New discovered role of Vitamin D3 to moderate Immune System

[Guest guest]

" How a newly discovered mechanism keeps inflammation under control - "

" The purpose may be suppression of the inflammatory reaction, before

it overshoots the mark " . If this would happen, it could prove to be

more dangerous to the organism than the invader itself. Uncontrolled,

activated macrophages can cause severe damage and even total

destruction of body tissue. Thus, the incorporated vitamin D3 brake

makes sure that the body's own body guards are kept back soon after

their activation. "

http://www.medicalnewstoday.com/medicalnews.php?newsid=29752

" In conclusion, our data indicate that the production of 1,25(OH)2D3

by IFN--stimulated macrophages might be an important negative

feedback mechanism to control innate and inflammatory responses of

activated macrophages. "

http://www.bloodjournal.org/cgi/content/abstract/2005-03-1029v1

This suggests that low Vitamin-D levels may play a significant role

in Autoimmune system, because it's absence allows the immune-system

to stay upregulated.