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Mothers and mothers ***only*** , chronic fatigue & depression linked to

their children's CFS .

I do make the association in my web site ..I see the same old explanation

“genetics” it's not genetics it's an infectious link. one day they will find

the gene that compels doctors to blame genes for every medical

condition …

http://www.immunesupport.com/library/showarticle.cfm?ID=7170 & Reviewed=YES

Strong Maternal Connection Identified for Adolescents with CFS by Editor

ImmuneSupport.com

06-20-2006

Note: This article includes our follow-up suggestions regarding its

implications for families in which a mother is diagnosed with CFS.

Mothers of adolescents diagnosed with chronic fatigue syndrome (CFS) were

5.3 times more likely to report fatigue, and 8.4 times more likely to report

depression than mothers of healthy adolescents, according to a cross-section

study conducted by physicians at Utrecht University Medical Center in the

Netherlands and reported in the June 2006 issue of the journal Pediatrics.

Mean overall statistics indicate the CFS-patient mothers differed from

mothers of healthy youngsters “on all measurements of fatigue and

fatigue-associated symptoms, including sleep.” And 9 of the 40 CFS-patient

mothers (roughly 22 percent) “fulfilled CDC criteria for CFS.” Importantly,

no such association was found for the fathers of the CFS and healthy

adolescent study cohorts.

Overall, the study seems to add a piece to the body of knowledge regarding

the etiology of CFS, while also generating a host of new issues to be

investigated.

The findings expand upon those of other studies, including for example a

major twin study “confirming the familial aggregation of CFS and suggesting

that genes may play a role,” and CFS “subjects’ reports of illness in first

degree relatives,” suggesting that relatives of patients with CFS had

significantly higher rates of CFS than relatives of patients “with another

chronic illness.”

The authors suggest their study may be the first to discriminate between the

incidence of CFS symptoms in CFS subjects’ mothers and fathers. And they

conclude that “the clustering of symptoms in mother and child suggests

genetic transfer and gene-environment interaction.” Specifically, it “may

point to a gene-environment interaction in which the child not only inherits

the genetic characteristics of the mother, but these maternal

characteristics also function as environment factors for the child.”

Study Design The study involved 40 adolescents diagnosed with CFS according

to Centers for Disease Control and Prevention criteria, and their mothers

and fathers; as well as a healthy control cohort of 36 adolescents and their

mothers and fathers. The groups were closely matched for gender composition,

number of siblings, ages (12 to 18, average age 16), and intact families.

All completed Checklist Individual Strength (CIS) questionnaires regarding

fatigue, Symptom Checklist-90 questionnaires covering fatigue-associated

symptoms and psychopathology, and various other measurement tools.

For more information on this study, see the original article “Mirrored

Symptoms in Mother and Child With Chronic Fatigue Syndrome,” by Elise M. van

de Putte, MD, et al., in the June 2006 issue of the journal Pediatrics, at

http://pediatrics.aappublications.org

What Does This Mean For You?

1. Families in which the mother suffers from CFS should be alert to symptoms

of CFS in their teenaged and young adult children, as the genetic component

and interaction with a CFS sufferer may combine to bring on symptoms earlier

among children who are susceptible.

2. Many symptoms of CFS, such as fatigue, sleep problems, and depression can

be maked or mimicked by normal teenage behaviors and lifestyles. Knowing

that CFS may be genetic can lead to earlier identification, diagnosis, and

treatment to improve outcomes and quality of life for the family.

3. Patients need to be aware that the symptoms manifested by the mother may

increase the symptoms of the teenager through their interactions. The

additional physical and emotional stress of CFS in a parent may accentuate

the symptoms in the child, in both the short and long term.

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