Re: ARBs, Vitamin D, TNF-alpha, TLR4, CD40, Adiponectin, the Universe & Everything.

[Guest guest]

Mark

Well done..

tony

> Months ago someone sent me an email about the experimental

treatment

> protocol for various health conditions, which uses Benicar, avoids

> vitamin D, and later uses minocycline. Since then, I've ended up

> spending way too much of my online time, reading studies relating

to

> the protocol and the diseases it's supposed to treat.

Occasionally in

> my readings, I would find something interesting.

>

> For example, there is a fairly new theory of why pain and fatigue

> occurs in sarcoidosis. Apparently many people with sarcoidosis

have a

> condition known as small fiber neuropathy, which is not very easy

to

> diagnose, so it's easy to overlook. This could be the real cause

of

> many of the obscure symptoms in sarcoidosis, which the experimental

> protocol instead believes is due to excess vitamin D.

>

> One of the main beliefs of the protocol is that vitamin D is being

> produced by the immune system in many diseases, and that this is

> responsible for some of the disease symptoms. But the medical

> literature only mentions a few specific diseases where this

production

> contributes noticable amounts of vitamin D to the circulating

levels.

> Sarcoidosis and Crohn's disease are 2 such diseases. I did a lot

of

> reading about those diseases.

>

> I created a simple web page where I list some of the more

interesting

> facts I learned from the studies I read. It's a bit too long to

post,

> but I think that some people here might be interested in reading

some

> of it. See here:

>

> http://web.mit.edu/london/www/universe.html

>

> Since I initially was interested in vitamin D and calcium

metabolism

> (i.e. why does hypercalcemia occur sometimes but not others), my

web

> page starts by talking about that, and then later I talk about

studies

> that relate to angiotnesin II and inflammation. I include a bit of

> introductory information, which probably most people here know, but

> eventually I do get to some good stuff.

>

> Hopefully, someone out there might find these facts as interesting

as

> I did. The main intent of my writing it, was to show what's

occurring

> in well recognized vitamin D producing inflammatory conditions, and

> show why it might be possible that the experimental protocol might

> help those conditions. Once one understands this, it hopefully

would

> make it clearer for people to answer the question of whether such a

> protocol would have any use for other conditions, such as

fibromyalgia

> and CFS. I have mainly left the answering of that question up to

the

> reader themselves.

>

> Have fun reading it.

>

> Mark