Guest guest Posted October 13, 2004 Report Share Posted October 13, 2004 The dose and the host (i.e., susceptibility factors) make the poison. May be HLA polymorphisms in chronic, mold-induced illness. **** These comments are my own and don't reflect Agency policy**** H Hudnell, PhD Neurotoxicologist US Environmental Protection Agency MD-B105-05 Research Triangle Park, NC 27711 Ph.: ; Fx.: *** The absence of evidence of harm is not the same thing as evidence of the absence of harm, and vice versa - Do the research! *** Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 13, 2004 Report Share Posted October 13, 2004 > The dose and the host (i.e., susceptibility factors) make the poison. > May be HLA polymorphisms in chronic, mold-induced illness. > H Hudnell, PhD Indeed! And if the susceptibility factors manifest as mold illness in someone who had no presumed greater exposure than the person sitting next to them who has no complaints whatsoever, then it is the HLA-DR that makes the " benign " exposure toxic, and not the dose that proved harmless to others. Come on! I know for a fact that there are others on this board who are aware of this! 'Fess up and speak! - the Stachysterian Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 14, 2004 Report Share Posted October 14, 2004 Define "dose", therein lies the difference. Stevan -----Original Message-----From: erik_johnson_96140 Sent: Thursday, October 14, 2004 12:58 AMTo: iequality Subject: Re: dose-response functions> The dose and the host (i.e., susceptibility factors) make the poison. > May be HLA polymorphisms in chronic, mold-induced illness.> H Hudnell, PhDIndeed!And if the susceptibility factors manifest as mold illness in someone who had no presumed greater exposure than the person sitting next to them who has no complaints whatsoever, then it is the HLA-DR that makes the "benign" exposure toxic, and not the dose that proved harmless to others.Come on! I know for a fact that there are others on this board who are aware of this!'Fess up and speak! - the StachysterianFAIR USE NOTICE:This site contains copyrighted material the use of which has not always been specifically authorized by the copyright owner. We are making such material available in our efforts to advance understanding of environmental, political, human rights, economic, democracy, scientific, and social justice issues, etc. We believe this constitutes a 'fair use' of any such copyrighted material as provided for in section 107 of the US Copyright Law. In accordance with Title 17 U.S.C. Section 107, the material on this site is distributed without profit to those who have expressed a prior interest in receiving the included information for research and educational purposes. For more information go to: http://www.law.cornell.edu/uscode/17/107.shtml. If you wish to use copyrighted material from this site for purposes of your own that go beyond 'fair use', you must obtain permission from the copyright owner. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 14, 2004 Report Share Posted October 14, 2004 Thoughts on dose Chronic exposure to the indoor environment of buildings with evidence of water intrusion and microbial amplification is associated with multiple-system illness in Dr. Shoemaker's article that is in press at Neurotoxicology & Teratology (Jan/Feb'05 issue). A complex mixture of fungi, mycotoxins, bacteria, endotoxins, antigens, and microbial-produced VOCs is inhaled in that environment. The constitutiants and concentrations in the mixture change over time. Many toxic components are likely not yet identified. Therefore, the " dose " is undefinable. Ken **** These comments are my own and don't reflect Agency policy**** H Hudnell, PhD Neurotoxicologist US Environmental Protection Agency MD-B105-05 Research Triangle Park, NC 27711 Ph.: ; Fx.: *** The absence of evidence of harm is not the same thing as evidence of the absence of harm, and vice versa - Do the research! *** Stevan Pierce <stevan.pierce@atcasso To: iequality ciates.com> cc: Subject: RE: Re: dose-response functions 10/14/2004 11:44 AM Please respond to iequality Define " dose " , therein lies the difference. Stevan Re: dose-response functions > The dose and the host (i.e., susceptibility factors) make the poison. > May be HLA polymorphisms in chronic, mold-induced illness. > H Hudnell, PhD Indeed! And if the susceptibility factors manifest as mold illness in someone who had no presumed greater exposure than the person sitting next to them who has no complaints whatsoever, then it is the HLA-DR that makes the " benign " exposure toxic, and not the dose that proved harmless to others. Come on! I know for a fact that there are others on this board who are aware of this! 'Fess up and speak! - the Stachysterian FAIR USE NOTICE: This site contains copyrighted material the use of which has not always been specifically authorized by the copyright owner. We are making such material available in our efforts to advance understanding of environmental, political, human rights, economic, democracy, scientific, and social justice issues, etc. We believe this constitutes a 'fair use' of any such copyrighted material as provided for in section 107 of the US Copyright Law. In accordance with Title 17 U.S.C. Section 107, the material on this site is distributed without profit to those who have expressed a prior interest in receiving the included information for research and educational purposes. For more information go to: http://www.law.cornell.edu/uscode/17/107.shtml. If you wish to use copyrighted material from this site for purposes of your own that go beyond 'fair use', you must obtain permission from the copyright owner. FAIR USE NOTICE: This site contains copyrighted material the use of which has not always been specifically authorized by the copyright owner. We are making such material available in our efforts to advance understanding of environmental, political, human rights, economic, democracy, scientific, and social justice issues, etc. We believe this constitutes a 'fair use' of any such copyrighted material as provided for in section 107 of the US Copyright Law. In accordance with Title 17 U.S.C. Section 107, the material on this site is distributed without profit to those who have expressed a prior interest in receiving the included information for research and educational purposes. For more information go to: http://www.law.cornell.edu/uscode/17/107.shtml. If you wish to use copyrighted material from this site for purposes of your own that go beyond 'fair use', you must obtain permission from the copyright owner. Quote Link to comment Share on other sites More sharing options...
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