Re: Another DMSO and Mast Cell Cancer Question ;-)

March 8, 2004

I would start out with very dilute DMSO, 1-5% and 10 ppm CS. Then I

would observe the reaction for perhaps a week, before increasing to

5-10%. Going stepwise will do two things. It will allow you to detect

any problems at a low level of exposure. And it will allow the histamine

stores to be depleted slowly, which is what happens with normal DMSO use

in the same spot.

If I did detect any untoward reaction I would look for a vet who would

instruct me in the injection of the tumor itself with CS directly. I

might even go to a high ppm (500) protien bound CS for a short period of

time.

Garnet

> I was re-reading through the archives and found this reference to

> histamine release:

>

> > It can sting and causes a histamine release in topical use. Hence the

> > warming feeling you get with topical application. Most people dilute it

> > to 50% for topical use. Best to skin test a small area. Some can use it

> > full stregnth with no problem. I personally start out with 10% and work

> > up when I am experimenting.

>

> Since mast cell tumors are LOADED with histamines (which is what causes

> the tumor swelling) might DMSO use be contraindicated? Basically I am

> looking for a vehicle to transport artemisinin through the skin into a

> large mast cell tumor on my dog's leg. I can't use aloe vera since it

> can mess with insulin levels and my Mojo is also diabetic. Perhaps emu

> oil as the vehicle?

>

> Does anyone have any ideas or suggestions?

>

> Thanks!

>

> Dee and Mojo

>

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