Guest guest Posted June 20, 2002 Report Share Posted June 20, 2002 mineral iron is very reactive and not suitable as a mineral supplement. it is typical of corp stupidity that it added to cereals if a fraction of the marketing buget was spent on researching thier additives!!!!!!!!!!!!!!! but people work thier packaged lives and eat packages and the box comes unwound.... > http://www.cfsan.fda.gov/~rdb/opa-g042.html I read the thing I still > don't know what it will do for anyone? ltldab1@ juno.com Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 31, 2002 Report Share Posted December 31, 2002 I think lactoferrin also has the ability to help the gut get rid of excess iron, which bacteria thrive on/in. So it has that bonus, as well as immune system bonuses as well. I use colostrum with both my kids. W Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 6, 2003 Report Share Posted January 6, 2003 Tina, You need cysteine inside cells to help produce your own lactoferrin, as mentioned below, especially if you want to have success against candida. This makes sense because iron binding sites, such as you have in lactoferrin, need to have sulfur to maintain their iron binding capability. The availability of cysteine to cells is furnished through such molecules as cystine, glutathione and mixed disulfides, but if these are having a hard time getting into cells, or being processed inside cells, then intracellular (intra-Golgi) cysteine can be low even if plasma cysteinyl groups are high. So it might be appropriate to enhance this side of the chemistry in someone having intracellular sulfur supply problems. Curiously, both casein and lactoferrin help to preserve the activity of IGF-1, which is a growth factor that is very critical to postnatal brain development and is very tied up with sulfation issues that are going on in the brain postnatally. For that reason, it makes sense that breastmilk includes both casein and lactoferrin since infancy is such an intensive time for the myelination and sulfation of the brain. ...a process that continues through toddlerhood, and in some areas till young adulthood. This process is likely to be delayed in children with developmental delays. But because casein is problematic for other reasons, the lactoferrin might be an alternative way to help preserve the IGF-1 activity. Also, in those with a leaky gut, the leakiness is likely to have been caused by poor sulfation of the gut by molecules such as mucins and glycosaminoglycans. The article below suggests that the glycosaminoglycan heparin in the stomach also helps to preserve IGF-1. That heparin might be undersulfated if the supply of cysteine deep inside the cells is wanting. That could be another reason lactoferrin might furnish a needed boost to sulfation. Kansenshogaku Zasshi 1998 Jul;72(7):727-37 Related Articles, Links [Reverting effect of cysteine on the suppression by glucose or dexamethasone of anti-Candida activity of human neutrophils] [Article in Japanese] Tansho T. Department of Surgery II, Teikyo University School of Medicine. Amino acid mixture prescribed for an hyperalimentation solution (PN-twin) diminishes suppression of anti-Candida activity of neutrophils as reported previously (Tansho, T, et al. J. Jpn. Assoc. Infect. Dis. 70: 463-469). The aim of this study was to identify the active principle in the amino acid mixture and to examine its action mechanism. Amino acid mixture (PN-twin) containing 23 amino acids neutralized the suppression of anti-Candida activity of human neutrophils by 1.0% of glucose. These amino acids were divided to several groups by their structure and effects of the groups on the suppressed anti-Candida activity neutrophils were examined. In all groups tested, amino acids containing cystein and methionine clearly neutralized the suppression, especially cysteine at the concentration more than 20 micrograms/ml significantly recovered the anti-Candida activity of neutrophils which was suppressed in the presence of 1% glucose or 10(-6) M dexamethasone. Correspondingly, cysteine augmented production of lactoferrin by stimulated neutrophils; which functions as a major effector molecule in growth inhibition of Candida by neutrophils. These results suggest that cysteine in alimentation solution augments anti-Candida defense mechanisms through recovery of neutrophil function. PMID: 9745223 [PubMed - indexed for MEDLINE] Degradation of IGF-I in the adult rat gastrointestinal tract is limited by a specific antiserum or the dietary protein casein. Xian CJ, Shoubridge CA, Read LC ative Research Centre for Tissue Growth and Repair, Women's and Children's Hospital, North Adelaide, Australia. To investigate the potential of IGF-I peptides as therapeutics in the gut, the survival profiles of a bolus of 125I-labelled IGF-I (8.6 ng) in vivo in various ligated gut segments of fasted adult rats have been examined. The intactness of IGF-I tracer in the flushed luminal contents was estimated by trichloroacetic acid precipitation, antibody and receptor binding assays. It was found that IGF-I was degraded very rapidly in duodenum and ileum segments with a half-life (t1/2) of 2 min by all three methods. IGF-I was slightly more stable in the stomach (t1/2 = 8, 5 and 2.5 min by the above three methods), and considerably more stable in the colon (t1/2 = 38, 33 and 16 min as judged by the three methods). Rates of degradation in gut flushings in vitro were similar to the in vivo rates except for the colon, where IGF-I was proteolysed more rapidly in vivo. As a means of developing gut-stable and active forms of IGF-I, several approaches were examined for their effectiveness in prolonging IGF-I survival in the upper gut. It was found that the extension peptide on the analogue, LR3IGF-I did not protect IGF-I, nor did association with IGF-binding protein-3. However, an IGF-I antiserum was effective in prolonging IGF-I half-life in duodenum fluid by 28-fold. Charge interaction between IGF-I and heparin could also protect IGF-I in the stomach but not in duodenum flushings. Furthermore, casein (a non-specific dietary protein) and to a lesser extent, BSA and lactoferrin, were effective in preserving IGF-I structural integrity and receptor binding activity in both stomach and duodenum fluids. It can be concluded that IGF-I cannot be expected to retain bioactivity if delivered orally because of rapid proteolysis in the upper gut, but the use of IGF antibodies and casein could represent useful approaches for IGF-I protection in oral formulae. PMID: 7561632, UI: 96030699 At 02:25 PM 12/31/2002 +0000, you wrote: >We have been on the GFCF diet for about 1.5 years without any major >dramatic changes. We will be chelating after we get our test results >back, but I was wondering about lactoferrin, the protective immune >property found in human milk. I read another post in which the >parent talked about the dramatic changes her child experienced after >giving him lactoferrin. She had done the diet and anti-fungals with >no result until she added lactoferrin. She said it was easier to rid >his body of metals after that too. If anyone has any experience or >information on this I would greatly appreciate it. > >Thanks, > >Tina > > >======================================================= > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 2, 2006 Report Share Posted June 2, 2006 Does anyone take lactoferrin? http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/ lac_0314.shtml - Kate Quote Link to comment Share on other sites More sharing options...
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