es disease is refractory to treatment

[Guest guest]

But probably most interesting of all is that es disease, the

natural MAC gut infection of ruminant animals, is refractory to

antimicrobial chemotherapy:

http://www.pubmedcentral.gov/picrender.fcgi?artid=171590 & blobtype=pdf

Yet MBCs of several common drugs were below therapeutic

concentrations.

There it is again, the Main Enigma.

Assuming the canonical understanding of it to be correct, this is the

first regularly-occuring refractory infectious disease I have learned

about in any non-human. I'd say odds are about 70% that whatever

prevents rapid cure of es disease and most of our diseases is the

same phenomenon - whether one we may eventually be able to get around,

or not.

[Guest guest]

Hmm, according to this one its not totally clinically refractory,

rather the trouble is its not totally eradicable.

http://jds.fass.org/cgi/reprint/81/1/283.pdf

It may be partially refractory. I'll figure it out eventually.

>

> But probably most interesting of all is that es disease, the

> natural MAC gut infection of ruminant animals, is refractory to

> antimicrobial chemotherapy:

>

> http://www.pubmedcentral.gov/picrender.fcgi?

artid=171590 & blobtype=pdf

>

> Yet MBCs of several common drugs were below therapeutic

> concentrations.

>

> There it is again, the Main Enigma.

>

> Assuming the canonical understanding of it to be correct, this is

the

> first regularly-occuring refractory infectious disease I have

learned

> about in any non-human. I'd say odds are about 70% that whatever

> prevents rapid cure of es disease and most of our diseases is

the

> same phenomenon - whether one we may eventually be able to get

around,

> or not.

>