Guest guest Posted November 1, 2005 Report Share Posted November 1, 2005 Well- based on this- there are alot of Lymerix vaccinees participating in studies. I think there were over 10000 people vaccinated in the East. I wonder why none of them are on line? What is their status? Anyone know? Barb ___________________________________________________________________ Clin Diagn Lab Immunol. 2005 Sep;12(9):1036-40. Detection of immune complexes is not independent of detection of antibodies in Lyme disease patients and does not confirm active infection with Borrelia burgdorferi. Marques AR, Hornung RL, Dally L, Philipp MT. Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-1888, USA. amarques@... The Borrelia burgdorferi-specific immune complex (IC) test, which uses polyethylene glycol (PEG) precipitation to isolate ICs from serum, has been used as a research test in the laboratory diagnosis of early Lyme disease (LD) and has been proposed as a marker of active infection. We examined whether B. burgdorferi-specific antibodies were present within PEG-precipitated ICs (PEG-ICs) in patients with LD, posttreatment Lyme disease syndrome, and controls, including individuals who received the outer surface protein A (OspA) vaccine. Using a B. burgdorferi whole-cell enzyme-linked immunosorbent assay (ELISA), we obtained positive PEG-IC results not only in patients with a history of LD, but also in individuals vaccinated with OspA vaccine. The frequency of positive PEG-IC ELISAs in OspA vaccinees was significantly higher with ELISA-reactive than with ELISA-negative unprocessed serum samples (P=0.001), demonstrating dependency between the tests. Similar results were found using samples from rhesus macaques infected with B. burgdorferi, uninfected macaques vaccinated with OspA, and controls. Therefore, testing for the presence of antibodies against B. burgdorferi in PEG-IC preparations is not more likely to reflect active infection than testing in unprocessed serum and should not be used in individuals who received the OspA vaccine. PMID: 16148168 [PubMed - indexed for MEDLINE] Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 20, 2007 Report Share Posted May 20, 2007 First Welcome to the Group ... Second, you could still have gotten it by its own, its not particular to whom it really wants to attack lol... But I sure would check out the facts with your doctor just in case... But I have never heard of the vaccine myself... Love and peace always Shaun and Barb Quote Link to comment Share on other sites More sharing options...
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