RE: Re: Microbe (fungus) killing by medium chain Fatty Acids

[Guest guest]

Barb, I attended a conference last Wednesday one of the lectures I attended was "Infection a cause of Cancer" given by a Max Parkin ...It didn't make for a comfortable hour or so of listening..A couple of topics were the involvement of Helicobacter Pylori & Epsine Bar Virus ..HP it turns out infects 50% of us in the west & it's highly cacogenic!!! Almost everyone carries the EBV ...he puzzled on how the virus became pathogenic in some. I collared him at the end of the lecture and asked had he considered stealth pathogens ..he asked which one in particular .the obvious model was chlamidyia oh , good one that ,i'll make a note of it..I gave him a bit of our tale, said i was concerned that plainly endemic infections were simply just ignored,but he didn't want to know ..Sadly the conclusion of the presentation was that infection was the cause of approx 22% of all cancers ..he did say it was a conservative estimate ..very conservative i'd say ..

-----Original Message-----From: infections [mailto:infections ]On Behalf Of Barb PeckSent: 10 October 2005 13:08infections Subject: [infections] Re: Microbe (fungus) killing by medium chain Fatty AcidsHey you guys......... Don't forget that there are natural agents that are excellentat killing yeast (and they don't build in resistance to the microbe). On my original Candida Panel (LabCorp) I had a 2.5 IgA titer(< 0.8 is normal) and IgM and IgG were psuhing the normal limits.I didn't use drugs to grt rids of it - I wanted to try enzymes or natural products first (becuase I didn't want to create a superinfection of resistant mutants). I used Nystatin, Candex and Coconut oil(which is like 50% Lauric Acid). I was using lauricidin previous to coconut oil- but swicthed to the oil because I suspect it metabolizes easier. And the same oil you ingest, you can put on your skin. It took over 8 months for my titer dropped to normal- but that might have been a reflection of how long it takes the titer to drop. The other thing to remember about long term abx is frequent sore throats: The last I looked at the stastics of people on long term abx therapy for acne- showed those people getting sore thraots due to the imbalance of flora in the throat.So I think you HAVE to address fungal issues while on abx - or your just trading one problem for another.Barb Antimicrob Agents Chemother. 2001 Nov;45(11):3209-12.In vitro killing of Candida albicans by fatty acids and monoglycerides.Bergsson G, Arnfinnsson J, Steingrimsson O, Thormar H.Institute of Biology, University of Iceland, Reykjavik, Iceland. gudmunb@...The susceptibility of Candida albicans to several fatty acids and their 1-monoglycerides was tested with a short inactivation time, and ultrathin sections were studied by transmission electron microscopy (TEM) after treatment with capric acid. The results show that capric acid, a 10-carbon saturated fatty acid, causes the fastest and most effective killing of all three strains of C. albicans tested, leaving the cytoplasm disorganized and shrunken because of a disrupted or disintegrated plasma membrane. Lauric acid, a 12-carbon saturated fatty acid, was the most active at lower concentrations and after a longer incubation time.PMID: 11600381 [PubMed - indexed for MEDLINE] ____________________________________________________________________Antimicrob Agents Chemother. 1998 Sep;42(9):2290-4.In vitro inactivation of Chlamydia trachomatis by fatty acids and monoglycerides.Bergsson G, Arnfinnsson J, Karlsson SM, Steingrimsson O, Thormar H.Institute of Biology, University of Iceland, Reykjavik, Iceland.The antichlamydial effects of several fatty acids and monoglycerides were studied by incubating Chlamydia trachomatis bacteria with equal volumes of lipid solutions for 10 min and measuring the reduction in infectivity titer compared with that in a control solution without lipid. Caprylic acid (8:0), monocaprylin (8:0), monolaurin (12:0), myristic acid (14:0), palmitoleic acid (16:1), monopalmitolein (16:1), oleic acid (18:1), and monoolein (18:1) at concentrations of 20 mM (final concentration, 10 mM) had negligible effects on C. trachomatis. In contrast, lauric acid (12:0), capric acid (10:0), and monocaprin (10:0) caused a greater than 10,000-fold (>4-log10) reduction in the infectivity titer. When the fatty acids and monoglycerides were further compared at lower concentrations and with shorter exposure times, lauric acid was more active than capric acid and monocaprin was the most active, causing a greater than 100, 000-fold (>5-log10) inactivation of C. trachomatis at a concentration of 5 mM for 5 min. The high levels of activity of capric and lauric acids and particularly that of monocaprin are notable and suggest that these lipids have specific antichlamydial effects. The mode of action of monocaprin was further studied by removal of the lipid by centrifugation before inoculation of Chlamydia onto host cells and by electron microscopy. The results indicate that the bacteria are killed by the lipid, possibly by disrupting the membrane(s) of the elementary bodies. A 50% effective concentration of 30 microgram/ml was found by incubation of Chlamydia with monocaprin for 2 h. The rapid inactivation of large numbers of C. trachomatis organisms by monocaprin suggests that it may be useful as a microbicidal agent for the prevention of the sexual transmission of C. trachomatis.PMID: 9736551 [PubMed - indexed for MEDLINE] Or this page in PUBMEDhttp://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed & cmd=Display & dopt=pubmed_pubmed & from_uid=11600381

[Guest guest]

On Monday, October 10, 2005, at 09:08 AM, Barb Peck wrote:

>    Don't forget that there are natural agents that are excellent

> at killing yeast (and they don't build in resistance to the microbe).

> ...

>    I used Nystatin, Candex and Coconut oil(which is like 50% Lauric

> Acid).  I was using lauricidin previous to coconut oil- but swicthed

> to the oil because I suspect it metabolizes easier. And the same oil

> you ingest, you can put on your skin.

Barb, I've been taking Lauricidin and meaning to order Candex (always a

pain to have stuff sent to Canada). I'll definitely use these things,

but have been in the situation of needing some immediate relief.

With the Nystatin, should it be used regularly, or just brought in when

the natural stuff isn't able to hold down the fort?

- Kate