlike in humans and horses, dogs require a heavy sedation or brief anesthetic episode for the injections (it stings and dogs will not tolerate intra-articular injections). With that being said, a series of IA HA injections with anesthesia and oral supplements have you almost to the price of arthroscopy.ShermanSherman O. Canapp, Jr., DVM, MSDiplomate ACVSVeterinary Orthopedic &

Sports Medicine Group10270 Baltimore National PikeEllicott City, MD 21042 (fax)www.vosm.org________________________________________--- In VetRehab , "Dr. Pam Nichols" wrote:>> One more thing! Sherman, do you use an oral Glucosamine and chondroitin> supplement? I have no great experience using them but would love to hear! > > Pam> > > > _____ > > From: VetRehab [mailto:VetRehab ] On Behalf> Of shermancanapp> Sent: Wednesday, April 11, 2007 8:39 AM> To: VetRehab > Subject: Re: Conservation

management of OCD> > > > Pam,> > Actually a PSGAG is a chondroitin sulfate molecule.....my masters > research was in osteoarthritis and I had to memorize these > molecules. Specifically, Polysulfated glycosaminoglycans is a semi-> synthetic glycosaminoglycan prepared by extracting GAGs from bovine > tracheal cartilage. GAGs are polysaccharides composed or repeating > disaccharide units. The GAG present in PSGAG (Adequan) is > principally Chondroitin Sulfate containing 3 to 4 sulfate esters per > disaccharide unit. Therefore, the active ingredient in Adequan is > actually Chondroitin Sulfate.> > You can find this same information on the Adequan insert.> > Cheers,> > Sherman> > > >> > Hi all, > > I hope no one gave the impression that we thought Adequan would > cure or fix> > and OCD lesion, especially not me. I simply think that it will > help.> > > > There is no Chondroitin sulfate in Adequan, there is only > Polysulfated> > glycosaminoglycans. > > > > My understanding is that Adequan inhibits many of the catabolic > enzymes,> > while having positive anabolic effects such as synthesis of > proteins,> > collagen, proteoglycans and hylauronic acid within the joint. I am > pretty> > sure that Adequan has a predilection for diseased cartilage sites, > so it> > makes sense to me that it would help the area of the OCD defect. I> > understand and agree with Sherman that surgery is the best option, > but also> > know the reality of

$$$ challenged clients. > > Good luck, > > Pam Nichols > > > > Re: Conservation management of OCD> > >Date: Wed, 11 Apr 2007 01:12:42 -0000> > >> > >Hey guys,> > >> > >I am a bit confused on the use of Adequan for the treatment of OCD?> > >I can see how Adequan may mask the pain/clinical signs associated> > >with the lesion due to the anti-inflammatory effects of the> > >chondroitin sulfate, however, how does it treat the lesion. Since > an> > >OCD lesion is due to a failure of endochondral ossification I do > not> > >see how this product allows for "reattachment" of the flap, or> > >resorption of the lesion? My concern for dogs not treated with OCD> > >lesions would be the secondary progression of OA and the potential> >

>for the flap to break free and migrate into the bicipital groove> > >causing secondary conditions (such as bicipital tenosynovitis).> > >Sorry, I have not had time to read this entire e-mail trail but why> > >not take this patient to surgery...arthroscopically it will take 15> > >minutes and the dog will make a full recovery in 6 to 8 weeks?> > >> > >Sherman> > >> > >> > >Sherman O. Canapp, Jr., DVM, MS> > >> > >Diplomate ACVS> > >> > >Veterinary Orthopedic & Sports Medicine Group> > >> > >10270 Baltimore National Pike> > >> > >Ellicott City, MD 21042> > >> > >> > >> > > (fax)> > >> > >www.vosm.org> > >> >

>> > >> > >> > >> > > > __________________________________________________________> > Need a break? Find your escape route with Live Search Maps. > > http://maps. <http://maps.live.com/?icid=hmtag3> live.com/?icid=hmtag3> > > > > > > > > >

[Guest guest]

For those who are believers in oral HA - Equine

Lubrisyn now makes a canine formula. I believe the

TrixSyn manufacturer used to work for Lubrisyn and

went out on his own. They will send you free samples.

Mindy , DVM

--- john sherman wrote:

> Hi,

>

> I have been using TrixSyn (they have a web site),

> new oral form for canine/feline of hyaluronate. I

> have been using this product for about a year now

> with excellent results. Prior to this being out, I

> was injecting also.

>

> I am in agreement with Sherman onthe OCD

> arthroscopy then follow up with rehab.

>

> Sherman DVM

>

> mancanapp wrote:

> Pam,

>

> I am huge believer in oral supplements, in

> particular glucosamine and

> chondroitin sulfate. Specifically, Cosequin has

> worked very well for

> our patients; however, with the new Dasuquin product

> I have been even

> more impressed. Like Marti, I frequently reach for

> IA products

> (HA). Because there are no HA products labeled for

> the canine you

> will have to use the product extra label, however,

> to date, we have

> had zero adverse reactions. We use the Legend

> product (Bayer Animal

> Health) with the protocol being 1 injection weekly

> for 3 weeks.

> Unfortunately, unlike in humans and horses, dogs

> require a heavy

> sedation or brief anesthetic episode for the

> injections (it stings

> and dogs will not tolerate intra-articular

> injections). With that

> being said, a series of IA HA injections with

> anesthesia and oral

> supplements have you almost to the price of

> arthroscopy.

>

> Sherman

>

> Sherman O. Canapp, Jr., DVM, MS

> Diplomate ACVS

> Veterinary Orthopedic & Sports Medicine Group

> 10270 Baltimore National Pike

> Ellicott City, MD 21042

>

> (fax)

> www.vosm.org

> ________________________________________

>

>

> > >

> > > Hi all,

> > > I hope no one gave the impression that we

> thought Adequan would

> > cure or fix

> > > and OCD lesion, especially not me. I simply

> think that it will

> > help.

> > >

> > > There is no Chondroitin sulfate in Adequan,

> there is only

> > Polysulfated

> > > glycosaminoglycans.

> > >

> > > My understanding is that Adequan inhibits many

> of the catabolic

> > enzymes,

> > > while having positive anabolic effects such as

> synthesis of

> > proteins,

> > > collagen, proteoglycans and hylauronic acid

> within the joint. I

> am

> > pretty

> > > sure that Adequan has a predilection for

> diseased cartilage

> sites,

> > so it

> > > makes sense to me that it would help the area of

> the OCD defect. I

> > > understand and agree with Sherman that surgery

> is the best

> option,

> > but also

> > > know the reality of $$$ challenged clients.

> > > Good luck,

> > > Pam Nichols

> > >

> > > Re: Conservation management

> of OCD

> > > >Date: Wed, 11 Apr 2007 01:12:42 -0000

> > > >

> > > >Hey guys,

> > > >

> > > >I am a bit confused on the use of Adequan for

> the treatment of

> OCD?

> > > >I can see how Adequan may mask the

> pain/clinical signs associated

> > > >with the lesion due to the anti-inflammatory

> effects of the

> > > >chondroitin sulfate, however, how does it treat

> the lesion.

> Since

> > an

> > > >OCD lesion is due to a failure of endochondral

> ossification I do

> > not

> > > >see how this product allows for " reattachment "

> of the flap, or

>

=== message truncated ===

________________________________________________________________________________\

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[Guest guest]

Hi Sherman,

Would IA HA be helpful in stifles? Perhaps

even months or years after surgery when OA is present? I have not used oral

HA or IV Legend in dogs, but I use IV legend routinely in my horses. Would love

to hear your thoughts.

Pam

From: VetRehab [mailto:VetRehab ] On Behalf Of shermancanapp

Sent: Wednesday, April 11, 2007

12:10 PM

To: VetRehab

Subject: Re:

Conservation management of OCD

Pam,

I performed a large (over 100 dogs) placebo controlled, double

blinded, clinical trial while at UF evaluating the effects of IV HA

on dogs. We evaluated cytokines within serum/plasma, synovial fluid

cytokines, and synovial fluid viscosity. Unfortunately, the use of

IVHA had no significant effect when compared to placebo on dogs.

This paper can be found in VCOT 2005 under Canapp et al. This paper

was also presented at ACVS and VOS.

While I am aware well of oral HA products, to date, none have been

evaluated for bioavailability and efficacy. Another words, do they

make it to the joint and are they taken up within the joint? I have

a hard time believing that if the IV HA products had no effect that

an oral HA product would, however, as you all know I am very open

minded and anything is possible….I would just like some objective

data before I have clients spend money on untested products.

Unfortunately, I am not familiar with the orthokine product, however,

a Berner with elbow OA would be a good example of appropriate case

selection……typically I follow post-op elbows up with NSAIDs,

Adequan,

Dasuquan, and rehab…….down the road if the OA progresses, I will

hit

them with a series of IAHA (not immediately post-op).

Hope this helps.

Sherman

Sherman O. Canapp, Jr., DVM, MS

Diplomate ACVS

Veterinary Orthopedic & Sports Medicine Group

10270 Baltimore National Pike

Ellicott City, MD 21042

(fax)

www.vosm.org

________________________________________

> > >

> > > Hi all,

> > > I hope no one gave the impression that we thought Adequan would

> > cure or fix

> > > and OCD lesion, especially not me. I simply think that it will

> > help.

> > >

> > > There is no Chondroitin sulfate in Adequan, there is only

> > Polysulfated

> > > glycosaminoglycans.

> > >

> > > My understanding is that Adequan inhibits many of the catabolic

> > enzymes,

> > > while having positive anabolic effects such as synthesis of

> > proteins,

> > > collagen, proteoglycans and hylauronic acid within the joint. I

> am

> > pretty

> > > sure that Adequan has a predilection for diseased cartilage

> sites,

> > so it

> > > makes sense to me that it would help the area of the OCD

defect. I

> > > understand and agree with Sherman

that surgery is the best

> option,

> > but also

> > > know the reality of $$$ challenged clients.

> > > Good luck,

> > > Pam Nichols

> > >

> > > Re: Conservation management of OCD

> > > >Date: Wed, 11 Apr 2007 01:12:42 -0000

> > > >

> > > >Hey guys,

> > > >

> > > >I am a bit confused on the use of Adequan for the treatment

of

> OCD?

> > > >I can see how Adequan may mask the pain/clinical signs

associated

> > > >with the lesion due to the anti-inflammatory effects of the

> > > >chondroitin sulfate, however, how does it treat the lesion.

> Since

> > an

> > > >OCD lesion is due to a failure of endochondral ossification

I

do

> > not

> > > >see how this product allows for " reattachment " of

the flap, or

> > > >resorption of the lesion? My concern for dogs not treated

with

> OCD

> > > >lesions would be the secondary progression of OA and the

> potential

> > > >for the flap to break free and migrate into the bicipital

groove

> > > >causing secondary conditions (such as bicipital tenosynovitis).

> > > >Sorry, I have not had time to read this entire e-mail trail

but

> why

> > > >not take this patient to surgery...arthroscopically it

will

take

> 15

> > > >minutes and the dog will make a full recovery in 6 to 8

weeks?

> > > >

> > > >Sherman

> > > >

> > > >

> > > >Sherman O. Canapp, Jr., DVM, MS

> > > >

> > > >Diplomate ACVS

> > > >

> > > >Veterinary Orthopedic & Sports Medicine Group

> > > >

> > > >10270 Baltimore National Pike

> > > >

> > > >Ellicott City,

MD 21042

> > > >

> > > >

> > > >

> > > > (fax)

> > > >

> > > >www.vosm.org

> > > >

> > > >

> > > >

> > > >

> > > >

> > >

> > > __________________________________________________________

> > > Need a break? Find your escape route with Live Search Maps.

> > > http://maps. <http://maps. <http://maps.live.com/?icid=hmtag3>

> live.com/?icid=hmtag3> live.com/?

> icid=hmtag3

> > >

> > >

> > >

> > >

> > >