Re: BS intolerance syndrome

[Guest guest]

Dear

Been there, done that. When I weas your age I had a profound daytime sleepiness problem, seemed to be a blood sugar issue. , Worth reading about. Now I'm over the hill, so to speak I have just found the mostr marvellous treatment for "Bullshit Intollerance Syndrome" 25 mcg Clonidine b.i.d.. Life is improving markedly. I am now completely unconcerned with the fate of the world and am happily getting on with my own personal endeavours.

Have a read of Jay Goldstein's "Tuning the brain " for some fairly succinct comment on certain brain receptor stuff and heaps of less succint material as well.

Personally I found dexamphetamine of less use than a cup of coffee and not neary as good as a social lubricant. Ritalin was marvellous until I found I was intollerant of beta casein A1, gave up milk and Ritalin as well. I found that non-restorative sleep had more effect on daytime sleepiness in later years. Getting effective sleep by use of several GABA agonists in fact gave better daytime function in large measure.

Regards

Windsor

[infections] BS intolerance syndrome

Yeah I have clear cardiac and CNS manifestations of that... actually I was born under that star but I generally keep it under wraps.I find curiosity is the truly strong glue for getting your stuff together in the long run. Everything I hunted over the last 2 years is hardwired, even if it did take stupidly long to get certain keystones in place. Biochem/cell/molbio GREs are right on target. I've definitely learned tons from classes - just not quite as much as from private study and lab research mentorship.O-chem's the one subject I did strictly scholastically, and gritted for two A-minuses by scrawling every law and reaction mech 25 times in a notebook. And I barely remember the easy stuff, despite even having a superb lecturer, my best yet. (He kept it *way* linear, by using an overhead projector with hand-drawn transparencies that he altered or elaborated as he lectured - not powerpoint which IMO is usually a didactic white elephant piece of crap.) If I could liven up a lil I'd just give Academus his pound of flesh without a wince. Its hard to do when your waking day is (not counting drowsiness troughs during the day) maybe 3 hours short of the mean - a stiff %difference in disposable time.

[Guest guest]

Thanks. I guess I'm not too certain that amphetamine or any

catecholaminergics will work well as a chronic treatment for me.

I've looked at a few anecdotes/claims. Re both ADD and somnolence.

Some people have continuing benefit. Some have loss of benefit. I

guess only formal data can show how many of the former eventually

become the latter.

Steve claims:

" They [ADD] require increased doses just from tolerance. The mean

time to dose increase in the blinded studies is a few months, and it

keeps going up the longer they measure it. "

I'd want to make sure he's right about that. Even if he is, of

course, there's also the question of whether a few lucky people might

build no tolerance even over many years. If so, it may or may not be

worth any risks involved in trying to find out if you are one of

those people.

So, how long did you take ritalin, and did you have tolerance?

Can you not get it free of milk?

The Steve quote may be seen here:

http://yarchive.net/med/add.html

He's alot of fun intellectually.

>

> Dear

> Been there, done that. When I weas your age I had a profound

daytime sleepiness problem, seemed to be a blood sugar issue. , Worth

reading about. Now I'm over the hill, so to speak I have just found

the mostr marvellous treatment for " Bullshit Intollerance Syndrome "

25 mcg Clonidine b.i.d.. Life is improving markedly. I am now

completely unconcerned with the fate of the world and am happily

getting on with my own personal endeavours.

> Have a read of Jay Goldstein's " Tuning the brain " for some fairly

succinct comment on certain brain receptor stuff and heaps of less

succint material as well.

> Personally I found dexamphetamine of less use than a cup of coffee

and not neary as good as a social lubricant. Ritalin was marvellous

until I found I was intollerant of beta casein A1, gave up milk and

Ritalin as well. I found that non-restorative sleep had more effect

on daytime sleepiness in later years. Getting effective sleep by use

of several GABA agonists in fact gave better daytime function in

large measure.

> Regards

> Windsor

[Guest guest]

Dear

Took Ritalin for a couple of years. I didn't experience tolerance in any way and don't believe that in 10 years or more, have I ever seen anyone who has. Big problem with ADHD and Ritalin (or dex) is that Ducs won't , as a rule, titrate dosage. Unless a clear cost/ benefit relationship is established then lots of wild claims can be subsequently made. Titration should also include the alternatives. Here in Aus there is a generic Methylphenidate which has a very different effect to Ritalin in some persons.

In ADHD, about 70% respond beneficially to Ritalin, about 70% to Dexamphetamine with a great deal of overlap. About 10 % do not respond beneficially to either (I think I am probably one of those) Among the overlap, some do better on Ritalin, some on Dex. I am not sure what the response is to the generic Methylphenidate but I know of one case where the patient was non-responsive to both Dex and Ritalin but responded well to the generic.

The issue with milk is not as a component of the medication but in ther fact that beta casein A1 in milk has a digestive peptide fragment Casomorphin ,which in some people, is strongly neuroactive( or even neurotoxic). Ritalin protected me to an extent from that. No milk, no need for Ritalin. In Aus we can buy A2 milk which is guaranteed free of beta casein A1, I can drink it with impunity. A1 makes me very socially unacceptable.

Regards

Windsor

[infections] Re: BS intolerance syndrome

Thanks. I guess I'm not too certain that amphetamine or any catecholaminergics will work well as a chronic treatment for me.I've looked at a few anecdotes/claims. Re both ADD and somnolence. Some people have continuing benefit. Some have loss of benefit. I guess only formal data can show how many of the former eventually become the latter. Steve claims:"They [ADD] require increased doses just from tolerance. The mean time to dose increase in the blinded studies is a few months, and it keeps going up the longer they measure it."I'd want to make sure he's right about that. Even if he is, of course, there's also the question of whether a few lucky people might build no tolerance even over many years. If so, it may or may not be worth any risks involved in trying to find out if you are one of those people. So, how long did you take ritalin, and did you have tolerance? Can you not get it free of milk? The Steve quote may be seen here:http://yarchive.net/med/add.htmlHe's alot of fun intellectually. >> Dear > Been there, done that. When I weas your age I had a profound daytime sleepiness problem, seemed to be a blood sugar issue. , Worth reading about. Now I'm over the hill, so to speak I have just found the mostr marvellous treatment for "Bullshit Intollerance Syndrome" 25 mcg Clonidine b.i.d.. Life is improving markedly. I am now completely unconcerned with the fate of the world and am happily getting on with my own personal endeavours.> Have a read of Jay Goldstein's "Tuning the brain " for some fairly succinct comment on certain brain receptor stuff and heaps of less succint material as well.> Personally I found dexamphetamine of less use than a cup of coffee and not neary as good as a social lubricant. Ritalin was marvellous until I found I was intollerant of beta casein A1, gave up milk and Ritalin as well. I found that non-restorative sleep had more effect on daytime sleepiness in later years. Getting effective sleep by use of several GABA agonists in fact gave better daytime function in large measure.> Regards> Windsor