Guest guest Posted April 8, 1999 Report Share Posted April 8, 1999 Martha, take a look at this site for all the info on minocin. I didn't see any great cause for concern. Vern http://www.rxlist.com/cgi/generic/minocycline.htm >I have heard some great results from this antibiotic. However, after >reading some of the material concerning the possibility that one can >have side effects such as hepatitis, or lupus like symptoms while taking >this drug, have you heard anything about this, or is this rare. I >believe in AP, but was a little concerned about these potential risks? >However, what choice do we have really if we do want to get better. I >imagine that through blood work checking liver function while on >minocycline and other tests this could be resolved if needed. Correct? >Any comment is welcomed. I remember someone writing in and saying after >everything really had failed, minocycline had really helped and they >were back dancing much to one of their doctors! Thanks. Martha > >------extPart_000_0004_01BE814C.DFF007E0 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 8, 1999 Report Share Posted April 8, 1999 Dear Martha, It must be borne in mind that adverse side effects from minocycline are very rare and usually occur at much higher doses than those used for this protocol. Lupus patients often take doxycycline just to avoid that possible risk. But in general, this is a very safe antibiotic and blood tests aren't required to monitor its use. People have taken minocycline for decades (literally) at the intermittent, low doses prescribed for this therapy. The term 'AP' was coined by this group and it doesn't refer just to minocycline. The antibiotic used can be tetracycline, minocycline, doxycycline, erythromycin, azithromycin, ciprofloxacin and some others. The body of data that we have available is mainly on minocycline, doxycycline and tetracycline, but some of our doctors are using newer antibiotics with success. Chris. From: and Martha <gmsmith@...> I have heard some great results from this antibiotic. However, after reading some of the material concerning the possibility that one can have side effects such as hepatitis, or lupus like symptoms while taking this drug, have you heard anything about this, or is this rare. I believe in AP, but was a little concerned about these potential risks? However, what choice do we have really if we do want to get better. I imagine that through blood work checking liver function while on minocycline and other tests this could be resolved if needed. Correct? Any comment is welcomed. I remember someone writing in and saying after everything really had failed, minocycline had really helped and they were back dancing much to one of their doctors! Thanks. Martha Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 8, 1999 Report Share Posted April 8, 1999 I am afraid that I must disagree with the statement that regular blood tests are not required to monitor the use of Minocycline. I experienced one of these rare side effects as the blood tests showed that my liver was being damaged by the Minocycline (drug induced hepatitis). Had I not been having regular blood tests, I surely would have continued on a long term course of the Minocycline. This would have been very dangerous. I am looking into starting Doxycycline, now that my liver function tests have returned to a normal level, but would caution against not having regular blood tests as the consequences, even if rare, are quite serious. Just my 2 cents. Dave from Calgary. rheumatic Re: minocycline Dear Martha, It must be borne in mind that adverse side effects from minocycline are very rare and usually occur at much higher doses than those used for this protocol. Lupus patients often take doxycycline just to avoid that possible risk. But in general, this is a very safe antibiotic and blood tests aren't required to monitor its use. People have taken minocycline for decades (literally) at the intermittent, low doses prescribed for this therapy. The term 'AP' was coined by this group and it doesn't refer just to minocycline. The antibiotic used can be tetracycline, minocycline, doxycycline, erythromycin, azithromycin, ciprofloxacin and some others. The body of data that we have available is mainly on minocycline, doxycycline and tetracycline, but some of our doctors are using newer antibiotics with success. Chris. From: and Martha < gmsmith@... <mailto:gmsmith@...> > I have heard some great results from this antibiotic. However, after reading some of the material concerning the possibility that one can have side effects such as hepatitis, or lupus like symptoms while taking this drug, have you heard anything about this, or is this rare. I believe in AP, but was a little concerned about these potential risks? However, what choice do we have really if we do want to get better. I imagine that through blood work checking liver function while on minocycline and other tests this could be resolved if needed. Correct? Any comment is welcomed. I remember someone writing in and saying after everything really had failed, minocycline had really helped and they were back dancing much to one of their doctors! Thanks. Martha Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 9, 1999 Report Share Posted April 9, 1999 I agree...my rheumy does my bloodwork on a regular basis to monitor how I am doing. That is why I still go to one. Can't hurt and we need the info for those clinical studies. Donna Ottawa, Canada Scleroderma, Raynaud's 01/95, AP 10/97 (My Story) www.compmore.net/~donray rheumatic Re: minocycline > > >Dear Martha, > >It must be borne in mind that adverse side effects from minocycline are very >rare and usually occur at much higher doses than those used for this >protocol. Lupus patients often take doxycycline just to avoid that possible >risk. But in general, this is a very safe antibiotic and blood tests aren't >required to monitor its use. People have taken minocycline for decades >(literally) at the intermittent, low doses prescribed for this therapy. > >The term 'AP' was coined by this group and it doesn't refer just to >minocycline. The antibiotic used can be tetracycline, minocycline, >doxycycline, erythromycin, azithromycin, ciprofloxacin and some others. The >body of data that we have available is mainly on minocycline, doxycycline >and tetracycline, but some of our doctors are using newer antibiotics with >success. > >Chris. > >From: and Martha < gmsmith@... <mailto:gmsmith@...> > > > >I have heard some great results from this antibiotic. However, after >reading some of the material concerning the possibility that one can have >side effects such as hepatitis, or lupus like symptoms while taking this >drug, have you heard anything about this, or is this rare. I believe in AP, >but was a little concerned about these potential risks? However, what >choice do we have really if we do want to get better. I imagine that >through blood work checking liver function while on minocycline and other >tests this could be resolved if needed. Correct? Any comment is welcomed. >I remember someone writing in and saying after everything really had failed, >minocycline had really helped and they were back dancing much to one of >their doctors! Thanks. Martha > > >------------------------------------------------------------------------ >Are you hogging all the fun? >http://www.ONElist.com >Friends tell friends about ONElist! > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 22, 2006 Report Share Posted June 22, 2006 http://www.postgradmed.com/issues/1997/04_97/cunha_1.htm Minocycline Minocycline is a second-generation, long-acting tetracycline that was introduced in the same era as doxycycline. The two drugs have many common attributes: long half-life, once- or twice-daily administration, excellent bioavailability, and equivalent blood and tissue levels whether administered intravenously or orally. However, the two drugs differ in several important respects. CNS infection Pharmacokinetically, minocycline and doxycycline are both highly lipid-soluble. However, compared with conventional tetracycline, minocycline is ten times more lipid-soluble whereas doxycycline is only five times more lipid-soluble. The clinical importance of this characteristic is that minocycline has particularly good tissue penetration and excellent CNS penetration; although doxycycline does penetrate the CNS, it does not do so to the degree that is achievable with minocycline. Staphylococcal infection Minocycline's antimicrobial spectrum is very similar to that of doxycycline with one important addition: It has much more antistaphylococcal activity. Minocycline is one of the few drugs that is clinically active against MRSA infection, and it has been used successfully to treat both colonization and infection. Vancomycin is effective against MRSA infection; however, it is not effective in eliminating the carrier state. Additional infections Minocycline may be used to treat legionnaires' disease, Lyme disease, and zoonotic infections. Traditional as well as new and increased uses for minocycline are summarized in table 2 (1,7-9). Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 21, 2006 Report Share Posted July 21, 2006 Lori, Hello -- my name is Hollye from Arkansas -- I am currently on Minocin and it is working wonders for me -- I went from mostly bad days to mostly good days -- I had currently been on pred., MTX -- tried the sulfa drug but the Minocin is working better than those! I hope this helps! Good luck to you and your daughter! Hollye --------------------------------- Music Unlimited - Access over 1 million songs.Try it free. Quote Link to comment Share on other sites More sharing options...
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