Barb - LYMErix - big correction

[Guest guest]

Whoa, like hold the phone, maybe I totally missed the bus with this

stuff.

I dont think this paper (PMID: 10913394) is free, but it has

before/after/way-after blots from a number of people. All the WBs are

depicted in the paper, and the abstract which you can see in pubmed

describes them accurately. I dont think any of these subjects got sick

from LYMErix, but almost all did develop a bunch of crap on their WBs.

One FDA-approved blot was used and on that one the vaccination caused

a huuuge crappy smear to come up. The authors also made their own in-

house WB and on that WB no smear was elicited, rather some pretty nice

bands.

BUT heres the BIG thing, when they prepared an in-house WB using

organisms lacking the OspA plasmid, ALL the vaccine-induced reactivity

was ABSENT. Apparantly only *one* such OspA-plasmid-negative WB was

performed on a positive control patient serum, but it looks much the

same as the WB utilizing the wild type.

Are these guys (Philip J. Molloy, Victor P. Berardi, H. Persing,

and Leonard H. Sigal) like some sort of known rubes/scoundrels, or

does this not clear up the " multiple bands " thing? It sure looks like

OspA gets stuck to other proteins, or else dimerizes, degrades, etc,

producing proteins/complexes of all kinds of different molecular

weights.

If so, why does Fawcett write in 2004,

http://www.pubmedcentral.gov/articlerender.fcgi?artid=85737#B13

citing the Molloy study I discuss above, as tho said finding did not

exist? Hes talking about possible shared epitopes between OspA and

other proteins, ie other proteins being built of some of the same

parts as OspA. That is not consistent with the Molloy data.

It doesnt look like LYMErix really causes seroconversion against

multiple Bb proteins. However the vaccine-induced illnesses, and their

response to antibiotics in Donta's clinic, remain fascinating.