Mark, others - Th2, IL-10, profound immunosuppression by borrelia

[Guest guest]

Mark have you checked this free text out? The results are STRIKING

but I'm still not sure I didnt see them disconfirmed somewhere

else... this one has been on my mind a long time and I lost track of

the results I thought might contradict it...

It says lyme patient PBMC had a 70 PERCENT reduced IFNg and TNFa

response to LPS, compared to healthies.

Doing the same comparison using borrelia lysate (which lacks LPS but

has other innate immune system ligands) as the stimulant found the

same 70 percent attenuation for TNF response vs controls, but this

time not 70 but 92 DAMN PERCENT for IFNg!

Now thats what I call immunosuppression! I aint *even* lying! This

is right from the abstract of this paper:

http://www.pubmedcentral.gov/articlerender.fcgi?artid=97940

This followup says IL-10 is the primary mediator of this sorry pro-

inflammatory output:

http://www.pubmedcentral.gov/articlerender.fcgi?

tool=pubmed & pubmedid=12819085#r8

If this stuff is actually correct, its like, important.