why not use subjects own serum in IEM?

[Guest guest]

OK, say you want to look for bacteria in a subject using

immunoelectron microscopy. You need antibody to the bacteria, but

maybe you dont know what their in vivo antigenic profile might be, or

really you might not even know what taxa youre looking for. So you

dont know what antibody to use.

So why not obtain antibody from the subjects own blood? Or, better,

pool it from several subjects who all have the disease phenotype of

interest?

Anyone ever hear of this? Ibrahim did something like this in MS, at

least sorta, but I've never heard of it elsewhwere. I just searched

[autologous IEM {serum/immunoglobulin/antibody}] in pubmed and got

nothin. What gives.