Ulcerative colitis/Rectal irrigation

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Here's one of the studies on Butyrate administration I referred to earlier.Dig Dis Sci. 1991 Feb;36(2):185-7.Rectal irrigation with short-chain fatty acids for distal ulcerative colitis. Preliminary report.Breuer RI, Buto SK, Christ ML, Bean J, Vernia P, Paoluzi P, Di Paolo MC, Caprilli R.SourceDepartment of Medicine, ton Hospital, Illinois 60201.AbstractColon

cells from patients with ulcerative colitis utilize short-chain fatty acids inefficiently and may be exposed to decreased concentrations of these compounds. To test whether irrigation of the inflamed mucosa with short-chain fatty acids is useful, we conducted a six-week preliminary trial in 12 patients with distal colitis. Each patient used twice daily rectal irrigations with 100 ml of a solution containing acetate (80 mM),

propionate (30 mM), and butyrate (40 mM). Two patients stopped at three

weeks, one because of no improvement and the other because of complete resolution of symptoms. Of the 10 who completed the trial, nine were judged to be at least much improved and showed a change in a mean disease activity index score from 7.9 +/- 0.3 (SE) to 1.8 +/- 0.6 (SE) (P less than or equal to 0.002) and in a mucosal histology score from 7.7 +/- 0.7 (SE) to 2.6 +/- 0.7 (SE) (P less than or equal to 0.002). Thus, ulcerative colitis patients appear to benefit from increased contact with or higher than usual levels of these critical energy substrates.PMID:1988261 [PubMed - indexed for MEDLINE]

The more drastic treatments but VERY effective are: the poo transplant and eating parasite eggs. It looks like the first fixes it for good after a few treatments (according to research) and the second after a year of twice a month treatment (according to Antonucci)