Folate synthesized by bacteria in the human upper small intestine is assimilated by the host

January 1, 2004

I know I am coming in to this thread late, but I am about 2 weeks

behind in catching up on e-mails. I have found this thread about

elevated folate and B-12 levels very interesting. Thank you

for posting the research that it may be the bad bacteria in the gut

that is producing high folate and B-12 levels. My son's OATs

continually come back with elevated markers for anaerobic bacteria.

And he has sky high serum B-12 and folate. We have tried injectible

methyl B-12 aand also folinic acid with little to no positive

impact. But recently Dr Bradstreet started my son on a 3 month

course of Flagyl (every other week) and antigfunglas (sporonox

alternating weekly with diflucan). Wow, what a difference Flagyl has

been making. Within a few days of Flagyl, my son was more lucid, had

better receptive language, and better epxressive language, more

complex language (for example, he picked up my cup of hot tea, took a

sip, and said " Look mom, a tea mustache! " ). This is truly amazing

for him. The flagyl aslo seems to be regulating his bowel movements,

from going every 3-4 days to going nearly every day. We are now on a

off flagyl week (Dr B prescribed it every other week), and I am

noticing the improvements going away very fast. As a result I cannot

wait to start him up again tomorrow. The antifungals don't seem to

be the impacting agent, but the flagyl does. I wonder if he can be

onthis long term. Have others noted such a gresat response to

flagyl? Maybe you are right about the bacterial byprodcuts

creating a nboise level int he brain, where it is hard for the kids

to concentrate. My son was diagnoised with marked colitis and LNH of

the termoinal ilieum by Dr Krigsman last fall. He is definietly a

severe gut kid. The SCD helped get formed stools, but wow the flagyl

is really rocking. Will keep you posted. WOuld love to know of

anyone else's experience. Maybe elevated B-12 and folate should mean

a trial of Flagyl for our kids, especailly with OAT markers for

anerobic bacteria. Thoughts?

Beth

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