RE: Re: I wonder ,,Bacteroides fragilis

[Guest guest]

Thanks for the references Barb ,Yes ,not clear is it, bug balance, bug

synergy it's next to alchemy at the moment ,we scarcely know anything about

how we interact with microbes .I'm just thinking that stopping all ABX maybe

a good idea .The articles do not mention any other medications, it looks

like it's a stand alone therapy , I'll try it for a while without the abx's

...as before i'll post the results ......

[infections] Re: I wonder ,, " Bacteroides

fragilis "

Well- alkalize the gut and antibiotics can kill b. fragilis easier..

SEE ref 1

But it looks like b fragilis can live in varyinh PH to me.

And researchers are worried about abx resistance as alot

of them are not really considered all that friendly...

SEE ref 2

So- back to a bug-balance issue again?

Still wondering about tagamet -

Will be interested in your results.

Barb

REFERENCE 1

Antimicrob. Agents Chemother., Sep 1997, 2047-2049, Vol 41, No. 9

Copyright © 1997 by the American Society for Microbiology. All rights

reserved.

Effect of pH on in vitro antimicrobial susceptibility of the

Bacteroides fragilis group

ME Falagas, L McDermott and DR Snydman

Department of Pathology (Clinical Microbiology), New England Medical

Center and Tufts University School of Medicine, Boston, Massachusetts

02111, USA.

We studied the effect of pH (7.1, 6.3, and 5.8) on the in vitro

susceptibilities of 59 isolates of Bacteroides fragilis and 60

isolates of other B. fragilis group species to trovafloxacin,

ciprofloxacin, clindamycin, ampicillin-sulbactam, piperacillin-

tazobactam, imipenem, and meropenem. For each agent tested the

geometric mean MIC was highest at pH 5.8, intermediate at pH 6.3, and

lowest at pH 7.1. The magnitude of the pH effect varied greatly among

different antibiotics. These data show that an acidic pH decreases

the in vitro susceptibilities of the B. fragilis group to several

antibiotics.

REFERENCE 2

http://www.anaesthetist.com/icu/infect/bacteria/anaerobe/bfrag.htm

>

>

>

> I see that cimetidine is responsible for an increased CD4

(helper/inducer)

> cell count , well that's interesting because latest research has

revealed

> that a particular bacterium is responsible for the production of

CD4 cells

>

> So does a reduced acidic environment favour the growth of

Bacteroides

> fragilis, the bacterium in question?

>

> The answer lies in the gut ..you better believe it

>

>

> Read and savour this wonderful article…

>

> Bacterium Proves Essential to Immune System Development

>

> http://focus.hms.harvard.edu/2005/Jul15_2005/microbiology.shtml

>

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> Internal Virus Database is out-of-date.

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