: cytokine supression by pathogens

[Guest guest]

:

Yes- and Lyme uses decorin binding proteins to hide from the

immune system upon initial infection.

And if it can also selectively supress the cytokines expression

we need to help it - then it's easier to imagine how high the pro-

inflammatory cytokines can be... and without the opposition of the

regulatory cytoines.. you have run away high level inflammation.

You may have missed the paper on Malaria that I cited to

recently. You may find this paper intersting as well.

Yes.. some pathogens direct the immune system for their own gain -

THAT'S what we were talking about a few days ago.

That's why there's a need to a modulator... and it would be nice to

know which one would be the correct one (based on what they actually

do... hense our discussion on Benicar and HCQ).

Barb

> > :

> >

> > Here are a few abstracts about HCQ as an immune modulator -

> > selectively supressing pro inflammatory cytokines.

> > And like all effective drugs- it can have side effects- I've

added

> > one abstract at the end re muscle weakness.

> >

> >

> > SELECTIVE cytokine regulation by HCQ

> > http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?

> > cmd=Retrieve & db=PubMed & list_uids=8336306 & dopt=Abstract

> >

> >

> > HCQ as a microglia modulator

> > http://www.immuno2004.org/onlineabstracts/2322.html

> >

> > HCQ side-effects (muscle weakness).

> > http://www3.interscience.wiley.com/cgi-

> bin/abstract/110433649/ABSTRACT

> >

> >

> >

> > wrote in part:

> > Barb Peck's done a masterful job of documenting the value of HCQ

in

> > alkalizing the cell compartment to maximize both antibiotic and

> > antifungal drug action against bugs, but it also has an immune mod

> > effect which I don't entirely understand. i think it might be an

> > interesting one to look at.