Re: Hiv and autism 2 - HIV and Borrelia/lyme

March 18, 2009

Very interesting. We all understand that lyme is difficult to detect, yet take

if for granted that we know we don't have HIV as we have been tested. I have

long felt that we have some sort of AIDS to be as ill as we are, although I

assumed it was caused by something other than HIV. Perhaps it is not?

Caryn

March 18, 2009

and we don’t know if there is another virus, similar to hiv (but not as deadly/obvious) out there, that we are not testing for.

btw hsv6 behaves in very similar ways to hiv, in many respects (disabling the immune system, neurotoxicity etc), and that one is terribly difficult to detect by standard tests.

got knows how many hiv-like viruses other there, helped greatly by emf, polution and vaccinations...

Very interesting. We all understand that lyme is difficult to detect, yet take if for granted that we know we don't have HIV as we have been tested. I have long felt that we have some sort of AIDS to be as ill as we are, although I assumed it was caused by something other than HIV. Perhaps it is not?

Caryn

March 18, 2009

I find it interesting that children with HIV (pleomorphic virus), regress into

autism symptoms at 1.5 to 2 years of age. This is of course similar to what we

are seeing in the autism epidemic or rather pandemic. So basically, autism is a

crash of the immune system, caused by either pleomorphic pathogens (Lyme,

syphilis, Bartonella and mycoplasma fermentans are pleomorphic), too many

pathogens in general, or toxins or both. Now, how to make that sound

scientific?

Love and prayers,

Heidi N

>

> Br J Dermatol. 1997 Sep;137(3):437-9.

>

> Atypical Lyme borreliosis in an HIV-infected man.

>

> Cordoliani F, Vignon-Pennamen MD, Assous MV, Vabres P, Dronne P, Rybojad

> M, Morel P. Service de Dermatologie, HÃ´pital Saint-Louis, Paris, France.

>

> We report the fourth case of Lyme borreliosis in a man infected with

> human immunodeficiency virus (HIV). The erythema chronicum migrans was

> persistent, overlapping with meningoradiculitis. Repeated immunofluorescence

> tests for Borrelia burgdorferi sensu lato remained negative in both sera and

> cerebrospinal fluid (CSF), the enzyme-linked immunosorbent assay was weakly

> positive in serum and CSF and a Western blot was positive. The skin

> infiltrate was composed mostly of T lymphocytes with a CD4/CD8 ratio of 0.5.

> The course of the disease was favourable after treatment with intravenous

> ceftriaxone. Further studies are necessary to evaluate whether HIV infection

> influences, as does syphilis, the course and response to treatment of Lyme

> borreliosis. Serological tests are insufficiently sensitive and the Western

> blot assay is necessary to confirm Lyme disease in HIV-positive

> patients.PMID: 9349345

>

> Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004 Sep;98(3):321-3.

>

> Fusospirochetosis causing necrotic oral ulcers in patients with HIV

> infection.

>

> Salama C, Finch D, Bottone EJ. Division of Infectious Diseases,

> Elmhurst Hopsital Center, NY, USA. csalama@...

>

> Under certain permissive circumstances, normally occurring fusiform

> bacteria and Borrelia spirochetes can result in a symbiotic overgrowth that

> leads to necrotic oral ulcers (stomatitis), gingivitis, and periodontitis.

> These lesions are collectively known as oral fusospirochetosis and may be

> under-appreciated in patients with HIV infection and AIDS. Fusospirochetal

> oral ulcers in patients with HIV are often large, necrotic, and malodorous;

> they respond completely to penicillin. We report 3 patients with HIV

> infection and fusospirochetal ulcerative stomatitis and review the clinical

> presentation, microbiologic diagnosis, potential pathogenesis, and treatment

> of these lesions. PMID: 15356470

>

> Niger J Med. 2006 Oct-Dec;15(4):455-6.

>

> Spirochaetemia in a HIV positive patient.

>

> Okwori EE.

> BACKGROUND: Borreliosis, caused by Borrelia recurrentis and several other

> Borrelia species is not a commonly reported case in our environment, but the

> search for the cause of recurrent pyrexia in this patient made it possible

> to discover the spirochete as the cause of the disease. METHOD: A 38 year

> old married HIV positive woman presented with recurrent fever in a private

> clinic. Six thin smears were made out of the patient serum and dried in the

> air. Three slides each were stained with 0.12% Leishman and 20% Giemsa

> stains and examined under the light microscope. RESULT: Three of the Giemsa

> slides were positive for spirochetes (4-5 spirals), which were constituents

> with Borrelia species. The patient responded very well to tetracycline and

> serum became negative for the organism after ten days of treatment.

> CONCLUSION: Borrelia was discovered to be the cause of the recurrent pyrexia

> in this patient who responded very well to tetracycline. Borrelia should be

> looked for in cases of pyrexia of unknown origin PMID: 17111740

>

> Med Clin (Barc). 1993 Jul 3;101(6):207-9.

>

> [infection by Borrelia burgdorferi in patients with the human

> immunodeficiency virus. A diagnostic problem]

>

> [Article in Spanish] Oteo Revuelta JA, ElÃas Calvo C, MartÃnez de Artola

> V, PÃ©rez Surribas D. Servicio de Medicina Interna, Hospital de La Rioja,

> LogroÃ±o.

>

> BACKGROUND: Given that Lyme's disease and HIV infection may present with

> similar clinical symptoms and that the serologic tests for the determination

> of antibodies against Borrelia burgdorferi present frequent false positives,

> the presence of antibodies against B. burgdorferi in patients with HIV in

> different evolutive stages was studied. METHODS: Antibodies against B.

> burgdorferi were determined by IFI and ELISA in a serum sample of 72

> individuals with HIV. Western blot (WB) against B. burgdorferi was performed

> in the sera which were positive by one method or the other. The presence of

> antiphospholipid antibodies was also studied. RESULTS: A total of 24 sera

> (33%) were positive by IFI and/or ELISA. Twenty-one (29%) by IFI and 7 (10%)

> by ELISA (chi 2; p = 0.006). Four (5.5%) were positive by both methods. Only

> one of the sera was positive by IFI, ELISA and WB. No statistical relation

> was found upon comparison of the positive results against B. burgdorferi

> with the different evolutive stages of HIV infection or with the presence of

> antiphospholipid antibodies. CONCLUSIONS: The high prevalence of false

> positive serology to B. burgdorferi in the collective of patients with the

> human immunodeficiency virus infection together with the possibility of

> presenting similar clinical manifestations has led to extreme prudence in

> the diagnosis of infection by B. burgdorferi in patients with HIV infection.

> PMID: 8332020

>

> Infection. 2006 Apr;34(2):100-2.

>

> Neuroborreliosis in an HIV-1 positive patient.

>

> CernÃ½ R, Machala L, Bojar M, Rozsypal H, PÃcha D. Department of

> Neurology, University in Prague, 2nd Faculty of Medicine, V Uvalu

> 84, 15006 Praha 5, Czech Republic. rudolf.cerny@...

>

> Simultaneous co-infections of Borrelia burgdorferi sensu lato and HIV-1

> are rare events, with only six published cases. A case of acute

> neuroborreliosis with facial palsy, meningoradiculitis (Bannwarth's

> syndrome) in an HIV-1 positive individual is described. Diagnosis was

> confirmed by Western immunoblot analysis of serum and CSF and by proof of

> intrathecal production of antibodies against B. garinii. The patient was

> successfully treated with cefotaxime. In all published HIV+ cases, the

> course of borreliosis did not differ from that of the HIV negative

> population and the prognosis in properly treated patients was good.

> Publication Types:PMID: 16703302

>

> Hautarzt. 1989 Aug;40(8):504-9.

>

> [borrelia burgdorferi-induced pseudolymphoma with pathogen cultivation in

> an HIV-1 positive patient]

>

> [Article in German] Bratzke B, Stadler R, Gollnick H, Rolfs A,

> HÃ¶ffken G, Preac-Mursic V, Wilske B, Schaart F, Orfanos CE.

> UniversitÃ¤ts-Hautklinik und Poliklinik, Freien UniversitÃ¤t Berlin.

>

> Cutaneous symptoms and skin diseases are common findings in almost all

> HIV-1-positive patients. In many cases the clinical presentation and course

> of the skin diseases are atypical, and occasionally the development of the

> appropriate circulating antibodies is lacking or impaired. In this report we

> present a patient seen in our multidisciplinary outpatient clinic for HIV

> patients. This patient had a Borrelia burgdorferi infection with an unusual

> course. The acute inflammatory phase of the arthropod reaction was

> maintained over a period of 9 months with development into pseudolymphoma

> showing unusual cytological characteristics. Immunohistological evaluation

> revealed an almost complete lack of T-helper and Langerhans cells, but an

> increased number of activated cytotoxic cells with class II antigen

> expression. A marked serological response was observed on IgG-ELISA and in

> the IgG-immunofluorescence test. Borrelia burgdorferi was cultured in vitro

> from a skin biopsy of the involved area. To our knowledge this is the first

> reported case of skin borreliosis in an HIV-1-positive patient ID: 2676912

>

> Enferm Infecc Microbiol Clin. 1991 Jun-Jul;9(6):335-8.

>

> [serologic diagnosis of Lyme disease. A pending problem]

>

> [Article in Spanish] Guerrero A, Quereda C, Escudero R, Cobo J,

> Morcillo R, MartÃ-Belda P. SecciÃ³n de Enfermedades Infecciosas, Hospital

> RamÃ³n y Cajal, Universidad de AlcalÃ¡ de Henares, Madrid.

>

> We analyze the experience in serologic diagnosis of Lyme's borreliosis.

> From a total of 551 patients studied from 1987 to 1989, we further evaluate

> 80 cases with erythema chronicum migrans or a clinical diagnosis of Lyme's

> disease and positive serological tests. The techniques used were IFI, ELISA1

> (Whittaker Bioproducts) and ELISA2 (MarDx Diagnostics). Serological tests

> results were evaluated in relation to clinical data. Five cases were

> excluded because of no-specific symptoms. There were 20 false-positive

> results, mainly due to other infections (HIV infection, tuberculosis,

> Mediterranean spotted fever and syphilis). Fifty-five patients were

> considered clinically of having Lyme's disease. IFI test was positive in

> 81.8% of all the 55 cases, ELISA2 in 58.4% of 53 cases tested and ELISA1 in

> 23% of 43 cases tested. Correlation between IFI and ELISA2 positive test was

> seen in 45% of cases. Specificity of all tests was higher than 97%. The

> study shows that sensitivity for all three techniques used was not optimal,

> and also there are some differences in their results. However, specificity

> was adequate. PMID: 1932240

>

March 18, 2009

I saw a study on rats showing that prenatal pathogen insults on the developing brain leads to changes in their gene expression, which only became apparent once they got a bit older. So that is one way of explaining.

the other is reactivation of latent viruses etc through vaccination during that period. (mind you, our son was early onset, but very mild, and regressed slowly after the first birthday even though he wasn’t vaccinated...)

natasa x

I find it interesting that children with HIV (pleomorphic virus), regress into autism symptoms at 1.5 to 2 years of age. This is of course similar to what we are seeing in the autism epidemic or rather pandemic. So basically, autism is a crash of the immune system, caused by either pleomorphic pathogens (Lyme, syphilis, Bartonella and mycoplasma fermentans are pleomorphic), too many pathogens in general, or toxins or both. Now, how to make that sound scientific?