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All sources , The more crucial core information came from specialist docs Truss, Cranton , & Crook ...but I have built a knowledge base from patient testimony's and looking at the overall picture with gut dysbiosis in mind.....I have found nothing to lead me to think otherwise ...I have corresponded in the not too distant past with doctors who before me had no experience with yeast & dysbiosis... they now treat routinely ..I do meet people who are obviously ill with a yeast infection ..Little story...

Just a few weeks ago I was telling the tale of endemic yeast to a friend I see at the local pub...My wife's got that, he said .So next meeting his wife came along with him , I gave her the full story ....Judy [his wife ] took matters into her own hands and found a lab [near Cambridge?] took the antibody tests, and guess what, all three came up positive ... Off to her GP with the advice from the lab to seek "immediate medical attention" ...Her GP was impressed ,but wanted a few opinions on how to treat ..Gave Judy a further appointment , where treatment she understood would be instigated...But it wasn't ...Judy was practically thrown out of the practice ...Yeast treatment UK style...I am now teaching her the arts of self-treating ...

I'll just take the opportunity to trot this very telling article out ...You better believe it, as they say & thanks for the extract ..what a strange set of results ,just shows how intertwined & symbiotic our gut flora is ...

Article by Dr Truss… In 1953 Dr Orian Truss discovered the devastating effects of antibiotics in Alabama (USA)

Lack of energy and digestive disturbances, arthritic joint pains, skin disease, menstrual problems, emotional instability and depression. All symptoms of what I call the 'antibiotic syndrome' which have greatly increased in frequency in recent years.

On further examination, more symptoms may be discovered. Most of the gastro-intestinal tract is tender when pressed, especially the small intestine, liver and gall bladder. There may even have been a gall bladder operation that failed to improve the condition, sometimes even worsening the symptoms.

There could be a history of thrush or oral, anal or vaginal itching. When these are present the diagnosis of Candida is obvious but it may also be present in the absence of these manifestations and that can be somewhat confusing. The yeast or fungus Candida albicans, of course, thrives during antibiotic treatment. I regard it as reckless negligence to prescribe antibiotics without simultaneous fungicides and replacement therapy with lactobacilli afterwards. I believe that this practice has greatly added to our vast pool of a chronically sick population.

However, the 'antibiotic syndrome' is not just due to Candida. I regard it more generally as a 'dysbiosis' where the wrong kind of microbes inhabit the intestinal tract, not just Candida and other fungi, but many types of pathogenic bacteria including coli bacteria which are normal in the colon but become disease-forming when they ascend into the small intestine.

If the problem has existed for years, there is usually a lack of gastric acid which then allows the stomach to be colonised by microbes, causing inflammation with pain and later, ulcers. The toxins released by the microbial overpopulation cause in addition chronic inflammation of the liver, gall bladder, pancreas and intestines. I regard it as rather likely that a chronic inflammation of the pancreas is a major contributing factor in the development of insulin-dependent diabetes.

Bacterial attack

Specific types of pathogenic bacteria appear to cause or contribute to specific auto-immune diseases. One variety of coli bacteria, for instance, produces a molecule that is very similar to insulin. When the immune system becomes activated against this molecule it may then also attack related features at the beta cells of the pancreas

Another type of bacteria, Yersinia enterocolitica, induces an immune response that attacks the thyroid gland and leads to Grave's disease with a serious overproduction of thyroid hormones.

Ulcerative colitis is linked to overgrowth with pathogenic microbes, the same as Crohn's disease, osteoporosis and ankylosing spondylitis. In ankylosing spondylitis the vertebra of the spine fuse together causing stiffness and pain. Other joints may in time become affected.

Klebsiella, another type of pathogenic bacteria, produces a molecule that is similar to a tissue type found in people with this disease. When klebsiella numbers in the gut decrease, related antibodies in the blood decrease and the condition improves.

Rheumatoid arthritis is linked to other bacteria, called proteus. Proteus is also a common cause of urinary tract infections. Women suffer urinary tract infections as well as rheumatoid arthritis twice as often as men, while men usually have higher levels of klebsiella and three times more ankylosing spondylitis than women.

In addition microbial overgrowth dam ages the intestinal wall so that only partly digested food particles can pass into the bloodstream, causing allergies. In this way all auto-immune diseases can be linked to food allergies.

While rheumatoid arthritis is a frequent feature of the antibiotic syndrome, and I regard it as relatively easy to cure, not many sufferers of this disease seem to be interested in this natural approach. The other day a young man with severe rheumatoid arthritis knocked at my door to collect money for a medically sponsored walkathon. When I told him that I do not give money for drug treatment as it can be overcome with natural therapies, he shouted: 'You are mad!' and left visibly upset.

Other auto-immune diseases that have so far been linked to dysbiosis are psoriasis, lupus erythematosus and pancreatitis. When remedies are given that bind bacterial endotoxins, these conditions usually improve. A further consequence of dysbiosis is susceptibility to food poisoning as with salmonella bacteria, while a healthy intestinal flora prevents these from multiplying and causing trouble.

Staphylococcus aureus or golden staph cause serious infections in hospital patients. It has been found that not only golden staph but also other infections are greatly potentised when they occur with a Candida overgrowth. As Candida overgrowth is a natural outcome of the standard hospital treatment, it is easy to see why golden staph is so deadly in hospitals.

A similar picture emerges with AIDS. People do not die from the AIDS virus but from Candida-potentised bacterial infections. I also see the antibiotic-induced dysbiosis in babies and infants as the main cause of their frequent infections, glue ear and greatly contributing to cot death.

While it used to be uncommon for children to have more than one or two infections a year, now more than six is the norm.

In the 1940's Candida was found in only three per cent of autopsies, now the figure is nearer thirty per cent. There are, of course, other factors that can cause dysbiosis - the contraceptive pill, steroids and other drugs, radiation treatment and chemotherapy - but the main culprit is, without doubt, antibiotics.

Closely related to Candida are the mycoplasms or pleomorphic organisms. These have been shown to be a main factor in the causation of cancer. Therefore, antifungal therapy has also major benefits in cancer treatment.

Dr Orian Truss

-----Original Message-----From: infections [mailto:infections ]On Behalf Of Sent: 23 August 2005 18:33infections Subject: [infections] J - gutsDo you support your gut-symbiosis emphasis mostly from observing the circumstances/course of human illness as reported in patient testimony online?Have you seen this one?Arthritis Rheum. 2000 Nov;43(11):2583-9. Related Articles, Links Oral antibiotics as a novel therapy for arthritis: evidence for a beneficial effect of intestinal Escherichia coli.Nieuwenhuis EE, Visser MR, Kavelaars A, Cobelens PM, Fleer A, Harmsen W, Verhoef J, Akkermans LM, Heijnen CJ.Wilhelmina Children's Hospital, Utrecht, The Netherlands.OBJECTIVE: The intestinal flora is thought to play an important role in regulation of immune responses. We investigated the effects of changing the intestinal flora on the course of adjuvant-induced arthritis (AIA) and on experimental autoimmune encephalomyelitis (EAE) by the use of oral antibiotics. METHODS: Oral treatment with either vancomycin or vancomycin, tobramycin, and colistin was started after AIA and EAE induction. Clinical symptoms of AIA and EAE were monitored, and microbial analysis of ileal samples was performed. RESULTS: Oral vancomycin treatment after disease induction significantly decreased clinical symptoms of AIA. Simultaneously, increased concentrations of Escherichia coli were detected in the distal ileum of vancomycin-treated rats. Ileal concentrations of E coli were inversely related to disease scores in rats with AIA. Coadministration of colistin/tobramycin to prevent the increase in E coli abrogated the beneficial effect of vancomycin on AIA. Vancomycin treatment also reduced the clinical symptoms of EAE. CONCLUSION: We propose oral vancomycin as a novel therapeutic strategy in autoimmune diseases.PMID: 11083284 [PubMed - indexed for MEDLINE]

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I'm 100% with you on the gut dysbiosis and really am finding this

challege/hurdle the hardest to overcome. I just know how important

good stools are.

tony

> All sources , The more crucial core information came from

specialist

> docs Truss, Cranton , & Crook ...but I have built a knowledge base

from

> patient testimony's and looking at the overall picture with gut

dysbiosis in

> mind.....I have found nothing to lead me to think otherwise ...I

have

> corresponded in the not too distant past with doctors who before

me had no

> experience with yeast & dysbiosis... they now treat routinely ..I

do meet

> people who are obviously ill with a yeast infection ..Little

story...

> Just a few weeks ago I was telling the tale of endemic yeast to a

friend I

> see at the local pub...My wife's got that, he said .So next

meeting his wife

> came along with him , I gave her the full story ....Judy [his

wife ] took

> matters into her own hands and found a lab [near Cambridge?] took

the

> antibody tests, and guess what, all three came up positive ... Off

to her GP

> with the advice from the lab to seek " immediate medical

attention " ...Her GP

> was impressed ,but wanted a few opinions on how to treat ..Gave

Judy a

> further appointment , where treatment she understood would be

> instigated...But it wasn't ...Judy was practically thrown out of

the

> practice ...Yeast treatment UK style...I am now teaching her the

arts of

> self-treating ...

>

> I'll just take the opportunity to trot this very telling article

out ...You

> better believe it, as they say & thanks for the extract ..what a

strange

> set of results ,just shows how intertwined & symbiotic our gut

flora is

> ...

>

> Article by Dr Truss… In 1953 Dr Orian Truss discovered the

devastating

> effects of antibiotics in Alabama (USA)

>

> Lack of energy and digestive disturbances, arthritic joint pains,

skin

> disease, menstrual problems, emotional instability and depression.

All

> symptoms of what I call the 'antibiotic syndrome' which have

greatly

> increased in frequency in recent years.

>

> On further examination, more symptoms may be discovered. Most of

the

> gastro-intestinal tract is tender when pressed, especially the

small

> intestine, liver and gall bladder. There may even have been a gall

bladder

> operation that failed to improve the condition, sometimes even

worsening the

> symptoms.

>

> There could be a history of thrush or oral, anal or vaginal

itching. When

> these are present the diagnosis of Candida is obvious but it may

also be

> present in the absence of these manifestations and that can be

somewhat

> confusing. The yeast or fungus Candida albicans, of course,

thrives during

> antibiotic treatment. I regard it as reckless negligence to

prescribe

> antibiotics without simultaneous fungicides and replacement

therapy with

> lactobacilli afterwards. I believe that this practice has greatly

added to

> our vast pool of a chronically sick population.

>

> However, the 'antibiotic syndrome' is not just due to Candida. I

regard it

> more generally as a 'dysbiosis' where the wrong kind of microbes

inhabit the

> intestinal tract, not just Candida and other fungi, but many types

of

> pathogenic bacteria including coli bacteria which are normal in

the colon

> but become disease-forming when they ascend into the small

intestine.

>

> If the problem has existed for years, there is usually a lack of

gastric

> acid which then allows the stomach to be colonised by microbes,

causing

> inflammation with pain and later, ulcers. The toxins released by

the

> microbial overpopulation cause in addition chronic inflammation of

the

> liver, gall bladder, pancreas and intestines. I regard it as

rather likely

> that a chronic inflammation of the pancreas is a major

contributing factor

> in the development of insulin-dependent diabetes.

>

> Bacterial attack

>

> Specific types of pathogenic bacteria appear to cause or

contribute to

> specific auto-immune diseases. One variety of coli bacteria, for

instance,

> produces a molecule that is very similar to insulin. When the

immune system

> becomes activated against this molecule it may then also attack

related

> features at the beta cells of the pancreas

>

> Another type of bacteria, Yersinia enterocolitica, induces an

immune

> response that attacks the thyroid gland and leads to Grave's

disease with a

> serious overproduction of thyroid hormones.

>

> Ulcerative colitis is linked to overgrowth with pathogenic

microbes, the

> same as Crohn's disease, osteoporosis and ankylosing spondylitis.

In

> ankylosing spondylitis the vertebra of the spine fuse together

causing

> stiffness and pain. Other joints may in time become affected.

>

> Klebsiella, another type of pathogenic bacteria, produces a

molecule that is

> similar to a tissue type found in people with this disease. When

klebsiella

> numbers in the gut decrease, related antibodies in the blood

decrease and

> the condition improves.

>

> Rheumatoid arthritis is linked to other bacteria, called proteus.

Proteus is

> also a common cause of urinary tract infections. Women suffer

urinary tract

> infections as well as rheumatoid arthritis twice as often as men,

while men

> usually have higher levels of klebsiella and three times more

ankylosing

> spondylitis than women.

>

> In addition microbial overgrowth dam ages the intestinal wall so

that only

> partly digested food particles can pass into the bloodstream,

causing

> allergies. In this way all auto-immune diseases can be linked to

food

> allergies.

>

> While rheumatoid arthritis is a frequent feature of the antibiotic

syndrome,

> and I regard it as relatively easy to cure, not many sufferers of

this

> disease seem to be interested in this natural approach. The other

day a

> young man with severe rheumatoid arthritis knocked at my door to

collect

> money for a medically sponsored walkathon. When I told him that I

do not

> give money for drug treatment as it can be overcome with natural

therapies,

> he shouted: 'You are mad!' and left visibly upset.

>

> Other auto-immune diseases that have so far been linked to

dysbiosis are

> psoriasis, lupus erythematosus and pancreatitis. When remedies are

given

> that bind bacterial endotoxins, these conditions usually improve.

A further

> consequence of dysbiosis is susceptibility to food poisoning as

with

> salmonella bacteria, while a healthy intestinal flora prevents

these from

> multiplying and causing trouble.

>

> Staphylococcus aureus or golden staph cause serious infections in

hospital

> patients. It has been found that not only golden staph but also

other

> infections are greatly potentised when they occur with a Candida

overgrowth.

> As Candida overgrowth is a natural outcome of the standard hospital

> treatment, it is easy to see why golden staph is so deadly in

hospitals.

>

> A similar picture emerges with AIDS. People do not die from the

AIDS virus

> but from Candida-potentised bacterial infections. I also see the

> antibiotic-induced dysbiosis in babies and infants as the main

cause of

> their frequent infections, glue ear and greatly contributing to

cot death.

>

> While it used to be uncommon for children to have more than one or

two

> infections a year, now more than six is the norm.

>

> In the 1940's Candida was found in only three per cent of

autopsies, now the

> figure is nearer thirty per cent. There are, of course, other

factors that

> can cause dysbiosis - the contraceptive pill, steroids and other

drugs,

> radiation treatment and chemotherapy - but the main culprit is,

without

> doubt, antibiotics.

>

> Closely related to Candida are the mycoplasms or pleomorphic

organisms.

> These have been shown to be a main factor in the causation of

cancer.

> Therefore, antifungal therapy has also major benefits in cancer

treatment.

>

> Dr Orian Truss

>

> [infections] J - guts

>

>

> Do you support your gut-symbiosis emphasis mostly from observing

the

> circumstances/course of human illness as reported in patient

> testimony online?

>

> Have you seen this one?

>

>

>

> Arthritis Rheum. 2000 Nov;43(11):2583-9. Related Articles, Links

>

> Oral antibiotics as a novel therapy for arthritis: evidence for a

> beneficial effect of intestinal Escherichia coli.

>

> Nieuwenhuis EE, Visser MR, Kavelaars A, Cobelens PM, Fleer A,

Harmsen

> W, Verhoef J, Akkermans LM, Heijnen CJ.

>

> Wilhelmina Children's Hospital, Utrecht, The Netherlands.

>

> OBJECTIVE: The intestinal flora is thought to play an important

role

> in regulation of immune responses. We investigated the effects of

> changing the intestinal flora on the course of adjuvant-induced

> arthritis (AIA) and on experimental autoimmune encephalomyelitis

> (EAE) by the use of oral antibiotics. METHODS: Oral treatment

with

> either vancomycin or vancomycin, tobramycin, and colistin was

started

> after AIA and EAE induction. Clinical symptoms of AIA and EAE

were

> monitored, and microbial analysis of ileal samples was performed.

> RESULTS: Oral vancomycin treatment after disease induction

> significantly decreased clinical symptoms of AIA. Simultaneously,

> increased concentrations of Escherichia coli were detected in the

> distal ileum of vancomycin-treated rats. Ileal concentrations of

E

> coli were inversely related to disease scores in rats with AIA.

> Coadministration of colistin/tobramycin to prevent the increase

in E

> coli abrogated the beneficial effect of vancomycin on AIA.

Vancomycin

> treatment also reduced the clinical symptoms of EAE. CONCLUSION:

We

> propose oral vancomycin as a novel therapeutic strategy in

autoimmune

> diseases.

>

> PMID: 11083284 [PubMed - indexed for MEDLINE]

>

>

>

>

>

>

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Actually Tony, you can have designer stools & still have a dysbiosis !! But strange coloured or any unusual change including constipation is a good indicator ..Many of the poor kids with autism have orange stools it indicates a vastly different flora to what is considered normal ..This info gives a good insight..There are some good references [6 & 7] that are worth looking up ..see what you think ..

http://www.probiotictherapy.com.au/physicians/diseases_2.html

[infections] J - guts> > > Do you support your gut-symbiosis emphasis mostly from observing the> circumstances/course of human illness as reported in patient> testimony online?> > Have you seen this one?> > > > Arthritis Rheum. 2000 Nov;43(11):2583-9. Related Articles, Links> > Oral antibiotics as a novel therapy for arthritis: evidence for a> beneficial effect of intestinal Escherichia coli.> > Nieuwenhuis EE, Visser MR, Kavelaars A, Cobelens PM, Fleer A, Harmsen> W, Verhoef J, Akkermans LM, Heijnen CJ.> > Wilhelmina Children's Hospital, Utrecht, The Netherlands.> > OBJECTIVE: The intestinal flora is thought to play an important role> in regulation of immune responses. We investigated the effects of> changing the intestinal flora on the course of adjuvant-induced> arthritis (AIA) and on experimental autoimmune encephalomyelitis> (EAE) by the use of oral antibiotics. METHODS: Oral treatment with> either vancomycin or vancomycin, tobramycin, and colistin was started> after AIA and EAE induction. Clinical symptoms of AIA and EAE were> monitored, and microbial analysis of ileal samples was performed.> RESULTS: Oral vancomycin treatment after disease induction> significantly decreased clinical symptoms of AIA. Simultaneously,> increased concentrations of Escherichia coli were detected in the> distal ileum of vancomycin-treated rats. Ileal concentrations of E> coli were inversely related to disease scores in rats with AIA.> Coadministration of colistin/tobramycin to prevent the increase in E> coli abrogated the beneficial effect of vancomycin on AIA. Vancomycin> treatment also reduced the clinical symptoms of EAE. CONCLUSION: We> propose oral vancomycin as a novel therapeutic strategy in autoimmune> diseases.> > PMID: 11083284 [PubMed - indexed for MEDLINE]> > > > > >

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I can't get thru. I did find it interesting after reading the rest

of the article how oral vancomycin made a huge difference to the gut.

I tend to speculate that the body is trying to rid itself of toxins

that cause this condition and I am often afraid that the toxins may

have created permanent damage making conditions like malabsorption

irreversable.And there's that other condition that is just evading

me at present.Possably another syndrome.

I do also know that crohn's and IBS ain't that far apart, the

crohn's patient has difficulty healing and normally dies from just

such a problem.But again I just wish they could identify the toxins

causing these problems instead of the speculation that turns us

against each other.

tony

> > All sources , The more crucial core information came from

> specialist

> > docs Truss, Cranton , & Crook ...but I have built a knowledge

base

> from

> > patient testimony's and looking at the overall picture with gut

> dysbiosis in

> > mind.....I have found nothing to lead me to think

otherwise ...I

> have

> > corresponded in the not too distant past with doctors who

before

> me had no

> > experience with yeast & dysbiosis... they now treat

routinely ..I

> do meet

> > people who are obviously ill with a yeast infection ..Little

> story...

> > Just a few weeks ago I was telling the tale of endemic yeast

to a

> friend I

> > see at the local pub...My wife's got that, he said .So next

> meeting his wife

> > came along with him , I gave her the full story ....Judy [his

> wife ] took

> > matters into her own hands and found a lab [near Cambridge?]

took

> the

> > antibody tests, and guess what, all three came up positive ...

Off

> to her GP

> > with the advice from the lab to seek " immediate medical

> attention " ...Her GP

> > was impressed ,but wanted a few opinions on how to

treat ..Gave

> Judy a

> > further appointment , where treatment she understood would be

> > instigated...But it wasn't ...Judy was practically thrown out

of

> the

> > practice ...Yeast treatment UK style...I am now teaching her

the

> arts of

> > self-treating ...

> >

> > I'll just take the opportunity to trot this very telling

article

> out ...You

> > better believe it, as they say & thanks for the

extract ..what a

> strange

> > set of results ,just shows how intertwined & symbiotic our gut

> flora is

> > ...

> >

> > Article by Dr Truss… In 1953 Dr Orian Truss discovered the

> devastating

> > effects of antibiotics in Alabama (USA)

> >

> > Lack of energy and digestive disturbances, arthritic joint

pains,

> skin

> > disease, menstrual problems, emotional instability and

depression.

> All

> > symptoms of what I call the 'antibiotic syndrome' which have

> greatly

> > increased in frequency in recent years.

> >

> > On further examination, more symptoms may be discovered. Most

of

> the

> > gastro-intestinal tract is tender when pressed, especially the

> small

> > intestine, liver and gall bladder. There may even have been a

gall

> bladder

> > operation that failed to improve the condition, sometimes even

> worsening the

> > symptoms.

> >

> > There could be a history of thrush or oral, anal or vaginal

> itching. When

> > these are present the diagnosis of Candida is obvious but it

may

> also be

> > present in the absence of these manifestations and that can be

> somewhat

> > confusing. The yeast or fungus Candida albicans, of course,

> thrives during

> > antibiotic treatment. I regard it as reckless negligence to

> prescribe

> > antibiotics without simultaneous fungicides and replacement

> therapy with

> > lactobacilli afterwards. I believe that this practice has

greatly

> added to

> > our vast pool of a chronically sick population.

> >

> > However, the 'antibiotic syndrome' is not just due to Candida.

I

> regard it

> > more generally as a 'dysbiosis' where the wrong kind of

microbes

> inhabit the

> > intestinal tract, not just Candida and other fungi, but many

types

> of

> > pathogenic bacteria including coli bacteria which are normal in

> the colon

> > but become disease-forming when they ascend into the small

> intestine.

> >

> > If the problem has existed for years, there is usually a lack

of

> gastric

> > acid which then allows the stomach to be colonised by microbes,

> causing

> > inflammation with pain and later, ulcers. The toxins released

by

> the

> > microbial overpopulation cause in addition chronic

inflammation of

> the

> > liver, gall bladder, pancreas and intestines. I regard it as

> rather likely

> > that a chronic inflammation of the pancreas is a major

> contributing factor

> > in the development of insulin-dependent diabetes.

> >

> > Bacterial attack

> >

> > Specific types of pathogenic bacteria appear to cause or

> contribute to

> > specific auto-immune diseases. One variety of coli bacteria,

for

> instance,

> > produces a molecule that is very similar to insulin. When the

> immune system

> > becomes activated against this molecule it may then also attack

> related

> > features at the beta cells of the pancreas

> >

> > Another type of bacteria, Yersinia enterocolitica, induces an

> immune

> > response that attacks the thyroid gland and leads to Grave's

> disease with a

> > serious overproduction of thyroid hormones.

> >

> > Ulcerative colitis is linked to overgrowth with pathogenic

> microbes, the

> > same as Crohn's disease, osteoporosis and ankylosing

spondylitis.

> In

> > ankylosing spondylitis the vertebra of the spine fuse together

> causing

> > stiffness and pain. Other joints may in time become affected.

> >

> > Klebsiella, another type of pathogenic bacteria, produces a

> molecule that is

> > similar to a tissue type found in people with this disease.

When

> klebsiella

> > numbers in the gut decrease, related antibodies in the blood

> decrease and

> > the condition improves.

> >

> > Rheumatoid arthritis is linked to other bacteria, called

proteus.

> Proteus is

> > also a common cause of urinary tract infections. Women suffer

> urinary tract

> > infections as well as rheumatoid arthritis twice as often as

men,

> while men

> > usually have higher levels of klebsiella and three times more

> ankylosing

> > spondylitis than women.

> >

> > In addition microbial overgrowth dam ages the intestinal wall

so

> that only

> > partly digested food particles can pass into the bloodstream,

> causing

> > allergies. In this way all auto-immune diseases can be linked

to

> food

> > allergies.

> >

> > While rheumatoid arthritis is a frequent feature of the

antibiotic

> syndrome,

> > and I regard it as relatively easy to cure, not many sufferers

of

> this

> > disease seem to be interested in this natural approach. The

other

> day a

> > young man with severe rheumatoid arthritis knocked at my door

to

> collect

> > money for a medically sponsored walkathon. When I told him

that I

> do not

> > give money for drug treatment as it can be overcome with

natural

> therapies,

> > he shouted: 'You are mad!' and left visibly upset.

> >

> > Other auto-immune diseases that have so far been linked to

> dysbiosis are

> > psoriasis, lupus erythematosus and pancreatitis. When remedies

are

> given

> > that bind bacterial endotoxins, these conditions usually

improve.

> A further

> > consequence of dysbiosis is susceptibility to food poisoning as

> with

> > salmonella bacteria, while a healthy intestinal flora prevents

> these from

> > multiplying and causing trouble.

> >

> > Staphylococcus aureus or golden staph cause serious infections

in

> hospital

> > patients. It has been found that not only golden staph but also

> other

> > infections are greatly potentised when they occur with a

Candida

> overgrowth.

> > As Candida overgrowth is a natural outcome of the standard

hospital

> > treatment, it is easy to see why golden staph is so deadly in

> hospitals.

> >

> > A similar picture emerges with AIDS. People do not die from the

> AIDS virus

> > but from Candida-potentised bacterial infections. I also see

the

> > antibiotic-induced dysbiosis in babies and infants as the main

> cause of

> > their frequent infections, glue ear and greatly contributing to

> cot death.

> >

> > While it used to be uncommon for children to have more than

one or

> two

> > infections a year, now more than six is the norm.

> >

> > In the 1940's Candida was found in only three per cent of

> autopsies, now the

> > figure is nearer thirty per cent. There are, of course, other

> factors that

> > can cause dysbiosis - the contraceptive pill, steroids and

other

> drugs,

> > radiation treatment and chemotherapy - but the main culprit is,

> without

> > doubt, antibiotics.

> >

> > Closely related to Candida are the mycoplasms or pleomorphic

> organisms.

> > These have been shown to be a main factor in the causation of

> cancer.

> > Therefore, antifungal therapy has also major benefits in cancer

> treatment.

> >

> > Dr Orian Truss

> >

> > [infections] J - guts

> >

> >

> > Do you support your gut-symbiosis emphasis mostly from

observing

> the

> > circumstances/course of human illness as reported in patient

> > testimony online?

> >

> > Have you seen this one?

> >

> >

> >

> > Arthritis Rheum. 2000 Nov;43(11):2583-9. Related Articles,

Links

> >

> > Oral antibiotics as a novel therapy for arthritis: evidence

for a

> > beneficial effect of intestinal Escherichia coli.

> >

> > Nieuwenhuis EE, Visser MR, Kavelaars A, Cobelens PM, Fleer A,

> Harmsen

> > W, Verhoef J, Akkermans LM, Heijnen CJ.

> >

> > Wilhelmina Children's Hospital, Utrecht, The Netherlands.

> >

> > OBJECTIVE: The intestinal flora is thought to play an

important

> role

> > in regulation of immune responses. We investigated the

effects of

> > changing the intestinal flora on the course of adjuvant-

induced

> > arthritis (AIA) and on experimental autoimmune

encephalomyelitis

> > (EAE) by the use of oral antibiotics. METHODS: Oral treatment

> with

> > either vancomycin or vancomycin, tobramycin, and colistin was

> started

> > after AIA and EAE induction. Clinical symptoms of AIA and EAE

> were

> > monitored, and microbial analysis of ileal samples was

performed.

> > RESULTS: Oral vancomycin treatment after disease induction

> > significantly decreased clinical symptoms of AIA.

Simultaneously,

> > increased concentrations of Escherichia coli were detected

in the

> > distal ileum of vancomycin-treated rats. Ileal

concentrations of

> E

> > coli were inversely related to disease scores in rats with

AIA.

> > Coadministration of colistin/tobramycin to prevent the

increase

> in E

> > coli abrogated the beneficial effect of vancomycin on AIA.

> Vancomycin

> > treatment also reduced the clinical symptoms of EAE.

CONCLUSION:

> We

> > propose oral vancomycin as a novel therapeutic strategy in

> autoimmune

> > diseases.

> >

> > PMID: 11083284 [PubMed - indexed for MEDLINE]

> >

> >

> >

> >

> >

> >

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I think going on my experiences that the gut is very resilient..the cells of the gut lining are replaced every two weeks or so if memory serves. I have come back from what I thought was permanent damage! I have been so ill I thought that recovery was impossible ..IB to the point of emergency surgery ...As I type this I am virtually symptom free ..although that will change come the next flare cycle.

What I see is that vanco is effective against the cell wall of gram pos bacteria ..spiro's are gram positive ... & there's the groups of researches who shout ..watch these gut spiro's that everone thinks are just there for the ride We reckon it may be possible they could go systemic & become a serious infection ..But they don't know about dysbiosis ..don't know about endemic Candida infections so they don't make the link!! But we can . ..The role of gut flora has been dubbed the black hole of medicine , almost nothing is known of how we need & interact with our gut flora .How do the docs respond to this fact, they stick their heads firmly in the sand every time the subject is aired & we suffer....It's clear to me that a cure is impossible while a dysbiosis exists it is should be the primary target of any therapy ..

[infections] J - guts> >> >> > Do you support your gut-symbiosis emphasis mostly from observing> the> > circumstances/course of human illness as reported in patient> > testimony online?> >> > Have you seen this one?> >> >> >> > Arthritis Rheum. 2000 Nov;43(11):2583-9. Related Articles, Links> >> > Oral antibiotics as a novel therapy for arthritis: evidence for a> > beneficial effect of intestinal Escherichia coli.> >> > Nieuwenhuis EE, Visser MR, Kavelaars A, Cobelens PM, Fleer A,> Harmsen> > W, Verhoef J, Akkermans LM, Heijnen CJ.> >> > Wilhelmina Children's Hospital, Utrecht, The Netherlands.> >> > OBJECTIVE: The intestinal flora is thought to play an important> role> > in regulation of immune responses. We investigated the effects of> > changing the intestinal flora on the course of adjuvant-induced> > arthritis (AIA) and on experimental autoimmune encephalomyelitis> > (EAE) by the use of oral antibiotics. METHODS: Oral treatment> with> > either vancomycin or vancomycin, tobramycin, and colistin was> started> > after AIA and EAE induction. Clinical symptoms of AIA and EAE> were> > monitored, and microbial analysis of ileal samples was performed.> > RESULTS: Oral vancomycin treatment after disease induction> > significantly decreased clinical symptoms of AIA. Simultaneously,> > increased concentrations of Escherichia coli were detected in the> > distal ileum of vancomycin-treated rats. Ileal concentrations of> E> > coli were inversely related to disease scores in rats with AIA.> > Coadministration of colistin/tobramycin to prevent the increase> in E> > coli abrogated the beneficial effect of vancomycin on AIA.> Vancomycin> > treatment also reduced the clinical symptoms of EAE. CONCLUSION:> We> > propose oral vancomycin as a novel therapeutic strategy in> autoimmune> > diseases.> >> > PMID: 11083284 [PubMed - indexed for MEDLINE]> >> >> >> >> >> >

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I feel the cycle of suffering a gut toxin attack may leave quite a

bit of toxin in the fat cells as well- which can also possably

recirculate?

> > > All sources , The more crucial core information came

from

> > specialist

> > > docs Truss, Cranton , & Crook ...but I have built a

knowledge

> base

> > from

> > > patient testimony's and looking at the overall picture

with gut

> > dysbiosis in

> > > mind.....I have found nothing to lead me to think

> otherwise ...I

> > have

> > > corresponded in the not too distant past with doctors who

> before

> > me had no

> > > experience with yeast & dysbiosis... they now treat

> routinely ..I

> > do meet

> > > people who are obviously ill with a yeast

infection ..Little

> > story...

> > > Just a few weeks ago I was telling the tale of endemic

yeast

> to a

> > friend I

> > > see at the local pub...My wife's got that, he said .So next

> > meeting his wife

> > > came along with him , I gave her the full story ....Judy

[his

> > wife ] took

> > > matters into her own hands and found a lab [near

Cambridge?]

> took

> > the

> > > antibody tests, and guess what, all three came up

positive ...

> Off

> > to her GP

> > > with the advice from the lab to seek " immediate medical

> > attention " ...Her GP

> > > was impressed ,but wanted a few opinions on how to

> treat ..Gave

> > Judy a

> > > further appointment , where treatment she understood would

be

> > > instigated...But it wasn't ...Judy was practically thrown

out

> of

> > the

> > > practice ...Yeast treatment UK style...I am now teaching

her

> the

> > arts of

> > > self-treating ...

> > >

> > > I'll just take the opportunity to trot this very telling

> article

> > out ...You

> > > better believe it, as they say & thanks for the

> extract ..what a

> > strange

> > > set of results ,just shows how intertwined & symbiotic our

gut

> > flora is

> > > ...

> > >

> > > Article by Dr Truss… In 1953 Dr Orian Truss discovered the

> > devastating

> > > effects of antibiotics in Alabama (USA)

> > >

> > > Lack of energy and digestive disturbances, arthritic joint

> pains,

> > skin

> > > disease, menstrual problems, emotional instability and

> depression.

> > All

> > > symptoms of what I call the 'antibiotic syndrome' which

have

> > greatly

> > > increased in frequency in recent years.

> > >

> > > On further examination, more symptoms may be discovered.

Most

> of

> > the

> > > gastro-intestinal tract is tender when pressed, especially

the

> > small

> > > intestine, liver and gall bladder. There may even have

been a

> gall

> > bladder

> > > operation that failed to improve the condition, sometimes

even

> > worsening the

> > > symptoms.

> > >

> > > There could be a history of thrush or oral, anal or vaginal

> > itching. When

> > > these are present the diagnosis of Candida is obvious but

it

> may

> > also be

> > > present in the absence of these manifestations and that

can be

> > somewhat

> > > confusing. The yeast or fungus Candida albicans, of course,

> > thrives during

> > > antibiotic treatment. I regard it as reckless negligence to

> > prescribe

> > > antibiotics without simultaneous fungicides and replacement

> > therapy with

> > > lactobacilli afterwards. I believe that this practice has

> greatly

> > added to

> > > our vast pool of a chronically sick population.

> > >

> > > However, the 'antibiotic syndrome' is not just due to

Candida.

> I

> > regard it

> > > more generally as a 'dysbiosis' where the wrong kind of

> microbes

> > inhabit the

> > > intestinal tract, not just Candida and other fungi, but

many

> types

> > of

> > > pathogenic bacteria including coli bacteria which are

normal in

> > the colon

> > > but become disease-forming when they ascend into the small

> > intestine.

> > >

> > > If the problem has existed for years, there is usually a

lack

> of

> > gastric

> > > acid which then allows the stomach to be colonised by

microbes,

> > causing

> > > inflammation with pain and later, ulcers. The toxins

released

> by

> > the

> > > microbial overpopulation cause in addition chronic

> inflammation of

> > the

> > > liver, gall bladder, pancreas and intestines. I regard it

as

> > rather likely

> > > that a chronic inflammation of the pancreas is a major

> > contributing factor

> > > in the development of insulin-dependent diabetes.

> > >

> > > Bacterial attack

> > >

> > > Specific types of pathogenic bacteria appear to cause or

> > contribute to

> > > specific auto-immune diseases. One variety of coli

bacteria,

> for

> > instance,

> > > produces a molecule that is very similar to insulin. When

the

> > immune system

> > > becomes activated against this molecule it may then also

attack

> > related

> > > features at the beta cells of the pancreas

> > >

> > > Another type of bacteria, Yersinia enterocolitica, induces

an

> > immune

> > > response that attacks the thyroid gland and leads to

Grave's

> > disease with a

> > > serious overproduction of thyroid hormones.

> > >

> > > Ulcerative colitis is linked to overgrowth with pathogenic

> > microbes, the

> > > same as Crohn's disease, osteoporosis and ankylosing

> spondylitis.

> > In

> > > ankylosing spondylitis the vertebra of the spine fuse

together

> > causing

> > > stiffness and pain. Other joints may in time become

affected.

> > >

> > > Klebsiella, another type of pathogenic bacteria, produces a

> > molecule that is

> > > similar to a tissue type found in people with this disease.

> When

> > klebsiella

> > > numbers in the gut decrease, related antibodies in the

blood

> > decrease and

> > > the condition improves.

> > >

> > > Rheumatoid arthritis is linked to other bacteria, called

> proteus.

> > Proteus is

> > > also a common cause of urinary tract infections. Women

suffer

> > urinary tract

> > > infections as well as rheumatoid arthritis twice as often

as

> men,

> > while men

> > > usually have higher levels of klebsiella and three times

more

> > ankylosing

> > > spondylitis than women.

> > >

> > > In addition microbial overgrowth dam ages the intestinal

wall

> so

> > that only

> > > partly digested food particles can pass into the

bloodstream,

> > causing

> > > allergies. In this way all auto-immune diseases can be

linked

> to

> > food

> > > allergies.

> > >

> > > While rheumatoid arthritis is a frequent feature of the

> antibiotic

> > syndrome,

> > > and I regard it as relatively easy to cure, not many

sufferers

> of

> > this

> > > disease seem to be interested in this natural approach. The

> other

> > day a

> > > young man with severe rheumatoid arthritis knocked at my

door

> to

> > collect

> > > money for a medically sponsored walkathon. When I told him

> that I

> > do not

> > > give money for drug treatment as it can be overcome with

> natural

> > therapies,

> > > he shouted: 'You are mad!' and left visibly upset.

> > >

> > > Other auto-immune diseases that have so far been linked to

> > dysbiosis are

> > > psoriasis, lupus erythematosus and pancreatitis. When

remedies

> are

> > given

> > > that bind bacterial endotoxins, these conditions usually

> improve.

> > A further

> > > consequence of dysbiosis is susceptibility to food

poisoning as

> > with

> > > salmonella bacteria, while a healthy intestinal flora

prevents

> > these from

> > > multiplying and causing trouble.

> > >

> > > Staphylococcus aureus or golden staph cause serious

infections

> in

> > hospital

> > > patients. It has been found that not only golden staph but

also

> > other

> > > infections are greatly potentised when they occur with a

> Candida

> > overgrowth.

> > > As Candida overgrowth is a natural outcome of the standard

> hospital

> > > treatment, it is easy to see why golden staph is so deadly

in

> > hospitals.

> > >

> > > A similar picture emerges with AIDS. People do not die

from the

> > AIDS virus

> > > but from Candida-potentised bacterial infections. I also

see

> the

> > > antibiotic-induced dysbiosis in babies and infants as the

main

> > cause of

> > > their frequent infections, glue ear and greatly

contributing to

> > cot death.

> > >

> > > While it used to be uncommon for children to have more than

> one or

> > two

> > > infections a year, now more than six is the norm.

> > >

> > > In the 1940's Candida was found in only three per cent of

> > autopsies, now the

> > > figure is nearer thirty per cent. There are, of course,

other

> > factors that

> > > can cause dysbiosis - the contraceptive pill, steroids and

> other

> > drugs,

> > > radiation treatment and chemotherapy - but the main

culprit is,

> > without

> > > doubt, antibiotics.

> > >

> > > Closely related to Candida are the mycoplasms or

pleomorphic

> > organisms.

> > > These have been shown to be a main factor in the causation

of

> > cancer.

> > > Therefore, antifungal therapy has also major benefits in

cancer

> > treatment.

> > >

> > > Dr Orian Truss

> > >

> > > [infections] J - guts

> > >

> > >

> > > Do you support your gut-symbiosis emphasis mostly from

> observing

> > the

> > > circumstances/course of human illness as reported in

patient

> > > testimony online?

> > >

> > > Have you seen this one?

> > >

> > >

> > >

> > > Arthritis Rheum. 2000 Nov;43(11):2583-9. Related

Articles,

> Links

> > >

> > > Oral antibiotics as a novel therapy for arthritis:

evidence

> for a

> > > beneficial effect of intestinal Escherichia coli.

> > >

> > > Nieuwenhuis EE, Visser MR, Kavelaars A, Cobelens PM,

Fleer A,

> > Harmsen

> > > W, Verhoef J, Akkermans LM, Heijnen CJ.

> > >

> > > Wilhelmina Children's Hospital, Utrecht, The Netherlands.

> > >

> > > OBJECTIVE: The intestinal flora is thought to play an

> important

> > role

> > > in regulation of immune responses. We investigated the

> effects of

> > > changing the intestinal flora on the course of adjuvant-

> induced

> > > arthritis (AIA) and on experimental autoimmune

> encephalomyelitis

> > > (EAE) by the use of oral antibiotics. METHODS: Oral

treatment

> > with

> > > either vancomycin or vancomycin, tobramycin, and

colistin was

> > started

> > > after AIA and EAE induction. Clinical symptoms of AIA

and EAE

> > were

> > > monitored, and microbial analysis of ileal samples was

> performed.

> > > RESULTS: Oral vancomycin treatment after disease

induction

> > > significantly decreased clinical symptoms of AIA.

> Simultaneously,

> > > increased concentrations of Escherichia coli were

detected

> in the

> > > distal ileum of vancomycin-treated rats. Ileal

> concentrations of

> > E

> > > coli were inversely related to disease scores in rats

with

> AIA.

> > > Coadministration of colistin/tobramycin to prevent the

> increase

> > in E

> > > coli abrogated the beneficial effect of vancomycin on

AIA.

> > Vancomycin

> > > treatment also reduced the clinical symptoms of EAE.

> CONCLUSION:

> > We

> > > propose oral vancomycin as a novel therapeutic strategy

in

> > autoimmune

> > > diseases.

> > >

> > > PMID: 11083284 [PubMed - indexed for MEDLINE]

> > >

> > >

> > >

> > >

> > >

> > >

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Tony, i was thinking more about Dr Andy a leading CFS expert here in the UK who reports he finds spirochetes in every patient suffering with chronic fatigue…

On the the cyclical nature of our illness . The bacteria waxes and wanes on a cycle, Dr reports two growth spurts per

month – about 8/9 days and 30 days – Dr ’s microscopy experience tells us one day it can be real difficult to see any bacteria but a few days

later the blood is teeming with them..

[infections] J - guts> > >> > >> > > Do you support your gut-symbiosis emphasis mostly from> observing> > the> > > circumstances/course of human illness as reported in patient> > > testimony online?> > >> > > Have you seen this one?> > >> > >> > >> > > Arthritis Rheum. 2000 Nov;43(11):2583-9. Related Articles,> Links> > >> > > Oral antibiotics as a novel therapy for arthritis: evidence> for a> > > beneficial effect of intestinal Escherichia coli.> > >> > > Nieuwenhuis EE, Visser MR, Kavelaars A, Cobelens PM, Fleer A,> > Harmsen> > > W, Verhoef J, Akkermans LM, Heijnen CJ.> > >> > > Wilhelmina Children's Hospital, Utrecht, The Netherlands.> > >> > > OBJECTIVE: The intestinal flora is thought to play an> important> > role> > > in regulation of immune responses. We investigated the> effects of> > > changing the intestinal flora on the course of adjuvant-> induced> > > arthritis (AIA) and on experimental autoimmune> encephalomyelitis> > > (EAE) by the use of oral antibiotics. METHODS: Oral treatment> > with> > > either vancomycin or vancomycin, tobramycin, and colistin was> > started> > > after AIA and EAE induction. Clinical symptoms of AIA and EAE> > were> > > monitored, and microbial analysis of ileal samples was> performed.> > > RESULTS: Oral vancomycin treatment after disease induction> > > significantly decreased clinical symptoms of AIA.> Simultaneously,> > > increased concentrations of Escherichia coli were detected> in the> > > distal ileum of vancomycin-treated rats. Ileal> concentrations of> > E> > > coli were inversely related to disease scores in rats with> AIA.> > > Coadministration of colistin/tobramycin to prevent the> increase> > in E> > > coli abrogated the beneficial effect of vancomycin on AIA.> > Vancomycin> > > treatment also reduced the clinical symptoms of EAE.> CONCLUSION:> > We> > > propose oral vancomycin as a novel therapeutic strategy in> > autoimmune> > > diseases.> > >> > > PMID: 11083284 [PubMed - indexed for MEDLINE]> > >> > >> > >> > >> > >> > >

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Dr. better get his ass in to gear and show the world his

science and how clear it is.My good friend from england was working

close to Dr. and he even had an incubator with plates to

check for blood born bacteria for Dr. .Our friendship got us

both doing microbiology at the same time, unfortuantely he couldn't

get a foot in the door at the lab as I did and his interests were

cut short without that support system. His finding is similar to

today's post on blood born pathogen's, the not sick group that I pay

close attention to at my local supermarket, I feel is waiting to

keel over.I think blood bacteria is very common, just because people

still function it doesn't mean there not scik, they are being worn

down in my observations.The big thing not to overlook is size. I

know what he see's stemming from blood cells look like spirochetes

but on initial observation I say he is wrong. His second video

showing spirochetes is correct.Dr. is in a comfortable

position to show much clearer his science, and this should leave no

doubt to the scientists in particular the microbiologists that he

has his cfser's all showing positive for Bb.This is not so clear at

this point. I also pay close attention to what drugs people respond

to and they are mainly gram positive drugs, which makes this still

a little cloudy.

tony

> > > > All sources , The more crucial core information

came

> from

> > > specialist

> > > > docs Truss, Cranton , & Crook ...but I have built a

> knowledge

> > base

> > > from

> > > > patient testimony's and looking at the overall picture

> with gut

> > > dysbiosis in

> > > > mind.....I have found nothing to lead me to think

> > otherwise ...I

> > > have

> > > > corresponded in the not too distant past with doctors

who

> > before

> > > me had no

> > > > experience with yeast & dysbiosis... they now treat

> > routinely ..I

> > > do meet

> > > > people who are obviously ill with a yeast

> infection ..Little

> > > story...

> > > > Just a few weeks ago I was telling the tale of endemic

> yeast

> > to a

> > > friend I

> > > > see at the local pub...My wife's got that, he said .So

next

> > > meeting his wife

> > > > came along with him , I gave her the full

story ....Judy

> [his

> > > wife ] took

> > > > matters into her own hands and found a lab [near

> Cambridge?]

> > took

> > > the

> > > > antibody tests, and guess what, all three came up

> positive ...

> > Off

> > > to her GP

> > > > with the advice from the lab to seek " immediate medical

> > > attention " ...Her GP

> > > > was impressed ,but wanted a few opinions on how to

> > treat ..Gave

> > > Judy a

> > > > further appointment , where treatment she understood

would

> be

> > > > instigated...But it wasn't ...Judy was practically

thrown

> out

> > of

> > > the

> > > > practice ...Yeast treatment UK style...I am now

teaching

> her

> > the

> > > arts of

> > > > self-treating ...

> > > >

> > > > I'll just take the opportunity to trot this very

telling

> > article

> > > out ...You

> > > > better believe it, as they say & thanks for the

> > extract ..what a

> > > strange

> > > > set of results ,just shows how intertwined & symbiotic

our

> gut

> > > flora is

> > > > ...

> > > >

> > > > Article by Dr Truss… In 1953 Dr Orian Truss discovered

the

> > > devastating

> > > > effects of antibiotics in Alabama (USA)

> > > >

> > > > Lack of energy and digestive disturbances, arthritic

joint

> > pains,

> > > skin

> > > > disease, menstrual problems, emotional instability and

> > depression.

> > > All

> > > > symptoms of what I call the 'antibiotic syndrome' which

> have

> > > greatly

> > > > increased in frequency in recent years.

> > > >

> > > > On further examination, more symptoms may be

discovered.

> Most

> > of

> > > the

> > > > gastro-intestinal tract is tender when pressed,

especially

> the

> > > small

> > > > intestine, liver and gall bladder. There may even have

> been a

> > gall

> > > bladder

> > > > operation that failed to improve the condition,

sometimes

> even

> > > worsening the

> > > > symptoms.

> > > >

> > > > There could be a history of thrush or oral, anal or

vaginal

> > > itching. When

> > > > these are present the diagnosis of Candida is obvious

but

> it

> > may

> > > also be

> > > > present in the absence of these manifestations and that

> can be

> > > somewhat

> > > > confusing. The yeast or fungus Candida albicans, of

course,

> > > thrives during

> > > > antibiotic treatment. I regard it as reckless

negligence to

> > > prescribe

> > > > antibiotics without simultaneous fungicides and

replacement

> > > therapy with

> > > > lactobacilli afterwards. I believe that this practice

has

> > greatly

> > > added to

> > > > our vast pool of a chronically sick population.

> > > >

> > > > However, the 'antibiotic syndrome' is not just due to

> Candida.

> > I

> > > regard it

> > > > more generally as a 'dysbiosis' where the wrong kind of

> > microbes

> > > inhabit the

> > > > intestinal tract, not just Candida and other fungi, but

> many

> > types

> > > of

> > > > pathogenic bacteria including coli bacteria which are

> normal in

> > > the colon

> > > > but become disease-forming when they ascend into the

small

> > > intestine.

> > > >

> > > > If the problem has existed for years, there is usually

a

> lack

> > of

> > > gastric

> > > > acid which then allows the stomach to be colonised by

> microbes,

> > > causing

> > > > inflammation with pain and later, ulcers. The toxins

> released

> > by

> > > the

> > > > microbial overpopulation cause in addition chronic

> > inflammation of

> > > the

> > > > liver, gall bladder, pancreas and intestines. I regard

it

> as

> > > rather likely

> > > > that a chronic inflammation of the pancreas is a major

> > > contributing factor

> > > > in the development of insulin-dependent diabetes.

> > > >

> > > > Bacterial attack

> > > >

> > > > Specific types of pathogenic bacteria appear to cause

or

> > > contribute to

> > > > specific auto-immune diseases. One variety of coli

> bacteria,

> > for

> > > instance,

> > > > produces a molecule that is very similar to insulin.

When

> the

> > > immune system

> > > > becomes activated against this molecule it may then

also

> attack

> > > related

> > > > features at the beta cells of the pancreas

> > > >

> > > > Another type of bacteria, Yersinia enterocolitica,

induces

> an

> > > immune

> > > > response that attacks the thyroid gland and leads to

> Grave's

> > > disease with a

> > > > serious overproduction of thyroid hormones.

> > > >

> > > > Ulcerative colitis is linked to overgrowth with

pathogenic

> > > microbes, the

> > > > same as Crohn's disease, osteoporosis and ankylosing

> > spondylitis.

> > > In

> > > > ankylosing spondylitis the vertebra of the spine fuse

> together

> > > causing

> > > > stiffness and pain. Other joints may in time become

> affected.

> > > >

> > > > Klebsiella, another type of pathogenic bacteria,

produces a

> > > molecule that is

> > > > similar to a tissue type found in people with this

disease.

> > When

> > > klebsiella

> > > > numbers in the gut decrease, related antibodies in the

> blood

> > > decrease and

> > > > the condition improves.

> > > >

> > > > Rheumatoid arthritis is linked to other bacteria,

called

> > proteus.

> > > Proteus is

> > > > also a common cause of urinary tract infections. Women

> suffer

> > > urinary tract

> > > > infections as well as rheumatoid arthritis twice as

often

> as

> > men,

> > > while men

> > > > usually have higher levels of klebsiella and three

times

> more

> > > ankylosing

> > > > spondylitis than women.

> > > >

> > > > In addition microbial overgrowth dam ages the

intestinal

> wall

> > so

> > > that only

> > > > partly digested food particles can pass into the

> bloodstream,

> > > causing

> > > > allergies. In this way all auto-immune diseases can be

> linked

> > to

> > > food

> > > > allergies.

> > > >

> > > > While rheumatoid arthritis is a frequent feature of the

> > antibiotic

> > > syndrome,

> > > > and I regard it as relatively easy to cure, not many

> sufferers

> > of

> > > this

> > > > disease seem to be interested in this natural

approach. The

> > other

> > > day a

> > > > young man with severe rheumatoid arthritis knocked at

my

> door

> > to

> > > collect

> > > > money for a medically sponsored walkathon. When I told

him

> > that I

> > > do not

> > > > give money for drug treatment as it can be overcome

with

> > natural

> > > therapies,

> > > > he shouted: 'You are mad!' and left visibly upset.

> > > >

> > > > Other auto-immune diseases that have so far been

linked to

> > > dysbiosis are

> > > > psoriasis, lupus erythematosus and pancreatitis. When

> remedies

> > are

> > > given

> > > > that bind bacterial endotoxins, these conditions

usually

> > improve.

> > > A further

> > > > consequence of dysbiosis is susceptibility to food

> poisoning as

> > > with

> > > > salmonella bacteria, while a healthy intestinal flora

> prevents

> > > these from

> > > > multiplying and causing trouble.

> > > >

> > > > Staphylococcus aureus or golden staph cause serious

> infections

> > in

> > > hospital

> > > > patients. It has been found that not only golden staph

but

> also

> > > other

> > > > infections are greatly potentised when they occur with

a

> > Candida

> > > overgrowth.

> > > > As Candida overgrowth is a natural outcome of the

standard

> > hospital

> > > > treatment, it is easy to see why golden staph is so

deadly

> in

> > > hospitals.

> > > >

> > > > A similar picture emerges with AIDS. People do not die

> from the

> > > AIDS virus

> > > > but from Candida-potentised bacterial infections. I

also

> see

> > the

> > > > antibiotic-induced dysbiosis in babies and infants as

the

> main

> > > cause of

> > > > their frequent infections, glue ear and greatly

> contributing to

> > > cot death.

> > > >

> > > > While it used to be uncommon for children to have more

than

> > one or

> > > two

> > > > infections a year, now more than six is the norm.

> > > >

> > > > In the 1940's Candida was found in only three per cent

of

> > > autopsies, now the

> > > > figure is nearer thirty per cent. There are, of course,

> other

> > > factors that

> > > > can cause dysbiosis - the contraceptive pill, steroids

and

> > other

> > > drugs,

> > > > radiation treatment and chemotherapy - but the main

> culprit is,

> > > without

> > > > doubt, antibiotics.

> > > >

> > > > Closely related to Candida are the mycoplasms or

> pleomorphic

> > > organisms.

> > > > These have been shown to be a main factor in the

causation

> of

> > > cancer.

> > > > Therefore, antifungal therapy has also major benefits

in

> cancer

> > > treatment.

> > > >

> > > > Dr Orian Truss

> > > >

> > > > [infections] J - guts

> > > >

> > > >

> > > > Do you support your gut-symbiosis emphasis mostly

from

> > observing

> > > the

> > > > circumstances/course of human illness as reported in

> patient

> > > > testimony online?

> > > >

> > > > Have you seen this one?

> > > >

> > > >

> > > >

> > > > Arthritis Rheum. 2000 Nov;43(11):2583-9. Related

> Articles,

> > Links

> > > >

> > > > Oral antibiotics as a novel therapy for arthritis:

> evidence

> > for a

> > > > beneficial effect of intestinal Escherichia coli.

> > > >

> > > > Nieuwenhuis EE, Visser MR, Kavelaars A, Cobelens PM,

> Fleer A,

> > > Harmsen

> > > > W, Verhoef J, Akkermans LM, Heijnen CJ.

> > > >

> > > > Wilhelmina Children's Hospital, Utrecht, The

Netherlands.

> > > >

> > > > OBJECTIVE: The intestinal flora is thought to play an

> > important

> > > role

> > > > in regulation of immune responses. We investigated

the

> > effects of

> > > > changing the intestinal flora on the course of

adjuvant-

> > induced

> > > > arthritis (AIA) and on experimental autoimmune

> > encephalomyelitis

> > > > (EAE) by the use of oral antibiotics. METHODS: Oral

> treatment

> > > with

> > > > either vancomycin or vancomycin, tobramycin, and

> colistin was

> > > started

> > > > after AIA and EAE induction. Clinical symptoms of AIA

> and EAE

> > > were

> > > > monitored, and microbial analysis of ileal samples

was

> > performed.

> > > > RESULTS: Oral vancomycin treatment after disease

> induction

> > > > significantly decreased clinical symptoms of AIA.

> > Simultaneously,

> > > > increased concentrations of Escherichia coli were

> detected

> > in the

> > > > distal ileum of vancomycin-treated rats. Ileal

> > concentrations of

> > > E

> > > > coli were inversely related to disease scores in rats

> with

> > AIA.

> > > > Coadministration of colistin/tobramycin to prevent

the

> > increase

> > > in E

> > > > coli abrogated the beneficial effect of vancomycin on

> AIA.

> > > Vancomycin

> > > > treatment also reduced the clinical symptoms of EAE.

> > CONCLUSION:

> > > We

> > > > propose oral vancomycin as a novel therapeutic

strategy

> in

> > > autoimmune

> > > > diseases.

> > > >

> > > > PMID: 11083284 [PubMed - indexed for MEDLINE]

> > > >

> > > >

> > > >

> > > >

> > > >

> > > >

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Tony, one of my criticisms of you in the past is your authoritive announcements of your findings…Fact is interpreting what you see under a microscope is a very in-depth hard learned skill …your findings are interesting ,but in no way could be thought of as definitive .. Herxing is the reaction to the die off of pathogens, usually confined to a brief period following the onset of ABX treatment…I experience a flare cycle in line with Dr s findings ,it’s puzzled me for years, Dr W finds the blood teeming with…??.. one day & not another, He’s on record with that , it’s an easily repeatable easily checkable test , I don’t think he would risk his reputation making the results up! .And don’t forget he’s infected too., number one guinea pig… I can predict a flare [now moved to one week before the full moon] So not a Herx…compelling evidence, I think so .Though I do agree I wish Dr W would get his finger out & publish , I don’t know why he doesn’t ..Your description of a darkfield as a alternative thing is surprising not to mention incorrect, it’s a recognised research tool ..see below ..Sorry Tony , but stop shooting from the hip…

Ned Tijdschr Tandheelkd. 1992 Oct;99(10):381-4.

Related Articles,

Links [Darkfield or phase contrast microscopy. Usefulness in periodontology][Article in Dutch]Callens A.Uit de Eenheid Parodontologie van de Faculteit Geneeskunde te Leuven, Belgie.Microscopic evaluation of a dental plaque sample is not very useful, since the bacteria are difficult to distinguish from the diluent (same refractive index). Two types of microscopic analyses try to solve this problem in a different way. Using a darkfield microscope, the object is illuminated by slanting rays of light, that are then dispersed or bent away and enter the object. In this way, a shining image on a dark background is formed. The phase contrast microscope uses two principles of the geometry (wave length and amplitude) to create an image of the illuminated cells. Methodologically the next aspects are important, since they strongly influence the outcome of the analysis: contamination of the sample, technique of sampling and preparation of the sample. The reproducibility of the above mentioned techniques is high when a great number of parameters is kept constant. The analysis of the sample give us some clinically relevant information.

[infections] J - guts> > > >> > > >> > > > Do you support your gut-symbiosis emphasis mostly from> > observing> > > the> > > > circumstances/course of human illness as reported in> patient> > > > testimony online?> > > >> > > > Have you seen this one?> > > >> > > >> > > >> > > > Arthritis Rheum. 2000 Nov;43(11):2583-9. Related> Articles,> > Links> > > >> > > > Oral antibiotics as a novel therapy for arthritis:> evidence> > for a> > > > beneficial effect of intestinal Escherichia coli.> > > >> > > > Nieuwenhuis EE, Visser MR, Kavelaars A, Cobelens PM,> Fleer A,> > > Harmsen> > > > W, Verhoef J, Akkermans LM, Heijnen CJ.> > > >> > > > Wilhelmina Children's Hospital, Utrecht, The Netherlands.> > > >> > > > OBJECTIVE: The intestinal flora is thought to play an> > important> > > role> > > > in regulation of immune responses. We investigated the> > effects of> > > > changing the intestinal flora on the course of adjuvant-> > induced> > > > arthritis (AIA) and on experimental autoimmune> > encephalomyelitis> > > > (EAE) by the use of oral antibiotics. METHODS: Oral> treatment> > > with> > > > either vancomycin or vancomycin, tobramycin, and> colistin was> > > started> > > > after AIA and EAE induction. Clinical symptoms of AIA> and EAE> > > were> > > > monitored, and microbial analysis of ileal samples was> > performed.> > > > RESULTS: Oral vancomycin treatment after disease> induction> > > > significantly decreased clinical symptoms of AIA.> > Simultaneously,> > > > increased concentrations of Escherichia coli were> detected> > in the> > > > distal ileum of vancomycin-treated rats. Ileal> > concentrations of> > > E> > > > coli were inversely related to disease scores in rats> with> > AIA.> > > > Coadministration of colistin/tobramycin to prevent the> > increase> > > in E> > > > coli abrogated the beneficial effect of vancomycin on> AIA.> > > Vancomycin> > > > treatment also reduced the clinical symptoms of EAE.> > CONCLUSION:> > > We> > > > propose oral vancomycin as a novel therapeutic strategy> in> > > autoimmune> > > > diseases.> > > >> > > > PMID: 11083284 [PubMed - indexed for MEDLINE]> > > >> > > >> > > >> > > >> > > >> > > >

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Might explain the IBS cycle, too.

penny

" Jaep " <Jaep@L...> wrote:

> On the the cyclical nature of our illness . The bacteria waxes and

wanes on a cycle, Dr reports two growth spurts per month –

about 8/9 days and 30 days – Dr 's microscopy experience tells

> us one day it can be real difficult to see any bacteria but a few

days later the blood is teeming with them..

>

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I don't shoot from the hip. The fact that darkfield is being

discussed is misleading, the part of darkfield- live cell microscopy

got harsh treatment due to the 4 different events taking place

according to 4 differnet people in the same building. My friends lab

has over 16 microscopes (last time I bothered to get a rough

estimate) and many of those I strongly believe are set up darkfield

without any problem, also doctors can have scopes set up darkfield

it's that live cell microscopy story that everyone is up in the air

about.What you observe in the field of a microscope is a hard

learned skill for sure. Unfortuantely what you don't know is the

little events that are being interpreted in a sample.People have bad

red blood cells with autoimmune diseases,but the emphasis of regular

pathology is simple cell science. People aren't looking at your red

cells at 1000 X magnification they are just giving rough estimates

of observations at 400 x magnification.There's something happening

and no-ones really bothering to use any skills more often than

not,so to say these skills are hard learned is ignoring the

macdonalds approach that rules the roost in pathology.

> > > > > All sources , The more crucial core information

> came

> > from

> > > > specialist

> > > > > docs Truss, Cranton , & Crook ...but I have built a

> > knowledge

> > > base

> > > > from

> > > > > patient testimony's and looking at the overall

picture

> > with gut

> > > > dysbiosis in

> > > > > mind.....I have found nothing to lead me to think

> > > otherwise ...I

> > > > have

> > > > > corresponded in the not too distant past with

doctors

> who

> > > before

> > > > me had no

> > > > > experience with yeast & dysbiosis... they now treat

> > > routinely ..I

> > > > do meet

> > > > > people who are obviously ill with a yeast

> > infection ..Little

> > > > story...

> > > > > Just a few weeks ago I was telling the tale of

endemic

> > yeast

> > > to a

> > > > friend I

> > > > > see at the local pub...My wife's got that, he

said .So

> next

> > > > meeting his wife

> > > > > came along with him , I gave her the full

> story ....Judy

> > [his

> > > > wife ] took

> > > > > matters into her own hands and found a lab [near

> > Cambridge?]

> > > took

> > > > the

> > > > > antibody tests, and guess what, all three came up

> > positive ...

> > > Off

> > > > to her GP

> > > > > with the advice from the lab to seek " immediate

medical

> > > > attention " ...Her GP

> > > > > was impressed ,but wanted a few opinions on how to

> > > treat ..Gave

> > > > Judy a

> > > > > further appointment , where treatment she

understood

> would

> > be

> > > > > instigated...But it wasn't ...Judy was practically

> thrown

> > out

> > > of

> > > > the

> > > > > practice ...Yeast treatment UK style...I am now

> teaching

> > her

> > > the

> > > > arts of

> > > > > self-treating ...

> > > > >

> > > > > I'll just take the opportunity to trot this very

> telling

> > > article

> > > > out ...You

> > > > > better believe it, as they say & thanks for the

> > > extract ..what a

> > > > strange

> > > > > set of results ,just shows how intertwined &

symbiotic

> our

> > gut

> > > > flora is

> > > > > ...

> > > > >

> > > > > Article by Dr Truss… In 1953 Dr Orian Truss

discovered

> the

> > > > devastating

> > > > > effects of antibiotics in Alabama (USA)

> > > > >

> > > > > Lack of energy and digestive disturbances,

arthritic

> joint

> > > pains,

> > > > skin

> > > > > disease, menstrual problems, emotional instability

and

> > > depression.

> > > > All

> > > > > symptoms of what I call the 'antibiotic syndrome'

which

> > have

> > > > greatly

> > > > > increased in frequency in recent years.

> > > > >

> > > > > On further examination, more symptoms may be

> discovered.

> > Most

> > > of

> > > > the

> > > > > gastro-intestinal tract is tender when pressed,

> especially

> > the

> > > > small

> > > > > intestine, liver and gall bladder. There may even

have

> > been a

> > > gall

> > > > bladder

> > > > > operation that failed to improve the condition,

> sometimes

> > even

> > > > worsening the

> > > > > symptoms.

> > > > >

> > > > > There could be a history of thrush or oral, anal or

> vaginal

> > > > itching. When

> > > > > these are present the diagnosis of Candida is

obvious

> but

> > it

> > > may

> > > > also be

> > > > > present in the absence of these manifestations and

that

> > can be

> > > > somewhat

> > > > > confusing. The yeast or fungus Candida albicans, of

> course,

> > > > thrives during

> > > > > antibiotic treatment. I regard it as reckless

> negligence to

> > > > prescribe

> > > > > antibiotics without simultaneous fungicides and

> replacement

> > > > therapy with

> > > > > lactobacilli afterwards. I believe that this

practice

> has

> > > greatly

> > > > added to

> > > > > our vast pool of a chronically sick population.

> > > > >

> > > > > However, the 'antibiotic syndrome' is not just due

to

> > Candida.

> > > I

> > > > regard it

> > > > > more generally as a 'dysbiosis' where the wrong

kind of

> > > microbes

> > > > inhabit the

> > > > > intestinal tract, not just Candida and other

fungi, but

> > many

> > > types

> > > > of

> > > > > pathogenic bacteria including coli bacteria which

are

> > normal in

> > > > the colon

> > > > > but become disease-forming when they ascend into

the

> small

> > > > intestine.

> > > > >

> > > > > If the problem has existed for years, there is

usually

> a

> > lack

> > > of

> > > > gastric

> > > > > acid which then allows the stomach to be colonised

by

> > microbes,

> > > > causing

> > > > > inflammation with pain and later, ulcers. The

toxins

> > released

> > > by

> > > > the

> > > > > microbial overpopulation cause in addition chronic

> > > inflammation of

> > > > the

> > > > > liver, gall bladder, pancreas and intestines. I

regard

> it

> > as

> > > > rather likely

> > > > > that a chronic inflammation of the pancreas is a

major

> > > > contributing factor

> > > > > in the development of insulin-dependent diabetes.

> > > > >

> > > > > Bacterial attack

> > > > >

> > > > > Specific types of pathogenic bacteria appear to

cause

> or

> > > > contribute to

> > > > > specific auto-immune diseases. One variety of coli

> > bacteria,

> > > for

> > > > instance,

> > > > > produces a molecule that is very similar to

insulin.

> When

> > the

> > > > immune system

> > > > > becomes activated against this molecule it may then

> also

> > attack

> > > > related

> > > > > features at the beta cells of the pancreas

> > > > >

> > > > > Another type of bacteria, Yersinia enterocolitica,

> induces

> > an

> > > > immune

> > > > > response that attacks the thyroid gland and leads

to

> > Grave's

> > > > disease with a

> > > > > serious overproduction of thyroid hormones.

> > > > >

> > > > > Ulcerative colitis is linked to overgrowth with

> pathogenic

> > > > microbes, the

> > > > > same as Crohn's disease, osteoporosis and

ankylosing

> > > spondylitis.

> > > > In

> > > > > ankylosing spondylitis the vertebra of the spine

fuse

> > together

> > > > causing

> > > > > stiffness and pain. Other joints may in time become

> > affected.

> > > > >

> > > > > Klebsiella, another type of pathogenic bacteria,

> produces a

> > > > molecule that is

> > > > > similar to a tissue type found in people with this

> disease.

> > > When

> > > > klebsiella

> > > > > numbers in the gut decrease, related antibodies in

the

> > blood

> > > > decrease and

> > > > > the condition improves.

> > > > >

> > > > > Rheumatoid arthritis is linked to other bacteria,

> called

> > > proteus.

> > > > Proteus is

> > > > > also a common cause of urinary tract infections.

Women

> > suffer

> > > > urinary tract

> > > > > infections as well as rheumatoid arthritis twice as

> often

> > as

> > > men,

> > > > while men

> > > > > usually have higher levels of klebsiella and three

> times

> > more

> > > > ankylosing

> > > > > spondylitis than women.

> > > > >

> > > > > In addition microbial overgrowth dam ages the

> intestinal

> > wall

> > > so

> > > > that only

> > > > > partly digested food particles can pass into the

> > bloodstream,

> > > > causing

> > > > > allergies. In this way all auto-immune diseases

can be

> > linked

> > > to

> > > > food

> > > > > allergies.

> > > > >

> > > > > While rheumatoid arthritis is a frequent feature

of the

> > > antibiotic

> > > > syndrome,

> > > > > and I regard it as relatively easy to cure, not

many

> > sufferers

> > > of

> > > > this

> > > > > disease seem to be interested in this natural

> approach. The

> > > other

> > > > day a

> > > > > young man with severe rheumatoid arthritis knocked

at

> my

> > door

> > > to

> > > > collect

> > > > > money for a medically sponsored walkathon. When I

told

> him

> > > that I

> > > > do not

> > > > > give money for drug treatment as it can be overcome

> with

> > > natural

> > > > therapies,

> > > > > he shouted: 'You are mad!' and left visibly upset.

> > > > >

> > > > > Other auto-immune diseases that have so far been

> linked to

> > > > dysbiosis are

> > > > > psoriasis, lupus erythematosus and pancreatitis.

When

> > remedies

> > > are

> > > > given

> > > > > that bind bacterial endotoxins, these conditions

> usually

> > > improve.

> > > > A further

> > > > > consequence of dysbiosis is susceptibility to food

> > poisoning as

> > > > with

> > > > > salmonella bacteria, while a healthy intestinal

flora

> > prevents

> > > > these from

> > > > > multiplying and causing trouble.

> > > > >

> > > > > Staphylococcus aureus or golden staph cause serious

> > infections

> > > in

> > > > hospital

> > > > > patients. It has been found that not only golden

staph

> but

> > also

> > > > other

> > > > > infections are greatly potentised when they occur

with

> a

> > > Candida

> > > > overgrowth.

> > > > > As Candida overgrowth is a natural outcome of the

> standard

> > > hospital

> > > > > treatment, it is easy to see why golden staph is so

> deadly

> > in

> > > > hospitals.

> > > > >

> > > > > A similar picture emerges with AIDS. People do not

die

> > from the

> > > > AIDS virus

> > > > > but from Candida-potentised bacterial infections. I

> also

> > see

> > > the

> > > > > antibiotic-induced dysbiosis in babies and infants

as

> the

> > main

> > > > cause of

> > > > > their frequent infections, glue ear and greatly

> > contributing to

> > > > cot death.

> > > > >

> > > > > While it used to be uncommon for children to have

more

> than

> > > one or

> > > > two

> > > > > infections a year, now more than six is the norm.

> > > > >

> > > > > In the 1940's Candida was found in only three per

cent

> of

> > > > autopsies, now the

> > > > > figure is nearer thirty per cent. There are, of

course,

> > other

> > > > factors that

> > > > > can cause dysbiosis - the contraceptive pill,

steroids

> and

> > > other

> > > > drugs,

> > > > > radiation treatment and chemotherapy - but the main

> > culprit is,

> > > > without

> > > > > doubt, antibiotics.

> > > > >

> > > > > Closely related to Candida are the mycoplasms or

> > pleomorphic

> > > > organisms.

> > > > > These have been shown to be a main factor in the

> causation

> > of

> > > > cancer.

> > > > > Therefore, antifungal therapy has also major

benefits

> in

> > cancer

> > > > treatment.

> > > > >

> > > > > Dr Orian Truss

> > > > >

> > > > > [infections] J -

guts

> > > > >

> > > > >

> > > > > Do you support your gut-symbiosis emphasis mostly

> from

> > > observing

> > > > the

> > > > > circumstances/course of human illness as

reported in

> > patient

> > > > > testimony online?

> > > > >

> > > > > Have you seen this one?

> > > > >

> > > > >

> > > > >

> > > > > Arthritis Rheum. 2000 Nov;43(11):2583-9. Related

> > Articles,

> > > Links

> > > > >

> > > > > Oral antibiotics as a novel therapy for

arthritis:

> > evidence

> > > for a

> > > > > beneficial effect of intestinal Escherichia coli.

> > > > >

> > > > > Nieuwenhuis EE, Visser MR, Kavelaars A, Cobelens

PM,

> > Fleer A,

> > > > Harmsen

> > > > > W, Verhoef J, Akkermans LM, Heijnen CJ.

> > > > >

> > > > > Wilhelmina Children's Hospital, Utrecht, The

> Netherlands.

> > > > >

> > > > > OBJECTIVE: The intestinal flora is thought to

play an

> > > important

> > > > role

> > > > > in regulation of immune responses. We

investigated

> the

> > > effects of

> > > > > changing the intestinal flora on the course of

> adjuvant-

> > > induced

> > > > > arthritis (AIA) and on experimental autoimmune

> > > encephalomyelitis

> > > > > (EAE) by the use of oral antibiotics. METHODS:

Oral

> > treatment

> > > > with

> > > > > either vancomycin or vancomycin, tobramycin, and

> > colistin was

> > > > started

> > > > > after AIA and EAE induction. Clinical symptoms

of AIA

> > and EAE

> > > > were

> > > > > monitored, and microbial analysis of ileal

samples

> was

> > > performed.

> > > > > RESULTS: Oral vancomycin treatment after disease

> > induction

> > > > > significantly decreased clinical symptoms of AIA.

> > > Simultaneously,

> > > > > increased concentrations of Escherichia coli were

> > detected

> > > in the

> > > > > distal ileum of vancomycin-treated rats. Ileal

> > > concentrations of

> > > > E

> > > > > coli were inversely related to disease scores in

rats

> > with

> > > AIA.

> > > > > Coadministration of colistin/tobramycin to

prevent

> the

> > > increase

> > > > in E

> > > > > coli abrogated the beneficial effect of

vancomycin on

> > AIA.

> > > > Vancomycin

> > > > > treatment also reduced the clinical symptoms of

EAE.

> > > CONCLUSION:

> > > > We

> > > > > propose oral vancomycin as a novel therapeutic

> strategy

> > in

> > > > autoimmune

> > > > > diseases.

> > > > >

> > > > > PMID: 11083284 [PubMed - indexed for MEDLINE]

> > > > >

> > > > >

> > > > >

> > > > >

> > > > >

> > > > >

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