Re: airborne molds (response to Abbie - long)

[Guest guest]

Kathy,

Hmmm. Thank you! Lots to think about and lots to askmy doctor about.

Abbie

yeast not excessive, but child responds to

> antifungals; regressions during pollen seasons

>

>

> > During a conversation at the recent DAN! in Mclean, Va, Jim

Neubrander,

> > M.D.,

> > offered a fascinating model for understanding why some autistic kids

> > show no elevated yeast via CDSA but show positive response to

antifungals.

> >

> > Here is my rendition of Jim's hypothetical offering:

> >

> > A. Virtually everyone has yeast, and most healthy people would test

low

> > for Candida species on a CDSA.

> >

> > B. Jim and other docs have reported that some autistic kids regress

> > (mildly?) during times of pollen, an observation that links immune

> > reactions to regressions.

> >

> > C. Jim offered that perhaps the low-yeast-on-CDSA kids who improve via

> > an antifungal may be kids who have a hypersensitivity to at least some

> > antigens generated by yeast.

> >

> > D. A parallel is found in allergies to cats and peanuts. Whereas most

> > individuals are fine while eating peanuts in the presence of cats,

some

> > individuals know that the presence of either, even in trace amounts,

> > causes adverse reactions.

> >

> > E. Perhaps the low-yeast-on-CDSA kids who improve via antifungals are

> > kids whose hypersensitivity reactions to yeast (see B above) are kids

> > for whom the antifungal is (temporarily) drastically reducing the

level

> > of yeast-derived antigens, thereby minimizing or transiently

eliminating

> > source of the child's yeast-hypersensitivity reaction.

> >

> > This model is very different from the alternative model whereby the

> > child who improves via antifungals despite " no " yeast via CDSA is said

> > to have yeast colonization despite the negative lab findings.

> >

> > Parental observations about regressions during allergy seasons would

be

> > informative.

> >

> >

> >

> >

> >

> >

> >

> >

> >

> > Many frequently asked questions and answers can be found at

> <http://www.autism-rxguidebook.com/forums>

> >

[Guest guest]

Hi, Abbie -

Sorry so late - my household still hasn't recovered from my absence at the

DAN conference!

My son's allergy regimen is detailed below (Nasacort AQ, Nasalcrom, Intal

nebs, prn Xopenex nebs, Singulair, Quercetin and Gastrochrom). He is on a

yeast-free diet (and all the other F's). We started the Nasalcrom (OTC) and

Intal nebs (scrip) when the doc thought that his behavioral blip was due to

molds, with great improvement in both asthma/allergies and behaviors. Our

next step would be to have him tested for airborne allergens and molds - you

can test for 16 types of molds using PND methods

(Provocation-Neutralization-Desensitization), which I don't understand very

well but is detailed in Doris Rapp's book " Is This Your Child? " and probably

elsewhere. Our allergist/DAN doc is Dr. Layton in Towson, MD. My son has not

yet had this testing (it's pricey). My daughter (15 years old, severe asthma

and allergies, ADHD/ODD/Asperger'y) had the testing done last summer after 5

1/2 years of traditional immunotherapy (which contained molds) and daily

asthma management, with improvement but still daily allergy symptoms and

asthma flares several times a year. She tested positive to 15 of the 16

molds, and most of the airborne allergens. She started sublingual

immunotherapy daily based on the testing results using PND, and her asthma

and allergies have never been so well controlled - she is a different child.

We were able to stop her allergy shots. She had a symptom flare at the same

time as he did (March), and we upped her drops to twice a day, and her

symptoms went right away. (Every other year at this time, she ended up on

antibiotics and oral steroids and maxed-out asthma management for

pneumonis/sinusitis/asthma issues). We haven't done the boy yet, because he

hasn't seemed so bad, and for financial issues, but we're heading in that

direction. I also scrub their bathroom frequently, and we live in a dry

house. He was born in SE Louisiana, with a lagoon (complete with alligator,

LOL) in the backyard, so he has had plenty of exposure to mold. I don't

think that mold becomes yeast, but I wonder if it cross-reacts or sensitizes

you to yeast. Maybe it's just that my kids are so very IgE-mediated

allergic.

I also think that is " allergic " to yeast. I know that he has IgG to

both Brewer's yeast and baker's yeast, and he didn't tolerate Saccharomyces

boullardi (thanks to Anagrammy for teaching me about the connection!). He

has never been tested for allergy to Candida - is there such a thing? I have

not tried him on Aquaflora because of my concerns about possible yeast

allergy. Anybody have any thoughts?

Kathy

yeast not excessive, but child responds to

> antifungals; regressions during pollen seasons

>

>

> > During a conversation at the recent DAN! in Mclean, Va, Jim

Neubrander,

> > M.D.,

> > offered a fascinating model for understanding why some autistic kids

> > show no elevated yeast via CDSA but show positive response to

antifungals.

> >

> > Here is my rendition of Jim's hypothetical offering:

> >

> > A. Virtually everyone has yeast, and most healthy people would test

low

> > for Candida species on a CDSA.

> >

> > B. Jim and other docs have reported that some autistic kids regress

> > (mildly?) during times of pollen, an observation that links immune

> > reactions to regressions.

> >

> > C. Jim offered that perhaps the low-yeast-on-CDSA kids who improve via

> > an antifungal may be kids who have a hypersensitivity to at least some

> > antigens generated by yeast.

> >

> > D. A parallel is found in allergies to cats and peanuts. Whereas most

> > individuals are fine while eating peanuts in the presence of cats,

some

> > individuals know that the presence of either, even in trace amounts,

> > causes adverse reactions.

> >

> > E. Perhaps the low-yeast-on-CDSA kids who improve via antifungals are

> > kids whose hypersensitivity reactions to yeast (see B above) are kids

> > for whom the antifungal is (temporarily) drastically reducing the

level

> > of yeast-derived antigens, thereby minimizing or transiently

eliminating

> > source of the child's yeast-hypersensitivity reaction.

> >

> > This model is very different from the alternative model whereby the

> > child who improves via antifungals despite " no " yeast via CDSA is said

> > to have yeast colonization despite the negative lab findings.

> >

> > Parental observations about regressions during allergy seasons would

be

> > informative.

> >

> >

> >

> >

> >

> >

> >

> >

> >

> > Many frequently asked questions and answers can be found at

> <http://www.autism-rxguidebook.com/forums>

> >

[Guest guest]

Abbie et al -

Dr. Layton just told me that his personal opinion is that the antifungals

treat molds as well as yeast, which is part of the improvement he sees.

Molds would not be seen on the CDSA. Maybe this is why some kids get better

on antifungals, even with a negative CDSA (except for microscopy)? Another

theory.

Kathy

yeast not excessive, but child responds to

> > antifungals; regressions during pollen seasons

> >

> >

> > > During a conversation at the recent DAN! in Mclean, Va, Jim

> Neubrander,

> > > M.D.,

> > > offered a fascinating model for understanding why some autistic

kids

> > > show no elevated yeast via CDSA but show positive response to

> antifungals.

> > >

> > > Here is my rendition of Jim's hypothetical offering:

> > >

> > > A. Virtually everyone has yeast, and most healthy people would

test

> low

> > > for Candida species on a CDSA.

> > >

> > > B. Jim and other docs have reported that some autistic kids

regress

> > > (mildly?) during times of pollen, an observation that links immune

> > > reactions to regressions.

> > >

> > > C. Jim offered that perhaps the low-yeast-on-CDSA kids who improve

via

> > > an antifungal may be kids who have a hypersensitivity to at least

some

> > > antigens generated by yeast.

> > >

> > > D. A parallel is found in allergies to cats and peanuts. Whereas

most

> > > individuals are fine while eating peanuts in the presence of cats,

> some

> > > individuals know that the presence of either, even in trace

amounts,

> > > causes adverse reactions.

> > >

> > > E. Perhaps the low-yeast-on-CDSA kids who improve via antifungals

are

> > > kids whose hypersensitivity reactions to yeast (see B above) are

kids

> > > for whom the antifungal is (temporarily) drastically reducing the

> level

> > > of yeast-derived antigens, thereby minimizing or transiently

> eliminating

> > > source of the child's yeast-hypersensitivity reaction.

> > >

> > > This model is very different from the alternative model whereby

the

> > > child who improves via antifungals despite " no " yeast via CDSA is

said

> > > to have yeast colonization despite the negative lab findings.

> > >

> > > Parental observations about regressions during allergy seasons

would

> be

> > > informative.

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > > Many frequently asked questions and answers can be found at

> > <http://www.autism-rxguidebook.com/forums>

> > >

[Guest guest]

Kathy,

This is where Dr Layton's opinion really is a bonus because of his many

years as a pediatrician that treats allergies and a DAN doc also. He may

be on to something here because I suspect a lot of kids are in this

category of no issues on labs but yet they see improvement on

anti-fungals. We noticed this with JW. After the flagyl and diflucan

made the labs normal, we still saw improvement each time he went on

anti-fungals. Maybe some of the kids are hyper sensitive to molds. This

is one plausible explanation and I'm sure there are others. In addition,

I noticed all of the parents that briefed recovery stories at DAN had

anti-fungals as one of their top treatments. I think the key is finding

out which anti-fungal (and dose) does best for each child. L

PS We see Dr Layton next Tues and I will talk more to him about it.

Re: airborne molds (response to Abbie - long)

Abbie et al -

Dr. Layton just told me that his personal opinion is that the

antifungals

treat molds as well as yeast, which is part of the improvement he sees.

Molds would not be seen on the CDSA. Maybe this is why some kids get

better

on antifungals, even with a negative CDSA (except for microscopy)?

Another

theory.

Kathy

yeast not excessive, but child responds

to

> > antifungals; regressions during pollen seasons

> >

> >

> > > During a conversation at the recent DAN! in Mclean, Va, Jim

> Neubrander,

> > > M.D.,

> > > offered a fascinating model for understanding why some

autistic

kids

> > > show no elevated yeast via CDSA but show positive response to

> antifungals.

> > >

> > > Here is my rendition of Jim's hypothetical offering:

> > >

> > > A. Virtually everyone has yeast, and most healthy people would

test

> low

> > > for Candida species on a CDSA.

> > >

> > > B. Jim and other docs have reported that some autistic kids

regress

> > > (mildly?) during times of pollen, an observation that links

immune

> > > reactions to regressions.

> > >

> > > C. Jim offered that perhaps the low-yeast-on-CDSA kids who

improve

via

> > > an antifungal may be kids who have a hypersensitivity to at

least

some

> > > antigens generated by yeast.

> > >

> > > D. A parallel is found in allergies to cats and peanuts.

Whereas

most

> > > individuals are fine while eating peanuts in the presence of

cats,

> some

> > > individuals know that the presence of either, even in trace

amounts,

> > > causes adverse reactions.

> > >

> > > E. Perhaps the low-yeast-on-CDSA kids who improve via

antifungals

are

> > > kids whose hypersensitivity reactions to yeast (see B above)

are

kids

> > > for whom the antifungal is (temporarily) drastically reducing

the

> level

> > > of yeast-derived antigens, thereby minimizing or transiently

> eliminating

> > > source of the child's yeast-hypersensitivity reaction.

> > >

> > > This model is very different from the alternative model

whereby

the

> > > child who improves via antifungals despite " no " yeast via CDSA

is

said

> > > to have yeast colonization despite the negative lab findings.

> > >

> > > Parental observations about regressions during allergy seasons

would

> be

> > > informative.

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > > Many frequently asked questions and answers can be found at

> > <http://www.autism-rxguidebook.com/forums>

> > >

[Guest guest]

After discussion on the list about

antifungals/antiyeast/antibacterial meds, I was wondering if someone

would list in order the ones that our children currently seem to

respond best to. We saw gains with Flagyl and Diflucan. I remember

in CSB that these were both recommendations.

Thank you,

Theresa, SA

> Kathy,

>

> This is where Dr Layton's opinion really is a bonus because of his

many

> years as a pediatrician that treats allergies and a DAN doc also.

He may

> be on to something here because I suspect a lot of kids are in this

> category of no issues on labs but yet they see improvement on

> anti-fungals. We noticed this with JW. After the flagyl and

diflucan

> made the labs normal, we still saw improvement each time he went on

> anti-fungals. Maybe some of the kids are hyper sensitive to molds.

This

> is one plausible explanation and I'm sure there are others. In

addition,

> I noticed all of the parents that briefed recovery stories at DAN

had

> anti-fungals as one of their top treatments. I think the key is

finding

> out which anti-fungal (and dose) does best for each child. L

> PS We see Dr Layton next Tues and I will talk more to him about it.