nitroimidazoles

[Guest guest]

My take (not empirical but looking at the Brorson papers which finds

Bb helices invulnerable to nitroimidazoles) is that I need to couple

my nitros with something that will definitely hit the brain in case

any borrelial helices crop up there, or for that matter any other

form that may not be too vulnerable to the nitros because of having

too much oxygen.

Stratton and/or Wheldon cleverly point out that protein synth

inhibitors can attenuate the DNA repair response, thus increasing

the chances fladg/tini will do mortal damage to the DNA. My

perspective on that is that if synth inhibitors were successfully

shutting down the bugs synth, we should probably all be cured after

a month of doxy. Still, it could well be that synth inhibitors do

slow down synth (and thus DNA repair) substantially enough for this

synergy with nitros to be realized.

I think there may be more on nitros re Cpn that I havent read about.

I havent even read the Stratton patent yet but I will.

> > Penny,

> >

> > >CFSExperimental was the only group that was broad minded

enough to

> > >entertain the notion (although people could get pretty riled

up

> > >there too, considering more people believed in viral

infections

> >

> > I have been on CFSExperimental since it was created (in fact

even

> before that, when it was owned by Clements, does anyone

> remember, in the 90s?) and I ALWAYS talked about bacterial

infections

> and abx. I don't think I was ever yelled off from other forums

for

> mentioning bacterial infections nor was I told I didn't have

CFS.

> >

> > I became ill in late 81 (mainly gut symptoms with low-grade

fever

> weight loss and fatigue) and a few months later developed a very

nice

> EM Lyme rash. Doctors in Sydney-Australia made me look such a

fool

> for insisting it was infectious that I nearly lost it. Not only

was I

> desperately ill but I had to fight single-handedly against the

whole

> entire world!

> >

> > The 80s were one long and absolutely incredible struggle on

all

> fronts having lost absolutely everything-health, job, husband,

> friends, family (I don't think I am forgetting anything:)). I

had the

> most incredible struggle with the %à§! & medical ç%!!!!ssss to

get abx

> and stay alive.

> >

> > BTW, Penny, Flagyl (metronidazole) was the abx that REALLY

made a

> difference back then, it made me feel cured. I remain convinced

that

> if I had been able to stay on it for a decent period at the

time, I

> would have had a good chance of a complete recovery.

> >

> > And all these years down the track, and after many other

adventures

> including many further tick-bites, Tinidazole is still the abx

that

> can get me vertical and functioning within hours of taking it.

When I

> am really, really bad, that's what I reach for (again a few days

ago).

> >

> > I don't think you should feel terrified of Flagyl, although it

can

> give me really bad headaches (just about everything that works

does

> after a few days anyway), it is an absolute must for me. It

saved my

> present husband's brain too on many occasions, and he has got to

keep

> his job as I certainly can't work for a living.

> >

> > Nelly

>

>

>

>

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