zetia/ezetimibe/ezetrol HEALTH CANADA WARNING

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http://www.hc-sc.gc.ca/hpfb-dgpsa/tpd-dpt/ezetrol_hpc_e.html

February 1, 2005

Subject: Association of Ezetrol® (ezetimibe) with myalgia,

rhabdomyolysis, hepatitis, pancreatitis, and thrombocytopenia

Dear Health Care Professional,

Merck Frosst/Schering Pharmaceuticals, following discussions with

Health Canada, would like to inform you of new safety data for

Ezetrol® (ezetimibe), used alone or in combination with a statin.

Ezetimibe is a cholesterol absorption inhibitor that is classified as a

systemic drug, because of the enterohepatic recirculation of one of its

metabolites1.

The Product Monograph for Ezetrol® (ezetimibe)

[Guest guest]

February 1, 2005Subject: Association of Ezetrol® (ezetimibe) with myalgia,rhabdomyolysis, hepatitis, pancreatitis, and thrombocytopeniaDear Health Care Professional,Merck Frosst/Schering Pharmaceuticals, following discussions withHealth Canada, would like to inform you of new safety data forEzetrol® (ezetimibe), used alone or in combination with a statin.Ezetimibe is a cholesterol absorption inhibitor that is classified as asystemic drug, because of the enterohepatic recirculation of one of itsmetabolites1.The Product Monograph for Ezetrol® (ezetimibe)

Thank you ! This is the same one the cardiologist wants me to take, now that I refused flat out to ever take a statin again !!I printed out the Crestor adverse reactions, and I'll do the same with this one , too . Without us looking out for each other ,where would we be ! Thanks again !

Les .