Guest guest Posted August 21, 2005 Report Share Posted August 21, 2005 From my reading on immune modulation, the Th1 repsonse is supressed in favor of the Th2 response in many viral and intracellular infections. In fact there are intracellular viral and bacterial pathogens that even will produce Il-10 binding ligands or promotors for Il-10 synthesis. What this does is increase Th2 dominance at the expense of the cell mediated respeonse. This may play a role in the anergic cell mediated immune response towards intracellular pathogens as the cell mediated response is suppressed in Th2 dominant states. You find high titers or EBV, candida and intracellular infections in Th1 suppression. An additional mechanism is through human immunization protocols that skews the immune response towards Th2 dominace. DPT and all of the other crap that is injected into children is creating Th2 dominance as evidenced by increased atopy, asthma, food allergies. Who's to say that the weakened Th1 response doesn't start with childhood immunizations and then weaken even further with pathogens that are immune system resistant as well as antobiotic resistant. After passing through how many billions of immune systems does it take before the pathogens develop defense strategies that allow them to exist in their host by subverting the immune responses. Contemplating this makes Beta lactamase seem like childs play. Not only are there antibiotic resistant pathogens, they are also immune system resistant. You can weaken the bugs all day long as best as you can with combinations of anitbiotics, but if you can't get your immune system to clear the infected cells and kill the bugs, they are not likely to cease to exist in their host. Finding the underlying immune system defect and correcting it is the job of the researchers. Who has had their immune systems tested lately to see what cells dominate, what functionality dominates, what cytokines are being produced. Something as simple as a PHA proliferation assay and cytokine assay or a mixed lymphocyte assay would shed some light on the status of one's underlying immune response. But how are you expected to get this when you can't even get a nasal culture to find out what bugs you do have. When doctors finally understand medicine, these problems will be solved. Tom Brown Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.