Re: Building up for chelation- detox testing - SHARI

[Guest guest]

Shari and others,

How did you learn that one of your daughter's metabolizing (detoxification?)

pathways is blocked? Did you do a Great Smokies or Metametrix Detox panel?

I'm not sure I could get my son (5) to spit the saliva portion, but I really

want that information. Any tips?

Thanks, Abbie

Building up for chelation

>

>

> > How would you know if your child couldn't " handle " chelation. Some

> > dan docs are " building the kids up " to get to chelation. Is this

> > really possible when a child is full of metals? Our doc says that

> > our daughter will get very sick if we did it now. I know you need

> > to build up mineral status but how long should that take? For all

> > those experienced folks out there. What really has to be done and

> > how do you know you are ready for the plunge? If you have been

> > fighting the bowels forever should you just take the plunge?

> > Especially with TD-DMPS is this really necessary since it doesn't

> > fire up yeast. Or are there still potential yeast problems?

> > Thanks, Terri

> >

> >

> >

> >

> > Many frequently asked questions and answers can be found at

> <http://forums.autism-rxguidebook.com>

> >

[Guest guest]

Abbie,

I came up on it by chance. Our daughter had a terrible reaction to Strattera

and we suspected it was building up in her. I took the name of a place that

does genetic testing for prescription drugs to our pediatrician. We had her

blood drawn for the test and the results just came back. She is blocked

completely on 2D6, partially on 2C9 and 2C19 is o.k. This means that drugs

and other supplements are metabolized by certain pathways in the liver. I

still don't have near the information that I need, but I know now why she's

had trouble for years with certain medications. I want to find out now if

heavy metals go through the same pathways, and which foods go through the

pathways - if any. I'm just starting this, but I'll let you know when I find

out more. For instance, Tylenol is a drug that she can't metabolize. I just

always thought she acted too tired taking Tylenol so as- mother's instinct

- I never gave her Tylenol very much. So, now I know why. The test was

performed by Genelex. You can reach them at 1-800-test-DNA. It costs 750.00

for a prescription drug profile and a nutritional profile. I don't have the

results for that, yet.

Good luck,

Shari

Building up for chelation

> >

> >

> > > How would you know if your child couldn't " handle " chelation. Some

> > > dan docs are " building the kids up " to get to chelation. Is this

> > > really possible when a child is full of metals? Our doc says that

> > > our daughter will get very sick if we did it now. I know you need

> > > to build up mineral status but how long should that take? For all

> > > those experienced folks out there. What really has to be done and

> > > how do you know you are ready for the plunge? If you have been

> > > fighting the bowels forever should you just take the plunge?

> > > Especially with TD-DMPS is this really necessary since it doesn't

> > > fire up yeast. Or are there still potential yeast problems?

> > > Thanks, Terri

> > >

> > >

> > >

> > >

> > > Many frequently asked questions and answers can be found at

> > <http://forums.autism-rxguidebook.com>

> > >

[Guest guest]

Shari,

How amazing and fascinating. Is there anything much that can be done to open

up these pathways? Do you think mega quantities of milk thistle would affect

them? Or does anyone know?

Thanks, Abbie

Building up for chelation

> > >

> > >

> > > > How would you know if your child couldn't " handle " chelation. Some

> > > > dan docs are " building the kids up " to get to chelation. Is this

> > > > really possible when a child is full of metals? Our doc says that

> > > > our daughter will get very sick if we did it now. I know you need

> > > > to build up mineral status but how long should that take? For all

> > > > those experienced folks out there. What really has to be done and

> > > > how do you know you are ready for the plunge? If you have been

> > > > fighting the bowels forever should you just take the plunge?

> > > > Especially with TD-DMPS is this really necessary since it doesn't

> > > > fire up yeast. Or are there still potential yeast problems?

> > > > Thanks, Terri

> > > >

> > > >

> > > >

> > > >

> > > > Many frequently asked questions and answers can be found at

> > > <http://forums.autism-rxguidebook.com>

> > > >

[Guest guest]

I'm not sure. We're going to a geneticist to find out more.

It's really interesting.

Shari

Building up for chelation

> > > >

> > > >

> > > > > How would you know if your child couldn't " handle " chelation.

Some

> > > > > dan docs are " building the kids up " to get to chelation. Is this

> > > > > really possible when a child is full of metals? Our doc says that

> > > > > our daughter will get very sick if we did it now. I know you need

> > > > > to build up mineral status but how long should that take? For all

> > > > > those experienced folks out there. What really has to be done and

> > > > > how do you know you are ready for the plunge? If you have been

> > > > > fighting the bowels forever should you just take the plunge?

> > > > > Especially with TD-DMPS is this really necessary since it doesn't

> > > > > fire up yeast. Or are there still potential yeast problems?

> > > > > Thanks, Terri

> > > > >

> > > > >

> > > > >

> > > > >

> > > > > Many frequently asked questions and answers can be found at

> > > > <http://forums.autism-rxguidebook.com>

> > > > >

[Guest guest]

This is my first comment in this thread and I am going to

comment on the stuff in the same order it appears, so it

may be a little disjointed. I also deleted some

parts of the text -- leaving the parts I am commenting on.

Bear with me!

> How amazing and fascinating. Is there anything much that can be

done to open

> up these pathways? Do you think mega quantities of milk thistle

would affect

> them? Or does anyone know?

Milk thistle is generally pretty safe, is

really helpful for the liver, and can be used long term.

It is helpful for some " serious " liver diseases, so it seems

like a good idea to me. (I have been taking it every day

for the last few months and have no plan to stop.)

Milk thistle is generally pretty darn safe. In addition I

am continually saying that dosage range for herbs tends to

be quite wide. NONE THE LESS, the word " mega " in the

above query troubles me. Somewhat high amounts might

be okay. I'm not sure if I would use " mega " doses of

milk thistle on myself or not...... clearly I WOULD

use milk thistle continually for long periods.

> > Abbie,

> > I came up on it by chance. Our daughter had a terrible reaction

to

> Strattera

> > and we suspected it was building up in her. I took the name of a

place

> that

> > does genetic testing for prescription drugs to our pediatrician.

We had

> her

> > blood drawn for the test and the results just came back. She is

blocked

> > completely on 2D6, partially on 2C9 and 2C19 is o.k. This means

that drugs

> > and other supplements are metabolized by certain pathways in the

liver.

I guess I don't understand this comment. Drugs and anything

toxic is processed by the liver. (Livers work hard!)

When you say she is blocked completely, I think this would

mean that the liver is NOT processing things that it should

be. Maybe that's what you meant.

I

> > still don't have near the information that I need, but I know

now why

> she's

> > had trouble for years with certain medications. I want to find

out now if

> > heavy metals go through the same pathways, and which foods go

through the

> > pathways - if any.

I don't know anything about the pathway numbers you listed, or

what goes through which. But heavy metals certainly cause stress for

the liver in processing. Other things that are stressful for

the liver (again I don't know which pathways) include

pesticides, chemicals (e.g. in food, in the air, in body care

products), prescription medications, alcohol, hormones

(either those made by the body or hormones ingested in

commercial meat).

> > > > Our daughter had a rough time with her first round of

chelation using

> > > DMPS.

> > > > We chelated several years ago using DMSA with no results/

good nor

> bad.

another option you could consider is using alpha lipoic acid.

It is actually GOOD for the liver. Chelation itself is

still stressful to the liver (at least in someone who is

mercury toxic), because of the increased metal in the

blood.... but at least the chelation agent isn't adding

to it......

> > I

> > > > have sent her doctor the information about TD-DMPS. We know

that our

> > > > daughter is completely blocked on one of her metabolizing

pathways in

> > the

> > > > liver and another is 50% blocked which means certain

medications can

> > build

> > > > faster and cause greater toxicity. We just got her DNA

results on the

> > > liver

> > > > after we we chelated. Now, I'm going to find out if DMPS has

to go

> > through

> > > > one of her poor channels of the liver. I wonder if the

Transdermal

> > > by-passes

> > > > the liver altogether?

Personally, this does not sound possible to me. At least

not if the chelation is effective. If the DMPS is being

absorbed then the liver gets to clean it out of the

bloodstream. If it is not being absorbed then it is not

an issue (and it would also not chelate in that case).

> > > > > How would you know if your child couldn't " handle "

chelation. Some

> > > > > dan docs are " building the kids up " to get to chelation.

Is this

> > > > > really possible when a child is full of metals?

only somewhat.

Our doc says that

> > > > > our daughter will get very sick if we did it now. I know

you need

> > > > > to build up mineral status but how long should that take?

a couple of weeks?

For all

> > > > > those experienced folks out there. What really has to be

done and

> > > > > how do you know you are ready for the plunge?

like everything else about chelation, there seems to be

many answers to this, including lots of strong convictions.

good wishes,

Moria