Fwd: Hematin trial for Lead poisoning and acute intermitten porphyria

[Guest guest]

I just posted the following at CFSFMexperimental. Kind of

interesting that Hematin seems to work for toxin removal not only in

porphyric patients, but in patients with lead poisoning. Hematin

therapy seems to apply primarily to hereditary, acute and

intermittent acute porphyria (not sure if it relates to acquired

porphyria, which Stratton believes we have but has not been heavily

investigated.) I do find it interesting however, that the

ingredients in Hematin are the same that are often discussed for PWC

(minus, perhaps, the iron). (I'm pretty sure the copper is included,

simply because the iron antagonizes it and will deplete it.

Interesting that zinc isn't also included)

penny

--- In , " penny " <pennyhoule@...>

wrote:

Hematin administration to an adult with lead intoxication

JM Lamon, BC Frykholm and DP Tschudy

Lead poisoning and acute intermittent porphyria (AIP) may exhibit

similar neurologic manifestations, and they have in common elevated

excretion of urinary aminolevulinic acid (ALA). Despite their

similarities, the possible pathophysiologic connection between AIP

and lead poisoning in not known. Because intravenous hematin

administration has produced biochemical improvement in AIP, a

hematin trial in lead intoxication was of interest with respect to

some of the heme metabolism abnormalities observed in the condition.

Significant diminution of urinary ALA and coproporphyrin excretion

occurred in association with intravenous hematin administration.

http://www.bloodjournal.org/cgi/content/abstract/53/5/1007

Here's a link to Hematin and its makeup.

I would strongly caution, however, that there are a number of

studies linking the use of hematin with hypercoagulation, something

that should be considered carefully before taking it.

Vitamin C (ascorbic acid, corn free)

100 mg

167%

Folic Acid

400 mcg

100%

Vitamin B-3 (as niacin)

20 mg

100%

Vitamin B-6 (as pyridoxine HCl)

5 mg

250%

Vitamin B-12 (as hydroxocobalamin)

100 mcg

1,667%

Iron (elemental from iron aspartate)

29 mg

161%

Copper (elemental from aspartate)

1.5 mg

75%

Liver Tissue

300 mg

http://www.integratedhealth.com/hpdspec/hema.html

--- End forwarded message ---