Guest guest Posted February 3, 2004 Report Share Posted February 3, 2004 This was just posted to the CS Cats and Dogs list. Thought I would forward it on. Garnet -----Forwarded Message----- From: CSCats-Dogs To: CSCats-Dogs Subject: [CSCats-Dogs] File - What is DMSO Date: Tue, 03 Feb 2004 11:53:23 +0000 DMSO is a very valuable adjunct to the use of CS. This info comes from the book The Miracle of MSM-The Natural Solution for Pain, written by Stanely ,MD, Lawrence, MD, PHD., and Zucker, copyright 1999. Chapter 2 titled: Roots of MSM-The DMSO Connection this chapter written Dr. Stanley : Dr. Stanely appeared on a piece on 60 minutes, March 1980. At the time he was doing intravenous DMSO treatments for pain control. The piece centered on a woman who had suffered severe chronic whiplash and nerve damage in an auto accident in 1978. After 3 days of treatment, all observed on film, she no longer required any pain meds. This woman, as of the 1998 writing was/is STILL pain free. DMSO= dimethyl sulfoxide. Dr. had already been working with DMSO for more than 15 years when the piece was produced. DMSO a naturally occurring sulfur compound was first synthesized a hundred and thirty years ago by a russian chemist. In the process of transplantation research, Dr. found a scientific paper written by a British scientist named Lovelock about various chemical compounds that permitted freezing red blood cells ''alive''.One of those compounds was DMSO. A company named Crown-Zellerbach Corp., a large paper making company was producing DMSO. Herschler, a chemist had made the observation that in plants and trees DMSO tended to move through tissues and could carry other materials with it. They found, through research that it did the same in animals. DMSO had the potential to carry medications through the skin and into the body. The DMSO also demonstrated potent pain-reduction and anti-inflammatory properties for people. Applied over an acute sprain or burn, one could see the swelling resolve within an hour. DMSO also is a diuretic, has antibacterial effects and even rendered resistant bacteria vulnerable to the same antibiotics to which they had previously been resistant. In regards to transplantation, it is today used globally for the purpose of a preservative for transplantation- bound frozen bone marrow, platelets,embryos,ova and sperm cells. (ova and sperm cells, if it causes birth defects, why widely used to preserve these things?) Dr. first reported his development in 1963, of the use of DMSO for the relief of the pain of people with severe, unresolved arthritis, bursitis,tendinitis, and many other conditions. Articles began to appear in newspapers,including The New York Times describing DMSO as the ''most exciting thing in medicine.'' Now the pharmaceuticals and big government get involved...the PC were primarily interested in DMSO as a through the skin carrier of their own patented medicines. By 1965, more than 1500 studies had been conducted, involving about 100,00 patients.. Now this is where the confusion about birth defects, etc probably comes in...... During that year, the US FDA responsible for approving new drugs, temporarily stopped its consideration of medical uses for DMSO because of the flood of studies it had received and also out of fear of a Thalidomide-like nightmare occurring in the US. (for those that do not know or remember-Thalidomide had been discovered to cause serious deformities of the fetus when taken during pregnancy). The FDA was saying NO to EVERYTHING, including DMSO. The pharm companies subsequently lost interest in DMSO. 1970 approval was finally obtained for veterinary usage in the treatment of musculoskeletal disorders. Vets, still use it for this purpose on both large and small animals. 1978, the FDA finally approved DMSO as a prescriptive treatment for interstitial cystitis, a painful inflammatory condition of the bladder affecting a half-million women. IC remains the only disorder for which DMSO is approved by the FDA, despite numerous congressional hearings recommending wider application. It is still widely used by athletes for speedier healing of typical muscle, ligament and tendon injuries. A special law in the state of Oregon has allowed Dr. to use it for many other conditions. He continues to treat many other conditions and has helped many patients with a variety of severe disorders and musculoskeletal conditions. 1973, DMSO became prescriptive in Soviet Union-;prescribed there for an estimated 30 million patients annually for lupus, scleroderma, arthritis, diabetic ulcerations. Globally-is in about 125 countries, including Canada, Great Britain, Germany Switzerland. It has been the subject of 55,000 studies worldwide. " DMSO is safe, a substance of extraordinarily low toxicity, without a single documented death attributed to it. The most common side effect, if you want to call it that, is of the nuisance variety-the odor-it produces a distinctive fish-or oyster-like odor and taste in the mouth. " It is used widely internationally to reduce inflammation and carry critical medications through the skin in life-and-death trauma situations. (where the odor factor is irrelevant) This is where MSM comes in. MSM is the major metabolite of DMSO. When DMSO enters the body, 15% of it becomes MSM. A smaller percentage of DMSO is converted to DMS (dimethyl sulfide) the odor causing component of DMSO. MSM in itself does not penetrate the skin. DMSO does.... Now, the reason for mixing the CS with DMSO....simply put, it allows the CS to penetrate the skin. It is used as a transport of the CS when taken internally,inhaled etc. And Chuck (silver-list) posted this info several weeks back: http://www.dmso.org/articles/information/herschler.htm A wide range of primary pharmacological actions of dimethyl sulfoxide (DMSO)has been documented in laboratory studies: membrane transport, effects on connective tissue, anti-inflammation, nerve blockade (analgesia), bacteriostasis, diuresis, enhancements or reduction of the effectiveness of other drugs, cholinesterase inhibition, nonspecific enhancement of resistance to infection, vasodilation, muscle relaxation, antagonism to platelet aggregation, and influence on serum cholesterol in emperimental hypercholesterolemia. This substance induces differntiation and function of leukemic and other malignant cells. DMSO also has prophylactic radioprotective properties and cryoprotective actions. It protects against ischemic injury. (1986 Academic Press, Inc.) The pharmacologic actions of dimethyl sulfoxide (DMSO) have stimulated much research. The purpose of this report is to summarize current concepts in this area. When the theorectical basis of DMSO action is described, we can list literally dozens of primary pharmacologic actions. This relatively brief summary will touch on only a few: (A) membrane penetration ( membrane transport © effects on connective tissue (D) anti-inflamation (E) nerve blockade (analgesia) (F) bacteriostasis (G) diuresis (H) enhancement or reduction of effectiveness of other drugs (I) cholinsterase inhibition (J) nonspecific enhancement of resistance of infection (K) vasodilation (L) muscle relaxation (M) enhancement of cell differentiation and function (N) antagonism to platelet aggregation (O) influence on serum cholesterol in experimental hypercholesterolemia (P) radio-protective and cryoprotective actions (Q) protection against ischemic injury Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 3, 2004 Report Share Posted February 3, 2004 Thanks Garnet - god its sounds like an amazing substance. I am not at all surprised that it is hard to get, or has only been approved for Interstitial Cystitis - there simply is not anough profit in it for the Pharm co's! So, they keep it all under wraps! Def want to read Dr s book. Warmly, [DimethylSulfoxide-DMSO] What is DMSO This was just posted to the CS Cats and Dogs list. Thought I would forward it on. Garnet -- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 4, 2004 Report Share Posted February 4, 2004 I am wondering if you might know where to access the info about DMSO being used in rusia to treat lupis, it is mentioned VERY briefly in the article that you posted. My aunt has all three kinds of lupis, after first contracting she faught a coma for 3 months, finally came out, spent another 2 months in the hospital and now takes a BARRAGE of meds to keep her stable and alive all of which are detrimental to her....any ways, thanks for posting great info and starting group. I hope it grows as well as maintains a working useful amount of imput unlike some other groups. Donny > This was just posted to the CS Cats and Dogs list. Thought I would > forward it on. > > Garnet > > -----Forwarded Message----- > From: CSCats-Dogs > To: CSCats-Dogs > Subject: [CSCats-Dogs] File - What is DMSO > Date: Tue, 03 Feb 2004 11:53:23 +0000 > > > > DMSO is a very valuable adjunct to the use of CS. > > > This info comes from the book > The Miracle of MSM-The Natural Solution for Pain, written by > Stanely ,MD, > Lawrence, MD, PHD., and Zucker, > copyright 1999. > Chapter 2 titled: Roots of MSM-The DMSO Connection > this chapter written Dr. Stanley : > Dr. Stanely appeared on a piece on 60 minutes, March 1980. At > the time he > was > doing intravenous DMSO treatments for pain control. > The piece centered on a woman who had suffered severe > chronic whiplash > and > nerve damage in an auto accident in 1978. > After 3 days of treatment, all observed on film, she no longer > required any pain meds. > This woman, as of the 1998 writing was/is STILL pain free. > DMSO= dimethyl sulfoxide. Dr. had already been working > with DMSO > for > more > than 15 years when the piece was produced. > DMSO a naturally occurring sulfur compound was first > synthesized a hundred > and > thirty years ago by a russian chemist. > In the process of transplantation research, Dr. found a > scientific > paper > written by a British scientist named Lovelock about various > chemical > compounds > that permitted freezing red blood cells ''alive''.One of those > compounds was DMSO. > A company named Crown-Zellerbach Corp., a large paper > making company > was > producing DMSO. Herschler, a chemist had made the > observation that > in > plants and trees DMSO tended to move through tissues and > could carry other > materials with it. They found, through research that it did the > same in > animals. DMSO had the potential to carry medications through > the skin and > into > the body. The DMSO also demonstrated potent pain-reduction > and > anti-inflammatory properties for people. Applied over an acute > sprain or > burn, > one could see the swelling resolve within an hour. > DMSO also is a diuretic, has antibacterial effects and even > rendered > resistant > bacteria vulnerable to the same antibiotics to which they had > previously > been > resistant. > In regards to transplantation, it is today used globally for the > purpose of a preservative for transplantation- bound frozen bone > marrow, platelets,embryos,ova and sperm cells. > (ova and sperm cells, if it causes birth defects, why widely used > to > preserve > these things?) > Dr. first reported his development in 1963, of the use of > DMSO for the relief of the pain of people with severe, unresolved > arthritis, bursitis,tendinitis, and many other conditions. Articles > began to appear in newspapers,including The New York Times > describing DMSO as the ''most exciting thing in medicine.'' > Now the pharmaceuticals and big government get involved...the > PC were > primarily > interested in DMSO as a through the skin carrier of their own > patented > medicines. > By 1965, more than 1500 studies had been conducted, involving > about > 100,00 > patients.. > Now this is where the confusion about birth defects, etc probably > comes > in...... > During that year, the US FDA responsible for approving new > drugs, > temporarily > stopped its consideration of medical uses for DMSO because of > the flood of > studies it had received and also out of fear of a Thalidomide-like > nightmare occurring in the US. > (for those that do not know or remember-Thalidomide had been > discovered to > cause serious deformities of the fetus when taken during > pregnancy). The > FDA > was saying NO to EVERYTHING, including DMSO. The pharm > companies subsequently lost interest in DMSO. > 1970 approval was finally obtained for veterinary usage in the > treatment of musculoskeletal disorders. > Vets, still use it for this purpose on both large and small > animals. > 1978, the FDA finally approved DMSO as a prescriptive treatment > for > interstitial cystitis, a painful inflammatory condition of the bladder > affecting a half-million women. IC remains the only disorder for > which DMSO is approved by the FDA, despite numerous > congressional hearings > recommending wider application. It is still widely used by > athletes for speedier healing of typical muscle, ligament and > tendon injuries. > A special law in the state of Oregon has allowed Dr. to > use it for > many other conditions. He continues to treat many other > conditions and has helped many patients with a variety of severe > disorders and musculoskeletal conditions. > > 1973, DMSO became prescriptive in Soviet Union-;prescribed > there for an > estimated 30 million patients annually for lupus, scleroderma, > arthritis, > diabetic ulcerations. > Globally-is in about 125 countries, including Canada, Great > Britain, Germany Switzerland. It has been the subject of 55,000 > studies worldwide. > " DMSO is safe, a substance of extraordinarily low toxicity, without > a single documented death attributed to it. > The most common side effect, if you want to call it that, is of the > nuisance variety-the odor-it produces a distinctive fish-or > oyster-like odor and taste in the mouth. " > It is used widely internationally to reduce inflammation and carry > critical medications through the skin in life-and-death trauma > situations. (where the odor factor is irrelevant) > > This is where MSM comes in. > MSM is the major metabolite of DMSO. When DMSO enters the > body, 15% of > it > becomes MSM. A smaller percentage of DMSO is converted to > DMS (dimethyl > sulfide) the odor causing component of DMSO. > > MSM in itself does not penetrate the skin. > DMSO does.... > Now, the reason for mixing the CS with DMSO....simply put, it > allows the CS to penetrate the skin. It is used as a transport of > the CS when taken > internally,inhaled etc. > > > > > > > And Chuck (silver-list) posted this info several weeks back: > > http://www.dmso.org/articles/information/herschler.htm > > A wide range of primary pharmacological actions of dimethyl > sulfoxide > (DMSO)has been documented in laboratory studies: membrane > transport, effects on connective tissue, anti-inflammation, nerve > blockade (analgesia), bacteriostasis, diuresis, enhancements > or reduction of the effectiveness of other drugs, cholinesterase > inhibition, nonspecific enhancement of resistance to infection, > vasodilation, > muscle relaxation, antagonism to platelet aggregation, and > influence on > serum cholesterol in emperimental hypercholesterolemia. This > substance induces differntiation and function of leukemic and > other malignant cells. DMSO also has prophylactic > radioprotective properties and cryoprotective actions. It protects > against ischemic injury. (1986 Academic Press, Inc.) > > The pharmacologic actions of dimethyl sulfoxide (DMSO) have > stimulated > much > research. The purpose of this report is to summarize current > concepts in > this > area. > > When the theorectical basis of DMSO action is described, we > can list > literally > dozens of primary pharmacologic actions. This relatively brief > summary will touch on only a few: > > (A) membrane penetration > ( membrane transport > © effects on connective tissue > (D) anti-inflamation > (E) nerve blockade (analgesia) > (F) bacteriostasis > (G) diuresis > (H) enhancement or reduction of effectiveness of other drugs > (I) cholinsterase inhibition > (J) nonspecific enhancement of resistance of infection > (K) vasodilation > (L) muscle relaxation > (M) enhancement of cell differentiation and function > (N) antagonism to platelet aggregation > (O) influence on serum cholesterol in experimental > hypercholesterolemia > (P) radio-protective and cryoprotective actions > (Q) protection against ischemic injury > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 4, 2004 Report Share Posted February 4, 2004 www.dmso.org has some articles. Pub Med also, which I think they link to, is a medical data base of journal articles, you can choose options on an advanced search, but start at the dmso site. There is a book " MSM The Definitive Guide " that is suppose to have some info in it. I have ordered it and other and will post to the list when I can review them, should arrive along with a new Goodman and Gilman's Pharmacological Basis of Therapeutics (Pharmacology text book), and one other older DMSO book this next week. Dr Stanley s treats patients in Oregon. He has a link to the DMSO.org site, you can also buy the above book from him or Amazon. I have a friend that is using it for Lupus, with her doctors blessings. She is now off all cortisone injections. I am hoping she will join this list and share her experience. She is on a horse list I am on. Horse people use a lot of DMSO. Garnet > I am wondering if you might know where to access the info about DMSO > being used in rusia to treat lupis, it is mentioned VERY briefly in > the article that you posted. My aunt has all three kinds of lupis, > after first contracting she faught a coma for 3 months, finally came > out, spent another 2 months in the hospital and now takes a BARRAGE > of meds to keep her stable and alive all of which are detrimental to > her....any ways, thanks for posting great info and starting group. I > hope it grows as well as maintains a working useful amount of imput > unlike some other groups. > Donny Quote Link to comment Share on other sites More sharing options...
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