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IgG/IgM

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Per my LLMd, IgG shows positive when the Bb come out of cystic form,

which seems to go along with the info Barb has provided.

My only Igenix (done this spring) shows +ve for both IgG and IgM;

IgG IgM

18 ++ +/-

30+++ +

31 +/- -

34 +/- +/-

39 +/- +

41 ++ +++

45 +/- +/-

58 + ++

66 +/- +/-

93 +/- +

I had been on Minocin 100 mg 3 days a week (per AP for RA/Roadback)

for over 21/2 years.

Robyn

> Deb:

> You probably did have a good IgM response when you first got

> infected with Lyme - but it wasn't caught. But IgMs can't kill

Lyme-

> they're a smaller antibody than IgG, and they only live about 3

> months or less. If Lyme hides before the cells can gear up to make

> IgGs, then well- they don't get made.

> So then, when Lyme goes out into the blood to trvael from point

A

> to pont B - the body spikes another round of IgMs... but Lyme

> probably reaches it's sequestered destination before the body can

> make IgG.. so you never make them.

>

> The theory behind damaging or killing them with abx is to drive

> either the bacteria or their DNA out of hiding and into the blood.

> Keep it there long enough, and the body WILL make IgGs - and they

are

> long lived.

>

> In 2002 - I tested positive for Lyme by PCR,

> but my IgM was negative, only showed positive on (+) band 41 and I

> had ZERO activity on the IgG nothing at all.

>

> In 2003 - I didn't have PCR done.

> I was negative IgM on the western blot with only 2 positive bands

41

> and 66 and no other bands were even +/-.

> My IgG showed positive (+) on bands 34 and 41,

> Indeterminate bands (+/-) were 31, 45 & 58.

>

> In 2004- I didn't have PCR done.

> My IgM was considered positive with positive(+ or ++) bands 18,

39,

> 41, 66 & 93 and the indeterminate bands (+/-) on 23, 30, 31, 34, 45

&

> 58.

> the IgG was considered negative, but it was starting to turn on..

I

> was +/- on bands 18,23,31,34,39,41,45,58,and 66.

>

> I like Igenex, because they give you the indeterminate (+/-) bands.

> I look at this as raw data - and in my case it shows that my immune

> system is turning on against Lyme- albeit the IgG is not as robust

as

> I'd like to see it.

>

> So, at this point, I really don't even care whether the blots are

> considered " Positive or Negative " .. I look at the activity of the

> immune system, how I'm feeling, and hope that the IgGs continue to

be

> active (becuase they're the killers).

>

> I get tested again in a few months - and I think this year I'll

> include PCR with the blots.

>

> Barb

>

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