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Dear Dr. Mirkin: How common is muscle pain from cholesterol- lowering

drugs?

Some patients with high cholesterol levels are afraid to take

statins because off fear of developing side effects such as muscle

pain. A study from Scripps Mercy Hospital in San Diego reviews the

latest data on side effects of statins (The American Journal of

Medicine, May 2006). This review found that statin- induced muscle

damage is more common in Asians, people who exercise, have had recent

surgery, have kidney, liver or thyroid disease, or have high

triglycerides. The incidence of muscle pain and damage from statins

is extremely low in non- exercisers, three to ten percent in those

who exercise, and very high in competitive athletes. Most athletes

refuse to take statin drugs because they train by taking a hard

workout that damages their muscles. Then they must take easy

workouts until the soreness disappears and muscles heal. When statins

prevent this muscle healing, the athlete must train at reduced

intensity for a much longer period of time. Brand names of statins

include:

Altoprev, Crestor, Lipitor, Mevacor, Pravachol and Zocor.

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