Magnesium and Herxing

[Guest guest]

This is not for the purpose of arguing, because honestly I don't

even begin to understand what all is here that I am going to post.

All I know is the experience myself and others have had regarding

Magnesium and herxing. You guys can take it for what it's worth, and

just as something for you more scientific minded to " think " about.

There is someone on Lynenet named Marnie, some of you likely know

her. Her specialty is Magnesium. She literally has written the book

over there on Mag, and has studied this subject up one side and back

down the other. Hundreds of hours invested into Magnesium research

as she believes that this is a MAJOR key to regaining health. She

has tons of documented evidence supporting what she says.

So, I thought, I would go ask Marnie, if she felt it was " possible "

to herx on Mag....and " yes " she did think it was possible, but she

didn't really say why.

So I asked her if she had scientific reason for thinking that, and

boy did she ever have reasons and the majority seems to be

documented. So here is her reply, cut and pasted and you can take a

look if your are interested.

================================================================

Documented...which I have done numerous times...Mg INactivates HMG

CoA reductase, stopping cholesterol (excess) production in the

liver. We KNOW...also documented...that Bb is following

the " cholesterol pathway " . It is stimulating the liver to pump out

excess cholesterol.

We KNOW Bb also follows the glycolysis pathway because Bb is " PFK

dependent " ...this is the rate limiting enzyme for glycolysis.

Insulin SPIKES activate this.

Mg INactivates PFK...as do some other things.

We also KNOW...for fact...that our OWN antibodies specifically

designed to fight Bb are damaged (fab portion) and restoring Mg

levels, restored the " health " of our own antibodies.

Documentation:

(1) The genetic analysis of Bb indicates it has a 60 kDa

pyrophosphate dependent PFK (phosphofructokinase) enzyme.

PMID: 12015149 (www.pubmed.com)

(2) The enzyme, PFK, is " rate limiting " for glycolysis (using

glycogen, not oxygen, to supply energy). And we know Bb is

anaerobic – does not need oxygen. It wants/needs sugar.

PMID: 10689623 (www.pubmed.com)

PMID: 1832860 (www.pubmed.com)

(3) PFK is INhibited by Mg-ATP (et al). (Most ATP is bound to Mg.).

Insulin ACTIVATES it.

http://www.geocities.com/doctor_uae/carbohydrates.htm

http://www.mcw.edu/student/mcwsa/files/biochem22.doc

http://www.eimb.relarn.ru/eimb/3nature.htm

www.apjohncancerinstitute.org/newsletter-old2.htm

http://www.lowcarbluxury.com/newsletter/lclnewsvol03-no04-pg2.html

(4) Bb follows the cholesterol/ mevalonate / isoprenoid pathway. It

has another enzyme: acetyl-CoA C-acetyltransferase. Cholesterol is

needed to form the myelin sheath, the insulation around our nerves.

In MS, this sheath is damaged.

(Rohmer 1999; Kim et al. 2000; Wilding et al. 2000a, . or

http://proteinscience.org/cgi/content/full/13/3/687

http://www.sbc.su.se/~anna/PhylProM/families_with_members_in_profile/

gi1652965.html

http://web.indstate.edu/thcme/mwking/cholesterol.html

http://adams.mgh.harvard.edu/Reeves/workingresearch2.htm

(5) Mg (and statin drugs) INactivate the enzyme 5-hydroxy-3-

methylglutaryl-coenzyme A reductase (HMG-CoA reductase) which then

reduces mevalonate, the first step in the cholesterol pathway.

http://www.lef.org/whatshot/2004_11.htm

Neurol India 2003;51:211-214

The above suggests that intracellular Mg levels play a critical role

in regaining control of the glycolysis and cholesterol pathways

which are impacted by this pathogen.

(6) Cancer doctors at a Romanian hospital found a very " significant "

drop in Mg levels early on in 2 lyme patients. By restoring their

magnesium levels, they were cured of lyme disease. Please note: this

was caught early.

http://www.coldcure.com/html/2003-mag-abstracts.pdf

(28) Bb locks onto a heparin receptor. It may be using fibrin to

cloak itself and thus avoid detection/destruction. Magnesium may

reduce insoluble fibrin.

http://www-heparin.rpi.edu/papers/PDFfiles_2000_present/CarbBased%

20Drug%20Discovery.pdf

http://64.233.167.104/search?

q=cache:Ay2HJ8b6iEQJ:medicine.plosjournals.org/perlserv/%3Frequest%

3Dread-response%26doi%

3D10.1371/journal.pmed.0020098+Magnesium+may+reduce+insoluble+

fibrin+levels+by+displacing+calcium+in+the+coagulation+process & hl=en

(29) Bb needs CHOLINE! It is taking this nutrient and others from us.

http://www.sbc.su.se/~anna/PhylProM/families_with_members_in_profile/

gi1652965.html

http://mic.sgmjournals.org/cgi/reprint/150/2/391

(30) Bb contains a PKC inhibitor. This is a protein kinase C

inhibitor. Protein kinase C inhibitors compete with Mg-ATP. PKC

inhibitors cause cell death. When the body is exposed to this

inhibitor, Mg is dumped quickly.

PMID: 8978084

http://www.biochemj.org/bj/351/0095/3510095.pdf

(32) Bb breaks down carbohydrates into toxic acetate and ethanol.

This reduces Ca and additional Mg.

http://www.bact.wisc.edu/Microtextbook/index.php?

name=Sections & req=viewarticle & artid=110 & page=1

www.emedicine.com/ped/topic2715.htm

(7) When Mg levels drop, this impacts the number and " health " of our

antibodies. Since the Western Blot test measures antibodies, this

may be why the testing is inaccurate (assuming it only measures

healthy antibodies). The antibody specific to Bb is damaged –

the " fab " portion.

PMID: 1093189 (www.pubmed.com)

PMID: 9125579 (www.pubmed.com)

(8) It takes Mg and Ca (calcium) to make completely HEALTHY

antibodies.

http://www.mdschoice.com/elements/elements/major_minerals/magnesium.h

tm

The above is all a part of my " Updated Nutshell " post which I have

to look at again...as I keep " updating " it...as even MORE pieces of

the puzzle fall into place.

There is so much happening in the body due to so many nutrients

taking a " hit " it is nearly impossible to say this->that cause this -

> that and that and that...

Choline, phosphorus,selenium, fructose, and zinc are some of the

nutrients Bb is taking from us.

The ONLY one to be careful with, IMO, is zinc.

High(ish) levels of Mg...SUSTAINED...can displace zinc...notice I

said DISPLACE...it it still present, but Bb has a hold of it.

We respond by dumping from storage a LOT of Mg...at the outset and

ongoing. We also use vitamin E to help protect (from ethanol...from

sugar fermentation) and vitamin A...Too much TNF alpha (an acidic

protein) can do serious eye damage. Vitamin A (another acidic

protein) helps to protect the eyes. The proteins can " down regulate "

or " up regulate " one another...like the minerals (Too little Mg =

too much calcium)...

" No significant difference in vitamin C serum concentration in

examined groups was observed. These results may suggest that low

serum concentrations of vitamin A and E may have influence on

Borrelia burgdorferi infection development. "

PMID: 16013408

TNF alpha...proinflammatory...triggers lipolysis (breakdown of fats)

which would be a good thing, but...it further depletes Mg and we

lose control of glycolysis = insulin resistance soars...hello

diabetes.

I have over 1400 MS word files...piece by piece...WHAT A complex

puzzle this is!

We CAN win...It CAN be done...eliminating this infection, but

IMO..abx. is the wrong way to go...this bugger (along with

mycoplasm) is TOTALLY UNIQUE.

We have to hit it from the cholesterol and glycolysis angle

simultaneously...the ONLY nutrient that can do this is Mg.